Aliases for ASAP3 Gene
External Ids for ASAP3 Gene
Previous HGNC Symbols for ASAP3 Gene
Previous GeneCards Identifiers for ASAP3 Gene
This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
GeneCards Summary for ASAP3 Gene
ASAP3 (ArfGAP With SH3 Domain, Ankyrin Repeat And PH Domain 3) is a Protein Coding gene. Among its related pathways are Fc gamma R-mediated phagocytosis and Endocytosis. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is ASAP2.
UniProtKB/Swiss-Prot Summary for ASAP3 Gene
Promotes cell proliferation.