Aliases for ASIC5 Gene
External Ids for ASIC5 Gene
Previous HGNC Symbols for ASIC5 Gene
Previous GeneCards Identifiers for ASIC5 Gene
This gene belongs to the amiloride-sensitive Na+ channel and degenerin (NaC/DEG) family, members of which have been identified in many animal species ranging from the nematode to human. The amiloride-sensitive Na(+) channel encoded by this gene is primarily expressed in the small intestine, however, its exact function is not known. [provided by RefSeq, Jul 2008]
GeneCards Summary for ASIC5 Gene
ASIC5 (Acid Sensing Ion Channel Subunit Family Member 5) is a Protein Coding gene. Diseases associated with ASIC5 include Pregnancy Loss, Recurrent 3 and Pseudohypoaldosteronism. Among its related pathways are Ion channel transport and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include sodium channel activity and proton channel activity. An important paralog of this gene is SCNN1G.
UniProtKB/Swiss-Prot Summary for ASIC5 Gene
Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride.