Aliases for ARMH1 Gene

Aliases for ARMH1 Gene

  • Armadillo Like Helical Domain Containing 1 2 3 5
  • P40 2 3 4
  • Armadillo-Like Helical Domain Containing Protein 1 3 4
  • NCRNA00082 3 4
  • C1orf228 3 4
  • Chromosome 1 Open Reading Frame 228 2
  • Uncharacterized Protein C1orf228 3
  • Non-Protein Coding RNA 82 2
  • MGC33556 2
  • ARMH1 5

External Ids for ARMH1 Gene

Previous HGNC Symbols for ARMH1 Gene

  • NCRNA00082
  • C1orf228

Summaries for ARMH1 Gene

GeneCards Summary for ARMH1 Gene

ARMH1 (Armadillo Like Helical Domain Containing 1) is a Protein Coding gene.

Additional gene information for ARMH1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ARMH1 Gene

Genomics for ARMH1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ARMH1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J044671 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 611.5 +0.3 345 6.5 CEBPG SP1 CREB1 GATAD2A CTCF PRDM10 ZNF629 REST TFE3 ZNF512 ARMH1 TMEM53 lnc-BEST4-2 MUTYH TOE1 ARTN RNU5F-1 NASP BTBD19 RPS8
GH01J044628 Promoter/Enhancer 1.9 Ensembl ENCODE CraniofacialAtlas dbSUPER 18.2 -43.2 -43213 6.6 ARHGAP35 HNRNPL PRDM10 ZNF629 TFE3 ZNF512 RFX1 ZNF692 POLR2A BACH1 lnc-TMEM53-2 piR-53648 TOE1 DMAP1 ARMH1 KDM4A MUTYH CCDC17 ARTN RNU5F-1
GH01J044694 Enhancer 0.8 Ensembl ENCODE 20.5 +20.5 20509 0.8 YY1 EED DPF2 RUNX3 GATAD2B BCLAF1 CBFB TCF12 IKZF1 RAD21 ARMH1 RNU5F-1 TMEM53 KIF2C
GH01J044641 Enhancer 0.9 Ensembl ENCODE dbSUPER 18.2 -29.9 -29881 6.4 POLR2A RBFOX2 SCRT2 CEBPB FOS YY1 BHLHE40 HNF4A RXRA GATA2 LOC107984950 ARMH1 RNU5F-1 ERI3 RF00017-190 TMEM53 lnc-BEST4-2 RNF220
GH01J044720 Promoter/Enhancer 1.6 Ensembl ENCODE dbSUPER 8.9 +46.9 46901 2.4 ARHGAP35 SP1 GATAD2A HNRNPL PRDM10 ZNF629 TFE3 RFX1 SIX5 LEF1 RNU5F-1 TOE1 MUTYH GPBP1L1 RPL7AP16 RPS8 DMAP1 HECTD3 RPS15AP10 NASP
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ARMH1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ARMH1

Genomic Locations for ARMH1 Gene

Genomic Locations for ARMH1 Gene
chr1:44,674,692-44,725,591
(GRCh38/hg38)
Size:
50,900 bases
Orientation:
Plus strand
chr1:45,140,364-45,191,263
(GRCh37/hg19)
Size:
50,900 bases
Orientation:
Plus strand

Genomic View for ARMH1 Gene

Genes around ARMH1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARMH1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARMH1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARMH1 Gene

Proteins for ARMH1 Gene

  • Protein details for ARMH1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PIY5-ARMD1_HUMAN
    Recommended name:
    Armadillo-like helical domain containing protein 1
    Protein Accession:
    Q6PIY5
    Secondary Accessions:
    • A1KXE5

    Protein attributes for ARMH1 Gene

    Size:
    440 amino acids
    Molecular mass:
    48855 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ARMH1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ARMH1 Gene

Post-translational modifications for ARMH1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ARMH1 Gene

Domains & Families for ARMH1 Gene

Gene Families for ARMH1 Gene

Protein Domains for ARMH1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ARMH1 Gene

GenScript: Design optimal peptide antigens:
  • p40 (CA228_HUMAN)
genes like me logo Genes that share domains with ARMH1: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ARMH1 Gene

Function for ARMH1 Gene

Phenotypes From GWAS Catalog for ARMH1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ARMH1 Gene

Localization for ARMH1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ARMH1 gene
Compartment Confidence
cytosol 3
nucleus 1
mitochondrion 0
peroxisome 0
endoplasmic reticulum 0

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ARMH1 Gene

Pathways & Interactions for ARMH1 Gene

PathCards logo

SuperPathways for ARMH1 Gene

No Data Available

Interacting Proteins for ARMH1 Gene

STRING Interaction Network Preview (showing top 1 STRING interactants - click image to see details)
STRING Interaction Network
Selected Interacting proteins: ENSP00000420716 Q6PIY5-ARMD1_HUMAN for ARMH1 Gene via STRING IID

Gene Ontology (GO) - Biological Process for ARMH1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ARMH1 Gene

Drugs & Compounds for ARMH1 Gene

No Compound Related Data Available

Transcripts for ARMH1 Gene

mRNA/cDNA for ARMH1 Gene

2 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :
21 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ARMH1 Gene

No ASD Table

Relevant External Links for ARMH1 Gene

GeneLoc Exon Structure for
ARMH1

Expression for ARMH1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ARMH1

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ARMH1 Gene

Orthologs for ARMH1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ARMH1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia C1H1orf228 30
  • 99.39 (n)
C1orf228 31
  • 98 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia C3H1orf228 30
  • 86.74 (n)
C1orf228 31
  • 82 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia C15H1orf228 30
  • 86.36 (n)
C1orf228 31
  • 81 (a)
OneToOne
Rat
(Rattus norvegicus)
Mammalia RGD1563714 30
  • 81.89 (n)
Mouse
(Mus musculus)
Mammalia Gm1661 30 31
  • 81.79 (n)
OneToOne
Armh1 17
Oppossum
(Monodelphis domestica)
Mammalia C1orf228 31
  • 61 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia C1orf228 31
  • 60 (a)
OneToOne
Chicken
(Gallus gallus)
Aves C8H1orf228 30
  • 64.58 (n)
C1orf228 31
  • 56 (a)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia C1orf228 31
  • 62 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia LOC101733444 30
  • 61.06 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.1749 30
Zebrafish
(Danio rerio)
Actinopterygii si:ch211-241d21.5 30
  • 60.92 (n)
C8H1orf228 31
  • 56 (a)
OneToOne
Dr.14941 30
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.8705 30
Sea Squirt
(Ciona savignyi)
Ascidiacea CSA.11040 31
  • 53 (a)
OneToOne
Species where no ortholog for ARMH1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for ARMH1 Gene

ENSEMBL:
Gene Tree for ARMH1 (if available)
TreeFam:
Gene Tree for ARMH1 (if available)

Paralogs for ARMH1 Gene

No data available for Paralogs for ARMH1 Gene

Variants for ARMH1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ARMH1 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
771308 Benign: not provided 44,701,011(+) C/T SYNONYMOUS_VARIANT
782974 Benign: not provided 44,724,145(+) G/A MISSENSE_VARIANT

Additional dbSNP identifiers (rs#s) for ARMH1 Gene

Structural Variations from Database of Genomic Variants (DGV) for ARMH1 Gene

Variant ID Type Subtype PubMed ID
esv2657051 CNV deletion 23128226
esv2662778 CNV deletion 23128226
esv3577830 CNV loss 25503493
esv3585889 CNV loss 21293372
esv3585890 CNV loss 21293372
esv3585891 CNV loss 21293372
nsv478963 CNV novel sequence insertion 20440878

Variation tolerance for ARMH1 Gene

Gene Damage Index Score: 1.39; 27.44% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ARMH1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ARMH1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARMH1 Gene

Disorders for ARMH1 Gene

No disorders were found for ARMH1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARMH1 Gene

Publications for ARMH1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3
  2. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4

Products for ARMH1 Gene

Sources for ARMH1 Gene