Aliases for ARMC7 Gene
External Ids for ARMC7 Gene
- HGNC: 26168
- Entrez Gene: 79637
- Ensembl: ENSG00000125449
- UniProtKB: Q9H6L4
Previous GeneCards Identifiers for ARMC7 Gene
- GC17P070617
- GC17P073106
- GC17P068515
Summaries for ARMC7 Gene
GeneCards Summary for ARMC7 Gene
ARMC7 (Armadillo Repeat Containing 7) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include binding.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARMC7 Gene
Genomics for ARMC7 Gene
GeneHancer (GH) Regulatory Elements for ARMC7 Gene
Promoters and enhancers for ARMC7 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around ARMC7 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the ARMC7 gene promoter:
-
- Cart-1
- Lmo2
- TGIF
- GATA-3
- GATA-2
- GATA-1
- Elk-1
- HNF-4alpha1
- HNF-4alpha2
- c-Jun
Regulatory Element Products
Genomic Locations for ARMC7 Gene
Genomic Locations for ARMC7 Gene
- chr17:75,109,952-75,130,265
- (GRCh38/hg38)
- Size:
- 20,314 bases
- Orientation:
- Plus strand
- chr17:73,106,047-73,126,360
- (GRCh37/hg19)
- Size:
- 20,314 bases
- Orientation:
- Plus strand
Genomic View for ARMC7 Gene
Genes around ARMC7 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q25.1 by Entrez Gene
- 17q25.1 by HGNC
- 17q25.1 by Ensembl
ARMC7 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ARMC7 Gene
Proteins for ARMC7 Gene
-
Protein details for ARMC7 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9H6L4-ARMC7_HUMAN
- Recommended name:
- Armadillo repeat-containing protein 7
- Protein Accession:
- Q9H6L4
- B4DVA4
Protein attributes for ARMC7 Gene
- Size:
- 198 amino acids
- Molecular mass:
- 21924 Da
- Quaternary structure:
- No Data Available
Protein Expression for ARMC7 Gene
Post-translational modifications for ARMC7 Gene
Other Protein References for ARMC7 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ARMC7
- Invitrogen Antibodies for ARMC7 (AFLGC-ARMC7)
- Search GeneTex for Antibodies for ARMC7
-
Boster Bio Antibodies for ARMC7
-
Santa Cruz Biotechnology (SCBT) Antibodies for ARMC7
Protein Products
-
OriGene Purified Proteins for ARMC7
- Search Origene for MassSpec and Protein Over-expression Lysates for ARMC7
- Origene Custom Protein Services for ARMC7
- Search GeneTex for Proteins for ARMC7
Assay Products
No data available for DME Specific Peptides for ARMC7 Gene
Domains & Families for ARMC7 Gene
Gene Families for ARMC7 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for ARMC7 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ARMC7 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for ARMC7 Gene
Function for ARMC7 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 16189514 |
| GO:0019903 | protein phosphatase binding | IBA | -- |
| GO:0045294 | alpha-catenin binding | IBA | -- |
| GO:0045296 | cadherin binding | IBA | -- |
Phenotypes for ARMC7 Gene
- MGI mutant phenotypes for ARMC7:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ARMC7:
Animal Models for ARMC7 Gene
- MGI Knock Outs for ARMC7:
-
- Armc7 Armc7<tm1.1(KOMP)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ARMC7
-
CRISPR Products
-
OriGene CRISPR knockouts for ARMC7
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ARMC7
- genomics-online: gRNA clones - Search results for 108 available ARMC7 gene related products
- Overview of 108 available ARMC7 gene related products
- Applied Biological Materials CRISPR for ARMC7
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ARMC7
- GenScript: Design CRISPR guide RNA sequences for ARMC7
miRNA for ARMC7 Gene
- miRTarBase miRNAs that target ARMC7
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ARMC7
- Browse OriGene Inhibitory RNA Products For ARMC7
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ARMC7
- genomics-online: shRNA clones - Search results for 108 available ARMC7 gene related products
- Overview of 108 available ARMC7 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ARMC7
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ARMC7
- Applied Biological Materials Clones for ARMC7
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ARMC7 Gene
Localization for ARMC7 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| plasma membrane | 3 |
| cytosol | 3 |
| extracellular | 1 |
| peroxisome | 1 |
- Cytosol (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | -- |
| GO:0005737 | cytoplasm | IBA | -- |
| GO:0016342 | catenin complex | IBA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for ARMC7 Gene
Pathways & Interactions for ARMC7 Gene
No Data Available
Interacting Proteins for ARMC7 Gene
Selected Interacting proteins:
Q9H6L4-ARMC7_HUMAN
ENSP00000245543
for ARMC7 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for ARMC7
No data available for Pathways by source and SIGNOR curated interactions for ARMC7 Gene
Transcripts for ARMC7 Gene
mRNA/cDNA for ARMC7 Gene
- (4) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (163) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000581078 1002 bps (uc010wru.2)
- ENST00000582136 1204 bps (uc060jtb.1)
- ENST00000245543 2126 bps (uc002jmw.1)
- ENST00000584947 445 bps (uc060jtc.1)
- ENST00000579096 1122 bps (uc010dga.2)
Unigene Clusters for ARMC7 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ARMC7
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ARMC7
- genomics-online: gRNA clones - Search results for 108 available ARMC7 gene related products
- Overview of 108 available ARMC7 gene related products
- Applied Biological Materials CRISPR for ARMC7
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ARMC7
- GenScript: Design CRISPR guide RNA sequences for ARMC7
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ARMC7
- Browse OriGene Inhibitory RNA Products For ARMC7
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ARMC7
- genomics-online: shRNA clones - Search results for 108 available ARMC7 gene related products
- Overview of 108 available ARMC7 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ARMC7
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ARMC7
- Applied Biological Materials Clones for ARMC7
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | · | 3e | ^ | 4 | ^ | 5a | · | 5b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||
| SP2: | - | - | - | - | - | ||||||||||||||||||
| SP3: | |||||||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||||
| SP5: | - |
Expression for ARMC7 Gene
mRNA differential expression in normal tissues according to GTEx for ARMC7 Gene
This gene is overexpressed in Kidney - Cortex (x5.3) and Whole Blood (x4.8).
This gene is overexpressed in Neutrophil (32.4), Tlymphocyte (17.4), Heart (10.7), and Monocytes (8.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ARMC7 Gene
NURSA nuclear receptor signaling pathways regulating expression of ARMC7 Gene:
ARMC7SOURCE GeneReport for Unigene cluster for ARMC7 Gene:
Hs.413047Evidence on tissue expression from TISSUES for ARMC7 Gene
- Intestine(4.1)
- Skin(4.1)
- Nervous system(2.9)
Primer Products
-
OriGene qPCR primer pairs for ARMC7
-
OriGene qPCR primer pairs and template standards for ARMC7
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ARMC7 Gene
Orthologs for ARMC7 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ARMC7 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | ARMC7 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | ARMC7 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Armc7 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Armc7 16 34 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| oppossum (Monodelphis domestica) |
Mammalia | ARMC7 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ARMC7 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | ARMC7 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | armc7 33 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.6511 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | armc7 34 33 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | CG14881 34 |
|
OneToOne | |
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT5G37290 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.10883 34 |
|
OneToOne |
- Species where no ortholog for ARMC7 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for ARMC7 Gene
- ENSEMBL:
- Gene Tree for ARMC7 (if available)
- TreeFam:
- Gene Tree for ARMC7 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ARMC7: view image
Paralogs for ARMC7 Gene
No data available for Paralogs for ARMC7 Gene
Variants for ARMC7 Gene
| SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000015816 | -- | 75,129,287(+) | G/T | 3_prime_UTR_variant, genic_downstream_transcript_variant | |
| rs1000076548 | -- | 75,118,520(+) | C/T | genic_downstream_transcript_variant, intron_variant | |
| rs1000143309 | -- | 75,108,021(+) | TT/ | upstream_transcript_variant | |
| rs1000249494 | -- | 75,128,051(+) | T/A | genic_downstream_transcript_variant, intron_variant | |
| rs1000256299 | -- | 75,124,305(+) | G/A | genic_downstream_transcript_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2663217 | CNV | deletion | 23128226 |
| esv3554782 | CNV | deletion | 23714750 |
| esv3641258 | CNV | loss | 21293372 |
| esv3641259 | CNV | loss | 21293372 |
| esv3641260 | CNV | loss | 21293372 |
| nsv470602 | CNV | loss | 18288195 |
Residual Variation Intolerance Score:
64.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.37;
42.02% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ARMC7 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ARMC7
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARMC7 Gene
Disorders for ARMC7 Gene
Additional Disease Information for ARMC7
No disorders were found for ARMC7 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARMC7 Gene
Publications for ARMC7 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
- Pooled-matrix protein interaction screens using Barcode Fusion Genetics. (PMID: 27107012) Yachie N … Roth FP (Molecular systems biology 2016) 3 58
Products for ARMC7 Gene
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- Invitrogen Antibodies for ARMC7 (AFLGC-ARMC7)
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- antibodies-online: Search results for available ARMC7 related products ranked by validation data
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- Overview of 108 available ARMC7 gene related products
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- genomics-online: primer clones - Search results for 108 available ARMC7 gene related products
- Overview of 108 available ARMC7 gene related products
- genomics-online: shRNA clones - Search results for 108 available ARMC7 gene related products
- Overview of 108 available ARMC7 gene related products
- Browse GeneCopoeia Cell Lines
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Sources for ARMC7 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt