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Aliases for ARMCX5-GPRASP2 Gene

Aliases for ARMCX5-GPRASP2 Gene

  • ARMCX5-GPRASP2 Readthrough 2 3 5
  • G-Protein Coupled Receptor-Associated Sorting Protein 2 3
  • ARMCX5-GPRASP2-BHLHB9-LINC00630 Readthrough 3
  • Transcription Regulator Of 60 KDa 3
  • ARMCX5-GPRASP2-BHLHB9-LINC00630 3
  • Protein BHLHb9 3
  • BHLHb9 3
  • P60TRP 3

External Ids for ARMCX5-GPRASP2 Gene

Previous GeneCards Identifiers for ARMCX5-GPRASP2 Gene

  • GC0XU901682
  • GC0XP101858

Summaries for ARMCX5-GPRASP2 Gene

Entrez Gene Summary for ARMCX5-GPRASP2 Gene

  • This locus represents naturally occurring readthrough transcription among the adjacent armadillo repeat containing, X-linked 5 (ARMCX5), G protein-coupled receptor associated sorting proteins 1 and 2 (GPRASP1 and GPRASP2), basic helix-loop-helix family member b9 (BHLHB9), and long intergenic non-protein coding RNA 630 (LINC00630) genes on chromosome X. Transcripts may make use of multiple alternative promoters and polyadenylation signals in this region. Readthrough transcripts may produce proteins identical to the proteins encoded by GPRASP2 or BHLHB9. [provided by RefSeq, Apr 2017]

GeneCards Summary for ARMCX5-GPRASP2 Gene

ARMCX5-GPRASP2 (ARMCX5-GPRASP2 Readthrough) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include amyloid-beta binding. An important paralog of this gene is GPRASP2.

Additional gene information for ARMCX5-GPRASP2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARMCX5-GPRASP2 Gene

Genomics for ARMCX5-GPRASP2 Gene

GeneHancer (GH) Regulatory Elements for ARMCX5-GPRASP2 Gene

Promoters and enhancers for ARMCX5-GPRASP2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XI102598 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 +0.5 453 2.4 PKNOX1 ATF1 ARID4B SIN3A DMAP1 ZNF48 YY1 POLR2B ZNF207 ZNF143 ARMCX5 ARMCX5-GPRASP2 GPRASP1 GPRASP2 ENSG00000227211 ENSG00000270050
GH0XI103151 Enhancer 1.2 Ensembl ENCODE 12.3 +553.0 552961 1.3 ARNT NEUROD1 FEZF1 GLI4 BRCA1 ZNF2 ZBTB7B TCF12 ZNF121 GLIS2 GPRASP1 BEX4 TCEAL3 ELF2P1 TMSB15B ZCCHC18 GPRASP2 BEX3 TCEAL7 TCEAL1
GH0XI102658 Promoter/Enhancer 1.7 FANTOM5 Ensembl ENCODE 0.2 +60.2 60151 2.6 CLOCK ATF1 FOXA2 ARID4B SIN3A YY1 FOS ATF7 MXD4 REST ENSG00000270050 GPRASP1 LINC00630 ARMCX5 ENSG00000239407 TCEAL3-AS1 TCEAL9 BHLHB9 ARMCX5-GPRASP2
GH0XI102650 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE 0.2 +52.6 52628 2.4 CTCF KLF1 ZNF76 RAD21 ZNF335 ZFHX2 ZBTB48 PATZ1 PRDM10 CHD2 GPRASP1 ENSG00000270050 ARMCX5-GPRASP2
GH0XI102711 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE 0.1 +113.7 113656 2.4 PKNOX1 ATF1 ZNF76 ZBTB7B RAD21 ZEB1 ZNF335 GLIS2 SCRT2 ATF7 GPRASP2 GC0XM102718 ARMCX5-GPRASP2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ARMCX5-GPRASP2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ARMCX5-GPRASP2 Gene

Genomic Locations for ARMCX5-GPRASP2 Gene
chrX:102,599,348-102,717,733
(GRCh38/hg38)
Size:
118,386 bases
Orientation:
Plus strand
chrX:101,854,276-101,972,661
(GRCh37/hg19)

Genomic View for ARMCX5-GPRASP2 Gene

Genes around ARMCX5-GPRASP2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARMCX5-GPRASP2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARMCX5-GPRASP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARMCX5-GPRASP2 Gene

Proteins for ARMCX5-GPRASP2 Gene

Post-translational modifications for ARMCX5-GPRASP2 Gene

No Post-translational modifications

Other Protein References for ARMCX5-GPRASP2 Gene

No data available for DME Specific Peptides for ARMCX5-GPRASP2 Gene

Domains & Families for ARMCX5-GPRASP2 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ARMCX5-GPRASP2 Gene

Function for ARMCX5-GPRASP2 Gene

Gene Ontology (GO) - Molecular Function for ARMCX5-GPRASP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001540 amyloid-beta binding IEA --
GO:0005515 protein binding IPI 21988832
GO:0042803 protein homodimerization activity ISS --
genes like me logo Genes that share ontologies with ARMCX5-GPRASP2: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ARMCX5-GPRASP2 Gene

Localization for ARMCX5-GPRASP2 Gene

Gene Ontology (GO) - Cellular Components for ARMCX5-GPRASP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA --
GO:0005829 cytosol IDA --
GO:0070062 extracellular exosome HDA 19056867
genes like me logo Genes that share ontologies with ARMCX5-GPRASP2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for ARMCX5-GPRASP2 Gene

Pathways & Interactions for ARMCX5-GPRASP2 Gene

SuperPathways for ARMCX5-GPRASP2 Gene

No Data Available

Interacting Proteins for ARMCX5-GPRASP2 Gene

Gene Ontology (GO) - Biological Process for ARMCX5-GPRASP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007611 learning or memory ISS --
GO:0043524 negative regulation of neuron apoptotic process ISS --
GO:0050769 positive regulation of neurogenesis ISS --
GO:0051965 positive regulation of synapse assembly ISS --
GO:0061003 positive regulation of dendritic spine morphogenesis ISS --
genes like me logo Genes that share ontologies with ARMCX5-GPRASP2: view

No data available for Pathways by source and SIGNOR curated interactions for ARMCX5-GPRASP2 Gene

Drugs & Compounds for ARMCX5-GPRASP2 Gene

No Compound Related Data Available

Transcripts for ARMCX5-GPRASP2 Gene

mRNA/cDNA for ARMCX5-GPRASP2 Gene

(4) REFSEQ mRNAs :
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for ARMCX5-GPRASP2 Gene

No ASD Table

Relevant External Links for ARMCX5-GPRASP2 Gene

GeneLoc Exon Structure for
ARMCX5-GPRASP2
ECgene alternative splicing isoforms for
ARMCX5-GPRASP2

Expression for ARMCX5-GPRASP2 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ARMCX5-GPRASP2 Gene

Orthologs for ARMCX5-GPRASP2 Gene

Evolution for ARMCX5-GPRASP2 Gene

ENSEMBL:
Gene Tree for ARMCX5-GPRASP2 (if available)
TreeFam:
Gene Tree for ARMCX5-GPRASP2 (if available)

No data available for Orthologs for ARMCX5-GPRASP2 Gene

Paralogs for ARMCX5-GPRASP2 Gene

Paralogs for ARMCX5-GPRASP2 Gene

genes like me logo Genes that share paralogs with ARMCX5-GPRASP2: view

Variants for ARMCX5-GPRASP2 Gene

Sequence variations from dbSNP and Humsavar for ARMCX5-GPRASP2 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1057518762 uncertain-significance, Intellectual disability 102,657,292(+) G/C intron_variant
rs1000029508 -- 102,658,663(+) G/A intron_variant
rs1000035861 -- 102,636,010(+) A/G intron_variant
rs1000064322 -- 102,643,910(+) A/T intron_variant
rs1000093258 -- 102,643,544(+) T/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ARMCX5-GPRASP2 Gene

Variant ID Type Subtype PubMed ID
nsv526716 CNV gain 19592680
nsv7017 CNV insertion 18451855

Additional Variant Information for ARMCX5-GPRASP2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ARMCX5-GPRASP2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ARMCX5-GPRASP2 Gene

Disorders for ARMCX5-GPRASP2 Gene

Additional Disease Information for ARMCX5-GPRASP2

No disorders were found for ARMCX5-GPRASP2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARMCX5-GPRASP2 Gene

Publications for ARMCX5-GPRASP2 Gene

  1. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. (PMID: 26871637) Yang X … Vidal M (Cell 2016) 3 58
  2. An inter-species protein-protein interaction network across vast evolutionary distance. (PMID: 27107014) Zhong Q … Vidal M (Molecular systems biology 2016) 3 58
  3. Widespread macromolecular interaction perturbations in human genetic disorders. (PMID: 25910212) Sahni N … Vidal M (Cell 2015) 3 58
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  5. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J … Yang X (Molecular systems biology 2011) 3 58

Products for ARMCX5-GPRASP2 Gene

Sources for ARMCX5-GPRASP2 Gene

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