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This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene ... See more...
Aliases for ASB2 Gene
Aliases for ASB2 Gene
External Ids for ASB2 Gene
- HGNC: 16012
- NCBI Entrez Gene: 51676
- Ensembl: ENSG00000100628
- OMIM®: 605759
- UniProtKB/Swiss-Prot: Q96Q27
Previous GeneCards Identifiers for ASB2 Gene
- GC14M091907
- GC14M088217
- GC14M092390
- GC14M093470
- GC14M094400
- GC14M074580
Summaries for ASB2 Gene
-
This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
GeneCards Summary for ASB2 Gene
ASB2 (Ankyrin Repeat And SOCS Box Containing 2) is a Protein Coding gene. Diseases associated with ASB2 include Myeloid Leukemia and Acute Promyelocytic Leukemia. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include ubiquitin-protein transferase activity. An important paralog of this gene is UACA.
UniProtKB/Swiss-Prot Summary for ASB2 Gene
-
Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
-
[Isoform 1]: Enhances adhesion of hematopoietic cells to fibronectin through targeting of filamins FLNA and FLNB for proteasomal degradation, it is transiantly expressed during hematopoietic cell differentiation.
-
[Isoform 2]: Involved in myogenic differentiation and targets filamin FLNB for proteasomal degradation but not filamin FLNA.
Additional gene information for ASB2 Gene
- HGNC (16012)
- NCBI Entrez Gene (51676)
- Ensembl (ENSG00000100628)
- OMIM® (605759)
- UniProtKB/Swiss-Prot (Q96Q27)
- Open Targets Platform(ENSG00000100628)
- Search for ASB2 at DataMed
- Search for ASB2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ASB2 Gene
Genomics for ASB2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ASB2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ASB2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ASB2
- Top Transcription factor binding sites by QIAGEN in the ASB2 gene promoter:
-
- E2F
- E2F-1
- E2F-2
- E2F-3a
- E2F-4
- E2F-5
- GATA-2
- GATA-3
- YY1
Genomic Locations for ASB2 Gene
Latest Assembly
- chr14:93,934,160-93,976,739
- (GRCh38/hg38)
- Size:
- 42,580 bases
- Orientation:
- Minus strand
Previous Assembly
- chr14:94,400,512-94,442,916
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 42,405 bases
- Orientation:
- Minus strand
- chr14:94,400,499-94,443,137
- (GRCh37/hg19 by Ensembl)
- Size:
- 42,639 bases
- Orientation:
- Minus strand
Genomic View for ASB2 Gene
Genes around ASB2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q32.12 by HGNC
- 14q32.12 by Entrez Gene
- 14q32.12 by Ensembl
ASB2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ASB2 Gene
Proteins for ASB2 Gene
-
Protein details for ASB2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96Q27-ASB2_HUMAN
- Recommended name:
- Ankyrin repeat and SOCS box protein 2
- Protein Accession:
- Q96Q27
- B2RDP9
- B4E166
- Q9NSU5
- Q9Y567
Protein attributes for ASB2 Gene
- Size:
- 587 amino acids
- Molecular mass:
- 65084 Da
- Quaternary structure:
-
- Component of a probable ECS E3 ubiquitin-protein ligase complex which contains CUL5, either RBX1 or RNF7/RBX2, Elongin BC complex (ELOB and ELOC) and ASB2.
Protein Expression for ASB2 Gene
Post-translational modifications for ASB2 Gene
Other Protein References for ASB2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- Novus Biologicals Antibodies for ASB2
-
Abcam antibodies for ASB2
- Invitrogen Antibodies for ASB2 (AFLGC-ASB2)
-
Biorbyt antibodies for ASB2
-
Custom Antibody ServicesProSci Antibodies for ASB2
- Sino Biological Antibodies for ASB2
Protein products for research
-
OriGene Purified Proteins for ASB2
- Search Origene for MassSpec and Protein Over-expression Lysates for ASB2
- Origene Custom Protein Services for ASB2
- Novus Biologicals proteins for ASB2
- antibodies-online: Show 4 available ASB2 Proteins ranked by validation data
- Compare Top ASB2 Proteins
-
Quality Products:
-
Abcam proteins for ASB2
Assay products for research
- antibodies-online: Search results for available ASB2 related products ranked by validation data
No data available for DME Specific Peptides for ASB2 Gene
Domains & Families for ASB2 Gene
Gene Families for ASB2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for ASB2 Gene
- InterPro:
- Blocks:
-
- Ankyrin repeat signature
- SOCS protein, C-terminal
- ProtoNet:
Suggested Antigen Peptide Sequences for ASB2 Gene
- GenScript: Design optimal peptide antigens:
-
- Ankyrin repeat and SOCS box protein 2 (ASB2_HUMAN)
- cDNA FLJ32516 fis, clone SMINT1000103, highly similar to Ankyrin repeat and SOCS box protein 2 (B3KPZ6_HUMAN)
- cDNA FLJ56197, highly similar to Ankyrin repeat and SOCS box protein 2 (ASB-2) (B4E166_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q96Q27UniProtKB/Swiss-Prot:
ASB2_HUMAN :- The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes.
- Belongs to the ankyrin SOCS box (ASB) family.
- Domain:
-
- The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes.
- Both the N-terminus and ANK repeats 1 to 10 are necessary for interaction with filamins.
- Family:
-
- Belongs to the ankyrin SOCS box (ASB) family.
Function for ASB2 Gene
Molecular function for ASB2 Gene
- UniProtKB/Swiss-Prot Function:
- Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
- UniProtKB/Swiss-Prot Function:
- [Isoform 1]: Enhances adhesion of hematopoietic cells to fibronectin through targeting of filamins FLNA and FLNB for proteasomal degradation, it is transiantly expressed during hematopoietic cell differentiation.
- UniProtKB/Swiss-Prot Function:
- [Isoform 2]: Involved in myogenic differentiation and targets filamin FLNB for proteasomal degradation but not filamin FLNA.
- UniProtKB/Swiss-Prot Induction:
- By all-trans retinoic acid (ATRA).
Phenotypes From GWAS Catalog for ASB2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IEA,IPI | 16325183 |
| GO:0061630 | contributes_to ubiquitin protein ligase activity | IDA | 16325183 |
Phenotypes for ASB2 Gene
- MGI mutant phenotypes for ASB2:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for ASB2:
-
- no effect
- Decreased viability
- Decreased Sindbis virus (SIN) capsid and autophagosome LC3 protein colocalization
- Decreased viability after sindbis virus (SIN) dsTE12Q infection
- Decreased mitophagy mCherry-Parkin protein expression after carbonyl cyanide m-chlorphenylhydrazone (CCCP) stimulation
- Effect on mitosis, decreased viability (cell death)
Animal Models for ASB2 Gene
- MGI Knock Outs for ASB2:
-
- Asb2 Asb2<tm2b(KOMP)Wtsi>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for ASB2 - Starting at $85 >
- * ASB2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for ASB2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ASB2
-
Santa Cruz Biotechnology (SCBT) CRISPR for ASB2
miRNA for ASB2 Gene
- miRTarBase miRNAs that target ASB2
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ASB2
- Browse OriGene Inhibitory RNA Products For ASB2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ASB2
Clone products for research
- Applied Biological Materials (abm): Clones for ASB2 - Starting at $45 >
- * ASB2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for ASB2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ASB2
Cell Lines for research
-
Horizon Cell Lines for ASB2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ASB2 Gene
Localization for ASB2 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| mitochondrion | 3 |
| nucleus | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| endoplasmic reticulum | 1 |
| lysosome | 1 |
- Cytosol (2)
- Nucleoli fibrillar center (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000151 | ubiquitin ligase complex | IDA | 16325183 |
| GO:0005829 | cytosol | TAS | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for ASB2 Gene
Pathways & Interactions for ASB2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Class I MHC mediated antigen processing and presentation | ||
| 2 | Innate Immune System |
.61
|
|
Pathways by source for ASB2 Gene
UniProtKB/Swiss-Prot Q96Q27-ASB2_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for ASB2 Gene
Selected Interacting proteins:
Q96Q27-ASB2_HUMAN
ENSP00000451575
for ASB2 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for ASB2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006511 | ubiquitin-dependent protein catabolic process | IBA | 21873635 |
| GO:0007165 | signal transduction | TAS | 9419338 |
| GO:0016567 | protein ubiquitination | IBA,IEA | -- |
| GO:0035556 | intracellular signal transduction | IEA | -- |
| GO:0035914 | skeletal muscle cell differentiation | IEA | -- |
No data available for SIGNOR curated interactions for ASB2 Gene
Transcripts for ASB2 Gene
mRNA/cDNA for ASB2 Gene
- 2 REFSEQ mRNAs :
- 11 NCBI additional mRNA sequence :
- 10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000315988 2743 nts (view in UCSC)
- ENST00000553883 2168 nts (view in UCSC)
- ENST00000555019 2608 nts (view in UCSC)
- ENST00000555287 661 nts (view in UCSC)
- ENST00000555374 396 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for ASB2 - Starting at $85 >
- * ASB2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for ASB2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ASB2
-
Santa Cruz Biotechnology (SCBT) CRISPR for ASB2
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ASB2
- Browse OriGene Inhibitory RNA Products For ASB2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ASB2
Clone products for research
- Applied Biological Materials (abm): Clones for ASB2 - Starting at $45 >
- * ASB2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for ASB2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ASB2
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | ^ | 9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | |||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||||||
| SP6: | - | - |
Relevant External Links for ASB2 Gene
- GeneLoc Exon Structure for
- ASB2
Expression for ASB2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Heart (Cardiovascular System)
- Atrioventricular Canal Cells Atrioventricular Canal
- Outflow Tract
- Cardiomyocyte-like progenitor cells(Uosaki H et. al. 2011)
- Gut Tube (Gastrointestinal Tract)
-
Skeletal Muscle (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for ASB2 Gene
This gene is overexpressed in Muscle - Skeletal (x21.0) and Heart - Left Ventricle (x4.8).
This gene is overexpressed in Ovary (64.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ASB2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ASB2
SOURCE GeneReport for Unigene cluster for ASB2 Gene:
Hs.510327Evidence on tissue expression from TISSUES for ASB2 Gene
- Kidney(4.3)
- Blood(4.3)
- Stomach(4.1)
- Muscle(3.6)
- Heart(2.8)
- Intestine(2.5)
Primer products for research
-
OriGene qPCR primer pairs for ASB2
-
OriGene qPCR primer pairs and template standards for ASB2
Gene Expression Assays for research
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ASB2 Gene
Orthologs for ASB2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ASB2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | ASB2 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | ASB2 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Asb2 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Asb2 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | ASB2 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | ASB2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | ASB2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | asb2 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | asb2a.1 30 31 31 |
|
OneToMany | |
| asb2b 31 |
|
OneToMany | |||
| Worm (Caenorhabditis elegans) |
Secernentea | M60.7 31 |
|
OneToMany |
- Species where no ortholog for ASB2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for ASB2 Gene
- ENSEMBL:
- Gene Tree for ASB2 (if available)
- TreeFam:
- Gene Tree for ASB2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ASB2: view image
Paralogs for ASB2 Gene
(16) SIMAP similar genes for ASB2 Gene using alignment to 5 proteins:
- ASB2_HUMAN
- G3V2Z2_HUMAN
- G3V3P8_HUMAN
- G3V484_HUMAN
- G3V4B2_HUMAN
Variants for ASB2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ASB2 Gene
| SNP ID | Clinical significance and condition | Chr 14 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs2295213 | - |
p.Pro160Ser |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
93.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.66;
65.77% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ASB2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ASB2
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ASB2 Gene
Disorders for ASB2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| myeloid leukemia |
|
|
| acute promyelocytic leukemia |
|
|
Search ASB2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ASB2
- Genetic Association Database
- (GAD)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for ASB2 Gene
Publications for ASB2 Gene
- ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex. (PMID: 15590664) Heuzé ML … Lutz PG (The Journal of biological chemistry 2005) 3 4 23
- ASB-2 inhibits growth and promotes commitment in myeloid leukemia cells. (PMID: 11682484) Guibal FC … Cayre YE (The Journal of biological chemistry 2002) 3 4 23
- ATRA-regulated Asb-2 gene induced in differentiation of HL-60 leukemia cells. (PMID: 11566180) Kohroki J … Tanaka K (FEBS letters 2001) 3 4 23
- Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4. (PMID: 11111040) Kile BT … Alexander WS (Gene 2000) 3 4 23
- ASB2α, an E3 ubiquitin ligase specificity subunit, regulates cell spreading and triggers proteasomal degradation of filamins by targeting the filamin calponin homology 1 domain. (PMID: 24052262) Razinia Z … Calderwood DA (The Journal of biological chemistry 2013) 3 4
ExternalLinks
Products for ASB2 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ASB2
- Search Origene for MassSpec and Protein Over-expression Lysates for ASB2
- Origene Custom Protein Services for ASB2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ASB2
- Browse OriGene Inhibitory RNA Products For ASB2
- OriGene qPCR primer pairs for ASB2
- OriGene qPCR primer pairs and template standards for ASB2
- OriGene CRISPR knockouts for ASB2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ASB2
- Sino Biological Human cDNA Clone for ASB2
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for ASB2
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for ASB2
- Novus Biologicals proteins for ASB2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for ASB2
- Abcam proteins for ASB2
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for ASB2 (AFLGC-ASB2)
- VectorBuilder Custom and pre-made DNA vectors for ASB2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for ASB2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for ASB2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for ASB2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for ASB2
- antibodies-online: Show 11 available ASB2 Antibodies ranked by validation data
- Compare Top ASB2 Antibodies
- antibodies-online: Search results for available ASB2 related products ranked by validation data
- antibodies-online: Show 4 available ASB2 Proteins ranked by validation data
- Compare Top ASB2 Proteins
- Quality Products:
- Custom Antibody ServicesProSci Antibodies for ASB2
- Search for ASB2 Proteins at ProSci
- Horizon Cell Lines for ASB2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ASB2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ASB2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for ASB2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ASB2
- Biorbyt antibodies for ASB2
Sources for ASB2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB