Aliases for ART1 Gene
External Ids for ART1 Gene
Previous GeneCards Identifiers for ART1 Gene
ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2. [provided by RefSeq, Jul 2008]
GeneCards Summary for ART1 Gene
ART1 (ADP-Ribosyltransferase 1) is a Protein Coding gene. Diseases associated with ART1 include Type 1 Diabetes Mellitus 4 and Retinitis Pigmentosa 19. Among its related pathways are NAD metabolism and Innate Immune System. Gene Ontology (GO) annotations related to this gene include NAD+ ADP-ribosyltransferase activity and NAD(P)+-protein-arginine ADP-ribosyltransferase activity. An important paralog of this gene is ART5.
UniProtKB/Swiss-Prot Summary for ART1 Gene
Has ADP-ribosyltransferase activity toward GLP1R.