Aliases for ASIC4 Gene
Aliases for ASIC4 Gene
External Ids for ASIC4 Gene
- HGNC: 21263
- Entrez Gene: 55515
- Ensembl: ENSG00000072182
- OMIM: 606715
- UniProtKB: Q96FT7
Previous HGNC Symbols for ASIC4 Gene
- ACCN4
Previous GeneCards Identifiers for ASIC4 Gene
- GC02P218401
- GC02P219100
- GC02P220378
Summaries for ASIC4 Gene
-
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012]
GeneCards Summary for ASIC4 Gene
ASIC4 (Acid Sensing Ion Channel Subunit Family Member 4) is a Protein Coding gene. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Ion channel transport. Gene Ontology (GO) annotations related to this gene include ion channel activity and sodium ion transmembrane transporter activity. An important paralog of this gene is ASIC1.
UniProtKB/Swiss-Prot for ASIC4 Gene
-
Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity.
-
Acid-sensing ion channels (ASIC) are members of the ENaC/Deg (epithelial amiloride-sensitive Na+ channel and degenerin) family of ion channels and are widely expressed in neurons of the central and peripheral nervous system.
No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ASIC4 Gene
Genomics for ASIC4 Gene
GeneHancer (GH) Regulatory Elements for ASIC4 Gene
Promoters and enhancers for ASIC4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around ASIC4 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for ASIC4 Gene
Genomic Locations for ASIC4 Gene
- chr2:219,514,170-219,538,772
- (GRCh38/hg38)
- Size:
- 24,603 bases
- Orientation:
- Plus strand
- chr2:220,378,892-220,403,494
- (GRCh37/hg19)
- Size:
- 24,603 bases
- Orientation:
- Plus strand
Genomic View for ASIC4 Gene
Genes around ASIC4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q35 by Entrez Gene
- 2q35 by HGNC
- 2q35 by Ensembl
ASIC4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ASIC4 Gene
Proteins for ASIC4 Gene
-
Protein details for ASIC4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96FT7-ASIC4_HUMAN
- Recommended name:
- Acid-sensing ion channel 4
- Protein Accession:
- Q96FT7
- Q53SB7
- Q6GMS1
- Q6PIN9
- Q9NQA4
Protein attributes for ASIC4 Gene
- Size:
- 647 amino acids
- Molecular mass:
- 70105 Da
- Quaternary structure:
-
- Homotrimer or heterotrimer with other ASIC proteins.
- SequenceCaution:
-
- Sequence=CAB93980.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAC51338.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for ASIC4 Gene
Post-translational modifications for ASIC4 Gene
Other Protein References for ASIC4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for ASIC4
- Novus Biologicals Antibodies for ASIC4
-
Abcam antibodies for ASIC4
- Invitrogen Antibodies for ASIC4
- GeneTex ASIC4 Antibody for ASIC4
-
Boster Bio Antibodies for ASIC4
-
Santa Cruz Biotechnology (SCBT) Antibodies for ASIC4
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for ASIC4
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- Novus Biologicals lysates for ASIC4
- antibodies-online: Search results for 6 available ACCN4 Proteins ranked by validation data
- Compare Top ACCN4 Proteins
-
Quality Products:
- Search GeneTex for Proteins for ASIC4
Assay Products
No data available for DME Specific Peptides for ASIC4 Gene
Domains & Families for ASIC4 Gene
Gene Families for ASIC4 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Protein Domains for ASIC4 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ASIC4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q96FT7UniProtKB/Swiss-Prot:
ASIC4_HUMAN :- Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC4 subfamily.
- Family:
-
- Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC4 subfamily.
Function for ASIC4 Gene
Molecular function for ASIC4 Gene
- UniProtKB/Swiss-Prot Function:
- Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity.
Phenotypes From GWAS Catalog for ASIC4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005216 | ion channel activity | TAS | 10852210 |
| GO:0005272 | sodium channel activity | IEA | -- |
| GO:0015081 | sodium ion transmembrane transporter activity | TAS | 10852210 |
Phenotypes for ASIC4 Gene
- MGI mutant phenotypes for ASIC4:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for ASIC4:
Animal Models for ASIC4 Gene
Animal Model Products
-
Taconic Biosciences Mouse Models for ASIC4
- Cyagen custom Knockout/knockin (KOKI) mouse models for ASIC4
-
CRISPR Products
-
OriGene CRISPR knockouts for ASIC4
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- genomics-online: gRNA clones - Search results for available ACCN4 gene related products
- Applied Biological Materials CRISPR for ASIC4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ASIC4
- GenScript: Design CRISPR guide RNA sequences for ASIC4
miRNA for ASIC4 Gene
- miRTarBase miRNAs that target ASIC4
-
- hsa-mir-335-5p (MIRT018746)
- hsa-mir-6823-3p (MIRT713967)
- hsa-mir-5006-3p (MIRT713968)
- hsa-mir-4755-5p (MIRT713969)
- hsa-mir-6868-3p (MIRT713970)
- hsa-mir-6881-3p (MIRT713971)
- hsa-mir-6780a-3p (MIRT713972)
- hsa-mir-7111-3p (MIRT713973)
- hsa-mir-211-5p (MIRT713974)
- hsa-mir-204-5p (MIRT713975)
- hsa-mir-623 (MIRT713976)
- hsa-mir-642a-5p (MIRT713977)
- hsa-mir-6845-3p (MIRT713978)
- hsa-mir-4469 (MIRT713979)
- hsa-mir-3667-3p (MIRT713980)
- hsa-mir-6734-3p (MIRT713981)
- hsa-mir-6769b-3p (MIRT713982)
- hsa-mir-4723-3p (MIRT713983)
- hsa-mir-3183 (MIRT713984)
- hsa-mir-5088-3p (MIRT713985)
- hsa-mir-2276-5p (MIRT713986)
- hsa-mir-6892-3p (MIRT713987)
miRNA Products
Inhibitory RNA Products
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- genomics-online: shRNA clones - Search results for available ACCN4 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ASIC4
- VectorBuilder custom plasmid, inducible vectors for ASIC4
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ASIC4
- genomics-online: cdna clones - Search results for available ACCN4 gene related products
- orf clones - Search results for available ACCN4 gene related products
- Applied Biological Materials Clones for ASIC4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for ASIC4
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ASIC4 Gene
Localization for ASIC4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ASIC4 Gene
- Membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| golgi apparatus | 2 |
| extracellular | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005887 | integral component of plasma membrane | TAS | 10852210 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for ASIC4 Gene
Pathways & Interactions for ASIC4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Ion channel transport | ||
| 2 | Development Endothelin-1/EDNRA signaling | ||
| 3 | Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||
Pathways by source for ASIC4 Gene
3 Reactome pathways for ASIC4 Gene
1 KEGG pathway for ASIC4 Gene
Interacting Proteins for ASIC4 Gene
GPS-Prot Interaction Network for ASIC4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001662 | behavioral fear response | IEA | -- |
| GO:0006811 | ion transport | IEA | -- |
| GO:0006814 | sodium ion transport | IEA | -- |
| GO:0034220 | ion transmembrane transport | IEA | -- |
| GO:0035725 | sodium ion transmembrane transport | IEA | -- |
No data available for SIGNOR curated interactions for ASIC4 Gene
Transcripts for ASIC4 Gene
mRNA/cDNA for ASIC4 Gene
- (3) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (25) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000461395 3340 bps (uc002vly.3)
- ENST00000347842 2684 bps (uc002vma.4)
- ENST00000358078 2741 bps (uc061syq.1)
- ENST00000474489 2403 bps (uc002vmb.4)
- ENST00000473709 613 bps (uc061syr.1)
Unigene Clusters for ASIC4 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ASIC4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ASIC4
- genomics-online: gRNA clones - Search results for available ACCN4 gene related products
- Applied Biological Materials CRISPR for ASIC4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ASIC4
- GenScript: Design CRISPR guide RNA sequences for ASIC4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ASIC4
- Browse OriGene Inhibitory RNA Products For ASIC4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ASIC4
- genomics-online: shRNA clones - Search results for available ACCN4 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ASIC4
- VectorBuilder custom plasmid, inducible vectors for ASIC4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ASIC4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ASIC4
- genomics-online: cdna clones - Search results for available ACCN4 gene related products
- orf clones - Search results for available ACCN4 gene related products
- Applied Biological Materials Clones for ASIC4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||
| SP4: | - |
Expression for ASIC4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
-
Ovary (Reproductive System)
- Granulosa Cells Primary Follicle
mRNA differential expression in normal tissues according to GTEx for ASIC4 Gene
This gene is overexpressed in Pituitary (x20.2).
This gene is overexpressed in Adipocyte (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ASIC4 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ASIC4 Gene:
ASIC4SOURCE GeneReport for Unigene cluster for ASIC4 Gene:
Hs.87469mRNA Expression by UniProt/SwissProt for ASIC4 Gene:
Q96FT7-ASIC4_HUMAN
Tissue specificity:
Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti.
Evidence on tissue expression from TISSUES for ASIC4 Gene
- Nervous system(4.6)
Primer Products
-
OriGene qPCR primer pairs for ASIC4
- genomics-online: primer clones - Search results for available ACCN4 gene related products
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for ASIC4 Gene
Orthologs for ASIC4 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ACCN4 33 |
|
||
| ASIC4 34 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | ASIC4 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | ASIC4 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Asic4 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Asic4 16 34 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ASIC4 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ASIC4 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ASIC4 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | ASIC4 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | asic4 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | asic4a 34 33 |
|
OneToMany | |
| asic4b 34 |
|
OneToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | unc-105 35 |
|
|
|
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany |
- Species where no ortholog for ASIC4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for ASIC4 Gene
- ENSEMBL:
- Gene Tree for ASIC4 (if available)
- TreeFam:
- Gene Tree for ASIC4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ASIC4: view image
Paralogs for ASIC4 Gene
Variants for ASIC4 Gene
| SNP ID | Clin | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000076930 | -- | 219,519,223(+) | G/A | intron_variant | |
| rs1000338083 | -- | 219,531,348(+) | A/T | intron_variant | |
| rs1000365468 | -- | 219,524,771(+) | C/T | intron_variant | |
| rs1000366696 | -- | 219,521,066(+) | C/G | intron_variant | |
| rs1000439878 | -- | 219,515,879(+) | C/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant |
Residual Variation Intolerance Score:
54.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.27;
76.38% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ASIC4 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ASIC4 Gene
Disorders for ASIC4 Gene
Additional Disease Information for ASIC4
No disorders were found for ASIC4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ASIC4 Gene
Publications for ASIC4 Gene
- A new member of acid-sensing ion channels from pituitary gland. (PMID: 10852210) Gründer S … Ruppersberg JP (Neuroreport 2000) 2 3 4 58
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Acid-sensing ion channel (ASIC) 4 gene: physical mapping, genomic organisation, and evaluation as a candidate for paroxysmal dystonia. (PMID: 11571555) Gründer S … Fink JK (European journal of human genetics : EJHG 2001) 3 4 58
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
Products for ASIC4 Gene
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- VectorBuilder custom plasmid, inducible vectors for ASIC4
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 54 available ACCN4 Antibodies ranked by validation data
- Compare Top ACCN4 Antibodies
- antibodies-online: Search results for available ACCN4 related products ranked by validation data
- antibodies-online: Search results for 6 available ACCN4 Proteins ranked by validation data
- Compare Top ACCN4 Proteins
- Quality Products:
- GeneTex ASIC4 Antibody for ASIC4
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- Horizon Cell Lines for ASIC4
- genomics-online: cdna clones - Search results for available ACCN4 gene related products
- orf clones - Search results for available ACCN4 gene related products
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- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ASIC4
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- Boster Bio Antibodies for ASIC4
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Sources for ASIC4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
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- (40) DGV
- (41) dbSNP
- (42) GenAtlas
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- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
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- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
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- (112) RVIS
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- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt