Free for academic non-profit institutions. Other users need a Commercial license
This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have... See more...
Aliases for ART3 Gene
Aliases for ART3 Gene
External Ids for ART3 Gene
- HGNC: 725
- Entrez Gene: 419
- Ensembl: ENSG00000156219
- OMIM: 603086
- UniProtKB: Q13508
Previous GeneCards Identifiers for ART3 Gene
- GC04P076891
- GC04P077186
- GC04P077325
- GC04P077454
- GC04P077353
- GC04P076932
- GC04P072684
Summaries for ART3 Gene
-
This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
GeneCards Summary for ART3 Gene
ART3 (ADP-Ribosyltransferase 3) is a Protein Coding gene. Diseases associated with ART3 include Esophageal Candidiasis and Sciatic Neuropathy. Among its related pathways are Metabolism of proteins and NAD metabolism. Gene Ontology (GO) annotations related to this gene include NAD+ ADP-ribosyltransferase activity and NAD(P)+-protein-arginine ADP-ribosyltransferase activity. An important paralog of this gene is ART5.
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ART3 Gene
Genomics for ART3 Gene
GeneHancer (GH) Regulatory Elements for ART3 Gene
Promoters and enhancers for ART3 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH04J076011 | Promoter/Enhancer | 1.2 | Ensembl ENCODE CraniofacialAtlas | 559.9 | +1.1 | 1104 | 2.5 | NRF1 RELA BCL11A TCF12 CBFB POLR2A REST ARNT MEF2B JUND | ART3 NAAA NUP54 CXCL10 | |
| GH04J076074 | Promoter | 0.3 | EPDnew | 511.4 | +63.5 | 63514 | 0.1 | ART3 CXCL9 SDAD1 LOC101928809 CXCL10 PPEF2 KR153194-147 lnc-SCARB2-4 | ||
| GH04J075980 | Promoter | 0.3 | EPDnew | 500.3 | -30.4 | -30415 | 0.1 | LOC101928809 ART3 lnc-SDAD1-3-001 lnc-SDAD1-3-002 SDAD1 | ||
| GH04J076059 | Enhancer | 1.3 | FANTOM5 Ensembl ENCODE | 75.2 | +49.4 | 49421 | 4.8 | NCOR1 FOXA1 JUND RELA HES1 MEF2C RCOR1 REST TRIM22 TEAD1 | ART3 CXCL10 CXCL9 NAAA CXCL11 NUP54 SDAD1 LOC101928809 KR153194-147 piR-58297-350 | |
| GH04J076055 | Enhancer | 0.9 | Ensembl ENCODE | 74.8 | +44.0 | 44021 | 3.2 | EP300 JUND RELA RCOR1 TRIM22 BCL11A NFIC MEF2B NBN BATF | ART3 NAAA NUP54 CXCL10 CXCL9 SDAD1 LOC101928809 piR-58297-350 KR153194-147 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ART3 on UCSC Golden Path with GeneCards custom track
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ART3
- Top Transcription factor binding sites by QIAGEN in the ART3 gene promoter:
-
- AhR
- AML1a
- Cdc5
- FOXO3
- FOXO3b
- IRF-1
- IRF-2
- p53
Genomic Locations for ART3 Gene
Genomic Locations for ART3 Gene
- chr4:76,011,180-76,112,802
- (GRCh38/hg38)
- Size:
- 101,623 bases
- Orientation:
- Plus strand
- chr4:76,932,337-77,033,955
- (GRCh37/hg19)
- Size:
- 101,619 bases
- Orientation:
- Plus strand
Genomic View for ART3 Gene
Genes around ART3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4q21.1 by HGNC
- 4q21.1|4p15.1-p14 by Entrez Gene
- 4q21.1 by Ensembl
ART3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ART3 Gene
Proteins for ART3 Gene
-
Protein details for ART3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q13508-NAR3_HUMAN
- Recommended name:
- Ecto-ADP-ribosyltransferase 3
- Protein Accession:
- Q13508
- Q53XW3
- Q6FHT7
- Q8WVJ7
- Q93069
- Q96HL1
Protein attributes for ART3 Gene
- Size:
- 389 amino acids
- Molecular mass:
- 43923 Da
- Quaternary structure:
- No Data Available
Protein Expression for ART3 Gene
Post-translational modifications for ART3 Gene
Other Protein References for ART3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- XP_016863697.1
- NP_001364105.1
- NP_001170.2
- XP_016863699.1
- XP_024309824.1
- NP_001364102.1
- NP_001364112.1
- XP_024309823.1
- NP_001364107.1
- NP_001364104.1
- NP_001364114.1
- NP_001364109.1
- XP_024309822.1
- XP_024309821.1
- XP_024309831.1
- XP_024309827.1
- NP_001123489.1
- NP_001364111.1
- NP_001364106.1
- NP_001364108.1
- XP_016863695.1
- XP_024309829.1
- XP_024309819.1
- XP_024309820.1
- XP_024309830.1
- XP_024309826.1
- XP_024309825.1
- NP_001364103.1
- NP_001364113.1
- NP_001123488.1
- NP_001364110.1
- XP_024309828.1
- XP_024309818.1
Antibody Products
- LifeSpan BioSciences ART3 Monoclonal Antibody
- Creative Diagnostics Anti-ART3 monoclonal antibody, clone 4B3
- Creative Biolabs Recombinant Anti-Human ART3 Antibody
-
Custom Antibody ServicesOriGene Antibodies for ART3
- Novus Biologicals Antibodies for ART3
-
Abcam antibodies for ART3
- Invitrogen Antibodies for ART3 (AFLGC-ART3)
-
Biorbyt antibodies for ART3
-
Santa Cruz Biotechnology (SCBT) Antibodies for ART3
- Sino Biological Antibodies for ART3
Protein Products
-
OriGene Purified Proteins for ART3
- Search Origene for MassSpec and Protein Over-expression Lysates for ART3
- Origene Custom Protein Services for ART3
- Sino Biological Recombinant Proteins for ART3
- Sino Biological Cell Lysates for ART3
- antibodies-online: Show 5 available ART3 Proteins ranked by validation data
- Compare Top ART3 Proteins
-
Quality Products:
-
Signalway Proteins for ART3
-
Abcam proteins for ART3
Assay Products
- Creative Diagnostics Human ART3 ELISA Matched Antibody Pair
- Novus Biologicals ELISA Kits for ART3
- antibodies-online: Show 2 available ART3 Elisa Kits ranked by validation data
- Compare Top ART3 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for ART3 Gene
Domains & Families for ART3 Gene
Gene Families for ART3 Gene
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for ART3 Gene
Suggested Antigen Peptide Sequences for ART3 Gene
- GenScript: Design optimal peptide antigens:
-
- NAD(P)(+)--arginine ADP-ribosyltransferase 3 (NAR3_HUMAN)
- Mono-ADP-ribosyltransferase (Q5J1P8_HUMAN)
- Mono-ADP-ribosyltransferase (Q5J1Q0_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q13508- Family:
-
- Belongs to the Arg-specific ADP-ribosyltransferase family.
Function for ART3 Gene
Molecular function for ART3 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=L-arginyl-[protein] + NAD(+) = H(+) + N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide; Xref=Rhea:RHEA:19149, Rhea:RHEA-COMP:10532, Rhea:RHEA-COMP:15087, ChEBI:CHEBI:15378, ChEBI:CHEBI:17154, ChEBI:CHEBI:29965, ChEBI:CHEBI:57540, ChEBI:CHEBI:142554; EC=2.4.2.31;.
- GENATLAS Biochemistry:
- ADP-ribosyltransferase 3,expressed in testis
Enzyme Numbers (IUBMB) for ART3 Gene
Phenotypes From GWAS Catalog for ART3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003950 | NAD+ ADP-ribosyltransferase activity | IBA | 21873635 |
| GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity | IEA | -- |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0016757 | transferase activity, transferring glycosyl groups | IEA | -- |
Phenotypes for ART3 Gene
- MGI mutant phenotypes for ART3:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ART3:
-
- Decreased viability ratio
- Increased G2M DNA content, increased 8N DNA content
- Dynamic nuclei (hole, folded or small irregular)
- Decreased viability in esophageal squamous lineage
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Decreased human papilloma virus 16 (HPV16) pseudovirus infection
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ART3 - Select products 50% OFF >
- * ART3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ART3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ART3
- genomics-online: gRNA clones - Search results for available ART3 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for ART3
miRNA for ART3 Gene
- miRTarBase miRNAs that target ART3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ART3
- Browse OriGene Inhibitory RNA Products For ART3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ART3
- genomics-online: shRNA clones - Search results for available ART3 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for ART3 - Select products 50% OFF >
- * ART3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
- MG223250
- MR223250
- MR223250L3
- MR223250L4
- RC205011
- RC205011L3
- RC205011L4
- RC225558
- RC225558L3
- RC225558L4
- RC225592
- RC225592L1
- RC225592L2
- RC225592L3
- RC225592L4
- RG205011
- RG225558
- RG225592
- RR208006
- RR208006L3
- RR208006L4
- MR223250L3V
- MR223250L4V
- RC205011L3V
- RC205011L4V
- RC225558L3V
- RC225558L4V
- RC225592L1V
- RC225592L2V
- RC225592L3V
- RC225592L4V
- RR208006L3V
- RR208006L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for ART3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ART3
- genomics-online: cdna clones - Search results for available ART3 gene related products
- orf clones - Search results for available ART3 gene related products
Cell Line Products
-
Horizon Cell Lines for ART3
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ART3 Gene
Localization for ART3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ART3 Gene
- Cell membrane; Lipid-anchor, GPI-anchor.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 4 |
| endoplasmic reticulum | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| cytosol | 1 |
| golgi apparatus | 1 |
| peroxisome | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0031225 | anchored component of membrane | IEA | -- |
| GO:0031226 | intrinsic component of plasma membrane | TAS | 9119374 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for ART3 Gene
Pathways & Interactions for ART3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism of proteins | ||
| 2 | Post-translational modification- synthesis of GPI-anchored proteins | ||
| 3 | NAD metabolism |
NAD metabolism
.53
|
|
Pathways by source for ART3 Gene
3 Reactome pathways for ART3 Gene
1 GeneGo (Thomson Reuters) pathway for ART3 Gene
- NAD metabolism
Interacting Proteins for ART3 Gene
GPS-Prot Interaction Network for ART3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006471 | protein ADP-ribosylation | IBA,IEA | 21873635 |
| GO:0018120 | peptidyl-arginine ADP-ribosylation | IBA | 21873635 |
No data available for SIGNOR curated interactions for ART3 Gene
Drugs & Compounds for ART3 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for ART3 Gene
mRNA/cDNA for ART3 Gene
- 16 REFSEQ mRNAs :
- 27 NCBI additional mRNA sequence :
- 15 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000341029 1517 bps (ENST00000341029.9)
- ENST00000349321 1528 bps (ENST00000349321.7)
- ENST00000355810 1561 bps (ENST00000355810.8)
- ENST00000395688 323 bps (ENST00000395688.7)
- ENST00000504112 419 bps (ENST00000504112.5)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ART3 - Select products 50% OFF >
- * ART3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ART3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ART3
- genomics-online: gRNA clones - Search results for available ART3 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for ART3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ART3
- Browse OriGene Inhibitory RNA Products For ART3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ART3
- genomics-online: shRNA clones - Search results for available ART3 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for ART3 - Select products 50% OFF >
- * ART3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
- MG223250
- MR223250
- MR223250L3
- MR223250L4
- RC205011
- RC205011L3
- RC205011L4
- RC225558
- RC225558L3
- RC225558L4
- RC225592
- RC225592L1
- RC225592L2
- RC225592L3
- RC225592L4
- RG205011
- RG225558
- RG225592
- RR208006
- RR208006L3
- RR208006L4
- MR223250L3V
- MR223250L4V
- RC205011L3V
- RC205011L4V
- RC225558L3V
- RC225558L4V
- RC225592L1V
- RC225592L2V
- RC225592L3V
- RC225592L4V
- RR208006L3V
- RR208006L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for ART3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ART3
- genomics-online: cdna clones - Search results for available ART3 gene related products
- orf clones - Search results for available ART3 gene related products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||
| SP2: | - | - |
Relevant External Links for ART3 Gene
- GeneLoc Exon Structure for
- ART3
Expression for ART3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Bone (Muscoskeletal System)
- Adipose (Muscoskeletal System)
- Cartilage (Muscoskeletal System)
-
Peripheral Nervous System (Nervous System)
- Immature Schwann Cells Peripheral Nerve Domain
-
Testis (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for ART3 Gene
This gene is overexpressed in Muscle - Skeletal (x18.2), Heart - Left Ventricle (x7.5), Heart - Atrial Appendage (x6.0), and Testis (x5.4).
This gene is overexpressed in Ovary (29.3), Testis (25.4), and Serum (8.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ART3 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ART3
SOURCE GeneReport for Unigene cluster for ART3 Gene:
Hs.24976mRNA Expression by UniProt/SwissProt for ART3 Gene:
Q13508-NAR3_HUMAN
Tissue specificity:
Testis specific.
Evidence on tissue expression from TISSUES for ART3 Gene
- Muscle(4.5)
- Heart(2.1)
Primer Products
-
OriGene qPCR primer pairs for ART3
-
OriGene qPCR primer pairs and template standards for ART3
- genomics-online: primer clones - Search results for available ART3 gene related products
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for ART3 Gene
Orthologs for ART3 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ART3 31 30 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | ART3 31 30 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | ART3 31 30 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Art3 17 31 30 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Art3 30 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ART3 31 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ART3 31 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | art5 30 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | CABZ01019905.1 31 |
|
ManyToMany | |
| CR846080.3 31 |
|
ManyToMany | |||
| CR846080.5 31 |
|
ManyToMany | |||
| si:ch211-51i16.3 31 |
|
ManyToMany | |||
| CABZ01019905.2 31 |
|
ManyToMany | |||
| CABZ01064699.1 31 |
|
ManyToMany | |||
| BX908804.1 31 |
|
ManyToMany | |||
| si:ch73-379f5.5 31 |
|
ManyToMany | |||
| si:ch211-51i16.1 31 |
|
ManyToMany | |||
| CR846080.4 31 |
|
ManyToMany | |||
| art4 31 |
|
ManyToMany | |||
| si:ch211-163m16.7 31 |
|
ManyToMany | |||
| CABZ01019904.1 31 |
|
ManyToMany |
- Species where no ortholog for ART3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for ART3 Gene
- ENSEMBL:
- Gene Tree for ART3 (if available)
- TreeFam:
- Gene Tree for ART3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ART3: view image
Paralogs for ART3 Gene
(1) SIMAP similar genes for ART3 Gene using alignment to 8 proteins:
- NAR3_HUMAN
- E7ER42_HUMAN
- E7ESB3_HUMAN
- E7EX61_HUMAN
- E9PGR5_HUMAN
- Q5J1K9_HUMAN
- Q5J1P8_HUMAN
- Q5J1Q0_HUMAN
Pseudogenes.org Pseudogenes for ART3 Gene
Variants for ART3 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ART3 Gene
| SNP ID | Clinical significance and condition | Chr 04 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 731714 | Benign: not provided | 76,022,401(+) | G/T | SYNONYMOUS_VARIANT,INTRON_VARIANT | |
| 773454 | Benign: not provided | 76,022,794(+) | G/A | MISSENSE_VARIANT,INTRON_VARIANT | |
| rs1128864 | - | p.Ser363Leu | |||
| rs143599971 | - | p.Pro334Ser |
Residual Variation Intolerance Score:
60.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
8.71;
86.55% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ART3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ART3
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ART3 Gene
Disorders for ART3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| esophageal candidiasis |
|
|
| sciatic neuropathy |
|
|
Search ART3 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ART3
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for ART3 Gene
Publications for ART3 Gene
- Genome-wide expression of azoospermia testes demonstrates a specific profile and implicates ART3 in genetic susceptibility. (PMID: 18266473) Okada H … Inoue I (PLoS genetics 2008) 3 23 41 54
- Two novel human members of an emerging mammalian gene family related to mono-ADP-ribosylating bacterial toxins. (PMID: 9119374) Koch-Nolte F … Thiele HG (Genomics 1997) 2 3 4 54
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41 54
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 41 54
- Genomic organization and expression of the human mono-ADP-ribosyltransferase ART3 gene. (PMID: 16934346) Friedrich M … Hauschildt S (Biochimica et biophysica acta 2006) 3 23 54
ExternalLinks
Products for ART3 Gene
- Custom Antibody ServicesOriGene Antibodies for ART3
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ART3
- Search Origene for MassSpec and Protein Over-expression Lysates for ART3
- Origene Custom Protein Services for ART3
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ART3
- Browse OriGene Inhibitory RNA Products For ART3
- OriGene qPCR primer pairs for ART3
- OriGene qPCR primer pairs and template standards for ART3
- OriGene CRISPR knockouts for ART3
- MG223250
- MR223250
- MR223250L3
- MR223250L4
- RC205011
- RC205011L3
- RC205011L4
- RC225558
- RC225558L3
- RC225558L4
- RC225592
- RC225592L1
- RC225592L2
- RC225592L3
- RC225592L4
- RG205011
- RG225558
- RG225592
- RR208006
- RR208006L3
- RR208006L4
- MR223250L3V
- MR223250L4V
- RC205011L3V
- RC205011L4V
- RC225558L3V
- RC225558L4V
- RC225592L1V
- RC225592L2V
- RC225592L3V
- RC225592L4V
- RR208006L3V
- RR208006L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ART3
- Sino Biological Human cDNA Clone for ART3
- Sino Biological Recombinant Proteins for ART3
- Sino Biological Cell Lysates for ART3
- Sino Biological Antibodies for ART3
- Browse Sino Biological Assays
- Browse Recombinant Proteins
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for ART3
- Novus Biologicals proteins and lysates for ART3
- Novus Biologicals ELISA Kits for ART3
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for ART3
- Abcam proteins for ART3
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for ART3 (AFLGC-ART3)
- VectorBuilder Custom and pre-made DNA vectors for ART3 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for ART3 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for ART3 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for ART3 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for ART3
- antibodies-online: Show 34 available ART3 Antibodies ranked by validation data
- Compare Top ART3 Antibodies
- antibodies-online: Show 2 available ART3 Elisa Kits ranked by validation data
- Compare Top ART3 Elisa Kits
- Quality Products:
- antibodies-online: Show 5 available ART3 Proteins ranked by validation data
- Compare Top ART3 Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for ART3
- Search Santa Cruz Biotechnology (SCBT) for ART3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ART3
- Horizon Cell Lines for ART3
- genomics-online: cdna clones - Search results for available ART3 gene related products
- orf clones - Search results for available ART3 gene related products
- genomics-online: gRNA clones - Search results for available ART3 gene related products
- genomics-online: primer clones - Search results for available ART3 gene related products
- genomics-online: shRNA clones - Search results for available ART3 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ART3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ART3
- Search GeneCopoeia for miRNA 3'UTR Target clone products for ART3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ART3
- Biorbyt antibodies for ART3
- Search for ART3 ELISA kits at Signalway
- Signalway Proteins for ART3
Sources for ART3 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) H-invDB
- (47) HORDE
- (48) HUGE
- (49) IMGT
- (50) Leiden
- (51) miRBase
- (52) DME
- (53) OriGene
- (54) PubMed
- (55) R&D Systems
- (56) TGDB
- (57) Tocris
- (58) Abcam
- (59) Novus Biologicals
- (60) ProSpec
- (61) Sino Biological
- (62) GenScript
- (63) Qiagen
- (64) OCA
- (65) Proteopedia
- (66) MOPED
- (67) neXtProt
- (68) Reactome
- (69) GeneGo (Thomson Reuters)
- (70) DISEASES
- (71) SIMAP
- (72) GenomeRNAi
- (73) LifeMap
- (74) miRTarBase
- (75) MalaCards
- (76) Invitrogen
- (77) BitterDB
- (78) ESI-BIO
- (79) RefSeq
- (80) BioSystems
- (81) MaxQB
- (82) IUPHAR
- (83) BioGPS
- (84) Illumina
- (85) COMPARTMENTS
- (86) HOMER
- (87) PaxDb
- (88) ApexBio
- (89) Addgene
- (90) antibodies-online
- (91) CYP
- (92) NONCODE
- (93) TreeFam
- (94) PathCards
- (95) GeneReviews
- (96) GeneTex
- (97) Taconic Biosciences
- (98) GTEx
- (99) ProteomicsDB
- (100) SCBT
- (101) DGIdb
- (102) ClinicalTrials
- (103) RVIS
- (104) SIGNOR
- (105) diseasecard
- (106) NIH Rare Diseases
- (107) Orphanet
- (108) UMLS
- (109) GTR
- (110) Disease Ontology
- (111) Genetics Home Reference
- (112) MeSH
- (113) MedlinePlus
- (114) CDC
- (115) NINDS
- (116) NCBI Bookshelf
- (117) ClinVar
- (118) Gene Damage Index
- (119) HPO
- (120) UDN
- (121) VISTA
- (122) FANTOM5
- (123) ENCODE
- (124) ProSci
- (125) Horizon
- (126) The Signaling Pathways Project (SPP)
- (127) IID
- (128) VectorBuilder
- (129) SNPedia
- (130) BRCA Exchange
- (131) CIViC
- (132) ProteoGenix
- (133) dbSUPER
- (134) TISSUES
- (135) Gene ORGANizer
- (136) abm
- (137) Human Protein Atlas
- (138) GWAS Catalog
- (139) Monarch Initiative
- (140) DataMed
- (141) HumanCyc
- (142) genomics-online
- (143) UCNEbase
- (144) EPDnew
- (145) Applied Biosystems
- (146) GlyConnect
- (147) Aminode
- (148) GeneCopoeia
- (149) GPS-Prot
- (150) RNACentral
- (151) LncRNADisease
- (152) LOVD
- (153) miR2Disease
- (154) DiseaseEnhancer
- (155) Boster Bio
- (156) Biorbyt
- (157) Biocompare
- (158) Mastermind
- (159) CTD^2 Dashboard
- (160) CraniofacialAtlas
- (161) GeneImprint
- (162) Synthego
- (163) Bio Basic
- (164) ENA
- (165) GtRNAdb
- (166) LncBase
- (167) LncBook
- (168) LNCipedia
- (169) LncRNAdb
- (170) Modomics
- (171) PDBe
- (172) Rfam
- (173) SILVA
- (174) snOPY
- (175) SRPDB
- (176) GENCODE
- (177) TarBase
- (178) MyBioSource
- (179) Signalway Antibody