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Aliases for ARMH1 Gene

Aliases for ARMH1 Gene

  • Armadillo Like Helical Domain Containing 1 2 3
  • Armadillo-Like Helical Domain Containing Protein 1 3 4
  • NCRNA00082 3 4
  • C1orf228 3 4
  • P40 3 4
  • Armadillo-Like Helical Domain Containing 1 5
  • Chromosome 1 Open Reading Frame 228 2
  • Uncharacterized Protein C1orf228 3
  • Non-Protein Coding RNA 82 2

External Ids for ARMH1 Gene

Previous HGNC Symbols for ARMH1 Gene

  • NCRNA00082
  • C1orf228

Summaries for ARMH1 Gene

GeneCards Summary for ARMH1 Gene

ARMH1 (Armadillo Like Helical Domain Containing 1) is a Protein Coding gene.

Additional gene information for ARMH1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARMH1 Gene

Genomics for ARMH1 Gene

GeneHancer (GH) Regulatory Elements for ARMH1 Gene

Promoters and enhancers for ARMH1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J044671 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 611.5 +0.4 409 6.3 ZFX SP1 ELF3 CC2D1A CTCF MNT NKRF POLR2A MLLT1 CEBPG ARMH1 TMEM53 TOE1 MUTYH ARTN RNU5F-1 NASP KIF2C ENSG00000234329 BTBD19
GH01J044628 Promoter/Enhancer 2 Ensembl ENCODE dbSUPER 18.2 -43.1 -43144 6.7 HDGF ZFX ELF3 MNT CBFA2T2 NKRF POLR2A MLLT1 ZNF121 GTF2F1 PIR47647 TOE1 DMAP1 ARMH1 KDM4A MUTYH CCDC17 ARTN RNU5F-1 ERI3
GH01J044720 Promoter/Enhancer 1.8 Ensembl ENCODE dbSUPER 8.9 +46.9 46901 2.4 ZNF652 SP1 ELF3 ZKSCAN8 SIX5 CBFA2T2 ZNF148 NKRF POLR2A MLLT1 GC01M044722 RNU5F-1 TOE1 MUTYH GPBP1L1 ENSG00000234329 RPS8 DMAP1 HECTD3 RPS15AP10
GH01J044706 Enhancer 1.1 ENCODE dbSUPER 11.8 +32.7 32710 2.4 CC2D1A ELF3 CTCF ZNF121 SP1 PRDM1 RAD21 SMARCA4 IKZF1 POLR2A ARMH1 TMEM53 RNU5D-1 KIF2C RNF220 GC01P044699 GC01M044722 RNU5F-1 LOC105378690
GH01J044408 Promoter/Enhancer 1.7 UCNEbase Ensembl ENCODE dbSUPER 5.5 -266.0 -265991 2.2 PRDM1 RNF2 ZNF600 POLR2A ZBTB20 EZH2 ZBTB17 ZFHX2 ZNF664 SIN3A ARMH1 ATP6V0B RNF220 MIR5584
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ARMH1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ARMH1 Gene

Genomic Locations for ARMH1 Gene
chr1:44,674,692-44,725,591
(GRCh38/hg38)
Size:
50,900 bases
Orientation:
Plus strand
chr1:45,140,364-45,191,263
(GRCh37/hg19)
Size:
50,900 bases
Orientation:
Plus strand

Genomic View for ARMH1 Gene

Genes around ARMH1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARMH1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARMH1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARMH1 Gene

Proteins for ARMH1 Gene

  • Protein details for ARMH1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PIY5-ARMD1_HUMAN
    Recommended name:
    Armadillo-like helical domain containing protein 1
    Protein Accession:
    Q6PIY5
    Secondary Accessions:
    • A1KXE5

    Protein attributes for ARMH1 Gene

    Size:
    440 amino acids
    Molecular mass:
    48855 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ARMH1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ARMH1 Gene

Post-translational modifications for ARMH1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ARMH1 Gene

Domains & Families for ARMH1 Gene

Gene Families for ARMH1 Gene

Protein Domains for ARMH1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ARMH1 Gene

GenScript: Design optimal peptide antigens:
  • p40 (CA228_HUMAN)

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ARMH1: view

No data available for UniProtKB/Swiss-Prot for ARMH1 Gene

Function for ARMH1 Gene

Phenotypes From GWAS Catalog for ARMH1 Gene

Animal Model Products

Clone Products

  • Applied Biological Materials (abm): Clones for ARMH1 - Now 50% OFF >
  • * ARMH1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * ARMH1 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ARMH1 Gene

Localization for ARMH1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ARMH1 gene
Compartment Confidence
cytosol 3
nucleus 1
mitochondrion 0
peroxisome 0
endoplasmic reticulum 0

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ARMH1 Gene

Pathways & Interactions for ARMH1 Gene

PathCards logo

SuperPathways for ARMH1 Gene

No Data Available

Interacting Proteins for ARMH1 Gene

STRING Interaction Network Preview (showing top 1 STRING interactants - click image to see details)
https://version11.string-db.org/api/image/network?species=9606&limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000420716%0d9606.ENSP00000379845%0d
Selected Interacting proteins: ENSP00000420716 for ARMH1 Gene via STRING

Symbol External ID(s) Details
ABAT

Gene Ontology (GO) - Biological Process for ARMH1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ARMH1 Gene

Drugs & Compounds for ARMH1 Gene

No Compound Related Data Available

Transcripts for ARMH1 Gene

mRNA/cDNA for ARMH1 Gene

Clone Products

  • Applied Biological Materials (abm): Clones for ARMH1 - Now 50% OFF >
  • * ARMH1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * ARMH1 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

Alternative Splicing Database (ASD) splice patterns (SP) for ARMH1 Gene

No ASD Table

Relevant External Links for ARMH1 Gene

GeneLoc Exon Structure for
ARMH1
ECgene alternative splicing isoforms for
ARMH1

Expression for ARMH1 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ARMH1 Gene

Orthologs for ARMH1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ARMH1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf228 34
  • 99.39 (n)
C1orf228 35
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C3H1orf228 34
  • 86.74 (n)
C1orf228 35
  • 82 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C15H1orf228 34
  • 86.36 (n)
C1orf228 35
  • 81 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1563714 34
  • 81.89 (n)
mouse
(Mus musculus)
Mammalia Gm1661 35 34
  • 81.79 (n)
OneToOne
Armh1 17
oppossum
(Monodelphis domestica)
Mammalia C1orf228 35
  • 61 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C1orf228 35
  • 60 (a)
OneToOne
chicken
(Gallus gallus)
Aves C8H1orf228 34
  • 64.58 (n)
C1orf228 35
  • 56 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C1orf228 35
  • 62 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101733444 34
  • 61.06 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.1749 34
zebrafish
(Danio rerio)
Actinopterygii si:ch211-241d21.5 34
  • 60.92 (n)
C8H1orf228 35
  • 56 (a)
OneToOne
Dr.14941 34
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.8705 34
sea squirt
(Ciona savignyi)
Ascidiacea CSA.11040 35
  • 53 (a)
OneToOne
Species where no ortholog for ARMH1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ARMH1 Gene

ENSEMBL:
Gene Tree for ARMH1 (if available)
TreeFam:
Gene Tree for ARMH1 (if available)

Paralogs for ARMH1 Gene

No data available for Paralogs for ARMH1 Gene

Variants for ARMH1 Gene

Sequence variations from dbSNP and Humsavar for ARMH1 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000019955 -- 44,722,199(+) G/C coding_sequence_variant, genic_downstream_transcript_variant, intron_variant, missense_variant
rs1000081329 -- 44,703,396(+) G/A intron_variant
rs1000106877 -- 44,692,864(+) A/C intron_variant
rs1000171892 -- 44,707,696(+) A/G intron_variant
rs1000236594 -- 44,700,476(+) C/A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ARMH1 Gene

Variant ID Type Subtype PubMed ID
esv2657051 CNV deletion 23128226
esv2662778 CNV deletion 23128226
esv3577830 CNV loss 25503493
esv3585889 CNV loss 21293372
esv3585890 CNV loss 21293372
esv3585891 CNV loss 21293372
nsv478963 CNV novel sequence insertion 20440878

Variation tolerance for ARMH1 Gene

Gene Damage Index Score: 1.39; 27.44% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ARMH1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ARMH1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARMH1 Gene

Disorders for ARMH1 Gene

No disorders were found for ARMH1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARMH1 Gene

Publications for ARMH1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  3. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for ARMH1 Gene

Sources for ARMH1 Gene

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