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Aliases for ARMH2 Gene

Aliases for ARMH2 Gene

  • Armadillo-Like Helical Domain Containing 2 2 3
  • Chromosome 6 Open Reading Frame 229 2 5
  • C6orf229 3 5
  • Uncharacterized Protein C6orf229 3

External Ids for ARMH2 Gene

Previous HGNC Symbols for ARMH2 Gene

  • C6orf229

Summaries for ARMH2 Gene

GeneCards Summary for ARMH2 Gene

ARMH2 (Armadillo-Like Helical Domain Containing 2) is a Protein Coding gene.

Additional gene information for ARMH2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARMH2 Gene

Genomics for ARMH2 Gene

GeneHancer (GH) Regulatory Elements for ARMH2 Gene

Promoters and enhancers for ARMH2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J024799 Enhancer 0.7 FANTOM5 650.7 -0.9 -885 0.4 HDAC1 MEIS2 SOX13 PKNOX1 AFF1 TFE3 NFIA RXRA SAP130 NR2F1 ARMH2 GMNN ALDH5A1 DCDC2 GPLD1 ENSG00000282804
GH06J024773 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 0.3 +22.8 22832 4.8 CLOCK MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 GMNN NUP50P2 ENSG00000272402 ARMH2
GH06J024803 Enhancer 0.8 ENCODE 0.7 -4.7 -4692 0.2 SOX13 FOXA2 SAP130 ZNF384 DNMT3B RARA TEAD3 SMARCC2 NR2F6 FOS RIPOR2 ARMH2 ENSG00000282804
GH06J024802 Enhancer 0.7 ENCODE 0.7 -4.0 -4011 0.4 SCRT1 SOX13 GATAD2A HLF CEBPB CEBPG HMG20A ZNF384 ETV5 TEAD3 C6orf62 ARMH2 ENSG00000282804
GH06J024778 Enhancer 0.8 ENCODE 0.4 +19.4 19417 1.3 ELF3 FOXA2 SMAD1 MLX ARID4B RARA YY1 ATF7 FOS MIXL1 C6orf62 GMNN ARMH2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ARMH2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ARMH2 Gene

Genomic Locations for ARMH2 Gene
chr6:24,797,321-24,798,896
(GRCh38/hg38)
Size:
1,576 bases
Orientation:
Minus strand
chr6:24,797,549-24,799,117
(GRCh37/hg19)

Genomic View for ARMH2 Gene

Genes around ARMH2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARMH2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARMH2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARMH2 Gene

Proteins for ARMH2 Gene

  • Protein details for ARMH2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H3BNL8-CF229_HUMAN
    Recommended name:
    Uncharacterized protein C6orf229
    Protein Accession:
    H3BNL8

    Protein attributes for ARMH2 Gene

    Size:
    230 amino acids
    Molecular mass:
    26547 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ARMH2 Gene

Post-translational modifications for ARMH2 Gene

No Post-translational modifications

Other Protein References for ARMH2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ARMH2 Gene

Domains & Families for ARMH2 Gene

Gene Families for ARMH2 Gene

Protein Domains for ARMH2 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ARMH2: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ARMH2 Gene

Function for ARMH2 Gene

Phenotypes From GWAS Catalog for ARMH2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ARMH2 Gene

Localization for ARMH2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ARMH2 Gene

Pathways & Interactions for ARMH2 Gene

SuperPathways for ARMH2 Gene

No Data Available

Interacting Proteins for ARMH2 Gene

Gene Ontology (GO) - Biological Process for ARMH2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ARMH2 Gene

Drugs & Compounds for ARMH2 Gene

No Compound Related Data Available

Transcripts for ARMH2 Gene

mRNA/cDNA for ARMH2 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ARMH2 Gene

No ASD Table

Relevant External Links for ARMH2 Gene

GeneLoc Exon Structure for
ARMH2
ECgene alternative splicing isoforms for
ARMH2

Expression for ARMH2 Gene

NURSA nuclear receptor signaling pathways regulating expression of ARMH2 Gene:

ARMH2
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ARMH2 Gene

Orthologs for ARMH2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ARMH2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC101057982 33
  • 99.28 (n)
dog
(Canis familiaris)
Mammalia LOC102152999 33
  • 81.01 (n)
C6orf229 34
  • 67 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC101904023 33
  • 80.49 (n)
rat
(Rattus norvegicus)
Mammalia LOC102548126 33
  • 66.82 (n)
mouse
(Mus musculus)
Mammalia 1700016G14Rik 33
  • 65.88 (n)
Armh2 16
oppossum
(Monodelphis domestica)
Mammalia C6orf229 34
  • 40 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C6orf229 34
  • 35 (a)
OneToOne
Species where no ortholog for ARMH2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ARMH2 Gene

ENSEMBL:
Gene Tree for ARMH2 (if available)
TreeFam:
Gene Tree for ARMH2 (if available)

Paralogs for ARMH2 Gene

No data available for Paralogs for ARMH2 Gene

Variants for ARMH2 Gene

Sequence variations from dbSNP and Humsavar for ARMH2 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000866145 -- 24,799,807(-) T/G upstream_transcript_variant
rs1000918408 -- 24,800,312(-) T/C upstream_transcript_variant
rs1001420887 -- 24,796,913(-) C/T downstream_transcript_variant
rs1003311780 -- 24,799,236(-) G/T upstream_transcript_variant
rs1004439993 -- 24,797,988(-) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ARMH2 Gene

Variant ID Type Subtype PubMed ID
nsv508396 CNV deletion 20534489
nsv5227 CNV deletion 18451855
nsv830609 CNV gain 17160897

Variation tolerance for ARMH2 Gene

Gene Damage Index Score: 5.34; 70.75% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ARMH2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ARMH2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARMH2 Gene

Disorders for ARMH2 Gene

Additional Disease Information for ARMH2

No disorders were found for ARMH2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARMH2 Gene

Publications for ARMH2 Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 4 58

Products for ARMH2 Gene

Sources for ARMH2 Gene

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