External Ids for ARRDC4 Gene
Previous GeneCards Identifiers for ARRDC4 Gene
GeneCards Summary for ARRDC4 Gene
ARRDC4 (Arrestin Domain Containing 4) is a Protein Coding gene. An important paralog of this gene is ARRDC3.
UniProtKB/Swiss-Prot for ARRDC4 Gene
Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (By similarity). Plays a role in endocytosis of activated G protein-coupled receptors (GPCRs) (Probable). Through an ubiquitination-dependent mechanism plays also a role in the incorporation of SLC11A2 into extracellular vesicles (By similarity). May play a role in glucose uptake (PubMed:19605364).