Aliases for ASCC2 Gene
External Ids for ASCC2 Gene
Previous GeneCards Identifiers for ASCC2 Gene
GeneCards Summary for ASCC2 Gene
ASCC2 (Activating Signal Cointegrator 1 Complex Subunit 2) is a Protein Coding gene. Diseases associated with ASCC2 include Trichothiodystrophy 1, Photosensitive. Among its related pathways are DNA Damage Reversal and DNA Double-Strand Break Repair.
UniProtKB/Swiss-Prot for ASCC2 Gene
Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains (PubMed:29144457). Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347).