Aliases for ARSJ Gene
External Ids for ARSJ Gene
Previous GeneCards Identifiers for ARSJ Gene
Sulfatases (EC 188.8.131.52), such as ARSJ, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules (Sardiello et al., 2005 [PubMed 16174644]).[supplied by OMIM, Mar 2008]
GeneCards Summary for ARSJ Gene
ARSJ (Arylsulfatase Family Member J) is a Protein Coding gene. Diseases associated with ARSJ include Rett Syndrome, Congenital Variant and Rett Syndrome. Among its related pathways are Gamma carboxylation, hypusine formation and arylsulfatase activation and Sphingolipid metabolism. Gene Ontology (GO) annotations related to this gene include sulfuric ester hydrolase activity and arylsulfatase activity. An important paralog of this gene is ARSI.