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Aliases for ARMC7 Gene

Aliases for ARMC7 Gene

  • Armadillo Repeat Containing 7 2 3 5
  • Armadillo Repeat-Containing Protein 7 3

External Ids for ARMC7 Gene

Previous GeneCards Identifiers for ARMC7 Gene

  • GC17P070617
  • GC17P073106
  • GC17P068515

Summaries for ARMC7 Gene

GeneCards Summary for ARMC7 Gene

ARMC7 (Armadillo Repeat Containing 7) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include binding.

Additional gene information for ARMC7 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARMC7 Gene

Genomics for ARMC7 Gene

GeneHancer (GH) Regulatory Elements for ARMC7 Gene

Promoters and enhancers for ARMC7 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J075109 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 657.5 +0.1 99 2 ARID4B SIN3A ZNF48 GTF3C2 ELK1 ARID2 ZNF143 ZNF207 KLF7 ATF7 ARMC7 NUP85 GGA3 UNK NT5C ENSG00000266980 H3F3B JPT1 SRP68 ATP5PD
GH17J074461 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 10.7 -644.2 -644183 9.3 HDGF PKNOX1 FOXA2 SMAD1 ZFP64 YBX1 IRF4 ZNF766 ZNF207 ZNF143 CD300A NUP85 NAT9 NT5C GGA3 MGC16275 GPR142 CD300LB ARMC7 BTBD17
GH17J074281 Enhancer 1.5 FANTOM5 Ensembl ENCODE 10.7 -827.1 -827148 1.8 HDGF ATF1 SMAD1 TCF12 ZNF766 GLIS2 FOS ATF7 RUNX3 SP3 CD300E TTYH2 NAT9 GGA3 ARMC7 NUP85 ENSG00000270993 NT5C DNAI2 CD300C
GH17J074960 Enhancer 1.4 Ensembl ENCODE dbSUPER 10.8 -148.7 -148718 1.5 HDGF CLOCK FOXA2 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 TSEN54 ARMC7 HID1 MRPL58 GC17M074966 OTOP3
GH17J075085 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 5 -18.5 -18456 11.9 CLOCK MLX ZFP64 YBX1 YY1 SLC30A9 ZNF143 ZNF263 MCM3 SP3 SLC16A5 ENSG00000206713 GC17M075090 UNK NUP85 NT5C ENSG00000267342 ENSG00000266980 GGA3 NAT9
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ARMC7 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ARMC7 gene promoter:
  • Cart-1
  • Lmo2
  • TGIF
  • GATA-3
  • GATA-2
  • GATA-1
  • Elk-1
  • HNF-4alpha1
  • HNF-4alpha2
  • c-Jun

Genomic Locations for ARMC7 Gene

Genomic Locations for ARMC7 Gene
20,314 bases
Plus strand
20,314 bases
Plus strand

Genomic View for ARMC7 Gene

Genes around ARMC7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARMC7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARMC7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARMC7 Gene

Proteins for ARMC7 Gene

  • Protein details for ARMC7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Armadillo repeat-containing protein 7
    Protein Accession:
    Secondary Accessions:
    • B4DVA4

    Protein attributes for ARMC7 Gene

    198 amino acids
    Molecular mass:
    21924 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ARMC7 Gene


neXtProt entry for ARMC7 Gene

Post-translational modifications for ARMC7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ARMC7 Gene

Antibody Products

  • Boster Bio Antibodies for ARMC7
  • Santa Cruz Biotechnology (SCBT) Antibodies for ARMC7

No data available for DME Specific Peptides for ARMC7 Gene

Domains & Families for ARMC7 Gene

Gene Families for ARMC7 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ARMC7 Gene

Suggested Antigen Peptide Sequences for ARMC7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ARMC7: view

No data available for UniProtKB/Swiss-Prot for ARMC7 Gene

Function for ARMC7 Gene

Gene Ontology (GO) - Molecular Function for ARMC7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
GO:0019903 protein phosphatase binding IBA --
GO:0045294 alpha-catenin binding IBA --
GO:0045296 cadherin binding IBA --
genes like me logo Genes that share ontologies with ARMC7: view
genes like me logo Genes that share phenotypes with ARMC7: view

Animal Models for ARMC7 Gene

MGI Knock Outs for ARMC7:
  • Armc7 Armc7<tm1.1(KOMP)Wtsi>

Animal Model Products

miRNA for ARMC7 Gene

miRTarBase miRNAs that target ARMC7

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ARMC7 Gene

Localization for ARMC7 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ARMC7 gene
Compartment Confidence
nucleus 4
plasma membrane 3
cytosol 3
extracellular 1
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ARMC7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
GO:0005737 cytoplasm IBA --
GO:0016342 catenin complex IBA --
genes like me logo Genes that share ontologies with ARMC7: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ARMC7 Gene

Pathways & Interactions for ARMC7 Gene

SuperPathways for ARMC7 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ARMC7 Gene


No data available for Pathways by source and SIGNOR curated interactions for ARMC7 Gene

Drugs & Compounds for ARMC7 Gene

No Compound Related Data Available

Transcripts for ARMC7 Gene

Unigene Clusters for ARMC7 Gene

Armadillo repeat containing 7:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ARMC7 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c · 3d · 3e ^ 4 ^ 5a · 5b
SP1: - - - - - -
SP2: - - - - -
SP4: - - -
SP5: -

Relevant External Links for ARMC7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ARMC7 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ARMC7 Gene

mRNA differential expression in normal tissues according to GTEx for ARMC7 Gene

This gene is overexpressed in Kidney - Cortex (x5.3) and Whole Blood (x4.8).

Protein differential expression in normal tissues from HIPED for ARMC7 Gene

This gene is overexpressed in Neutrophil (32.4), Tlymphocyte (17.4), Heart (10.7), and Monocytes (8.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ARMC7 Gene

Protein tissue co-expression partners for ARMC7 Gene

NURSA nuclear receptor signaling pathways regulating expression of ARMC7 Gene:


SOURCE GeneReport for Unigene cluster for ARMC7 Gene:


Evidence on tissue expression from TISSUES for ARMC7 Gene

  • Intestine(4.1)
  • Skin(4.1)
  • Nervous system(2.9)
genes like me logo Genes that share expression patterns with ARMC7: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ARMC7 Gene

Orthologs for ARMC7 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ARMC7 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ARMC7 34 33
  • 98.99 (n)
(Canis familiaris)
Mammalia ARMC7 34
  • 87 (a)
(Bos Taurus)
Mammalia ARMC7 34 33
  • 86.97 (n)
(Rattus norvegicus)
Mammalia Armc7 33
  • 84.26 (n)
(Mus musculus)
Mammalia Armc7 16 34 33
  • 84.09 (n)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 75 (a)
-- 34
  • 52 (a)
(Monodelphis domestica)
Mammalia ARMC7 34
  • 73 (a)
(Gallus gallus)
Aves ARMC7 34 33
  • 70.56 (n)
(Anolis carolinensis)
Reptilia ARMC7 34
  • 66 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia armc7 33
  • 65.07 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.6511 33
(Danio rerio)
Actinopterygii armc7 34 33
  • 63.45 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG14881 34
  • 18 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G37290 33
  • 51.85 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10883 34
  • 43 (a)
Species where no ortholog for ARMC7 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ARMC7 Gene

Gene Tree for ARMC7 (if available)
Gene Tree for ARMC7 (if available)
Evolutionary constrained regions (ECRs) for ARMC7: view image

Paralogs for ARMC7 Gene

No data available for Paralogs for ARMC7 Gene

Variants for ARMC7 Gene

Sequence variations from dbSNP and Humsavar for ARMC7 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000015816 -- 75,129,287(+) G/T 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1000076548 -- 75,118,520(+) C/T genic_downstream_transcript_variant, intron_variant
rs1000143309 -- 75,108,021(+) TT/ upstream_transcript_variant
rs1000249494 -- 75,128,051(+) T/A genic_downstream_transcript_variant, intron_variant
rs1000256299 -- 75,124,305(+) G/A genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ARMC7 Gene

Variant ID Type Subtype PubMed ID
esv2663217 CNV deletion 23128226
esv3554782 CNV deletion 23714750
esv3641258 CNV loss 21293372
esv3641259 CNV loss 21293372
esv3641260 CNV loss 21293372
nsv470602 CNV loss 18288195

Variation tolerance for ARMC7 Gene

Residual Variation Intolerance Score: 64.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.37; 42.02% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ARMC7 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARMC7 Gene

Disorders for ARMC7 Gene

Additional Disease Information for ARMC7

No disorders were found for ARMC7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARMC7 Gene

Publications for ARMC7 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  5. Pooled-matrix protein interaction screens using Barcode Fusion Genetics. (PMID: 27107012) Yachie N … Roth FP (Molecular systems biology 2016) 3 58

Products for ARMC7 Gene

Sources for ARMC7 Gene

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