Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ARMC1 Gene

Aliases for ARMC1 Gene

  • Armadillo Repeat Containing 1 2 3 5
  • Armadillo Repeat-Containing Protein 1 3
  • Arcp 3
  • ARCP 4

External Ids for ARMC1 Gene

Previous GeneCards Identifiers for ARMC1 Gene

  • GC08M066677
  • GC08M066515
  • GC08M062004

Summaries for ARMC1 Gene

GeneCards Summary for ARMC1 Gene

ARMC1 (Armadillo Repeat Containing 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include binding.

Additional gene information for ARMC1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARMC1 Gene

Genomics for ARMC1 Gene

GeneHancer (GH) Regulatory Elements for ARMC1 Gene

Promoters and enhancers for ARMC1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J065632 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 661.3 -0.2 -166 2.8 PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 IRF4 YY1 POLR2B ZNF143 ARMC1 MTFR1 ENSG00000272010
GH08J065643 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 5.9 -10.3 -10302 2.7 HDGF PKNOX1 SMAD1 ARID4B SIN3A ZBTB7B YY1 SLC30A9 POLR2B ZNF766 MTFR1 ENSG00000272010 ARMC1 ENSG00000272155
GH08J066151 Enhancer 0.6 dbSUPER 10 -518.2 -518219 1.1 ZBTB11 ZFP64 ZC3H11A ZNF623 ZNF781 ZNF518A ZNF697 SCRT2 CRH ENSG00000250869 TRIM55 ARMC1 LINC00967 GC08P066170 PIR59286 GC08P066148 GC08P066152 GC08P066013
GH08J065732 Enhancer 0.4 dbSUPER 4.4 -99.7 -99728 2.2 JUND PRDM10 MTFR1 ENSG00000272010 ARMC1 GC08M065706 GC08P065773 PDE7A
GH08J065636 Enhancer 0.8 ENCODE 0.7 -2.7 -2667 1.4 PKNOX1 CLOCK NEUROD1 SIN3A RFX5 FOS RCOR1 USF2 CEBPB GATAD2B ENSG00000272010 MTFR1 ARMC1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ARMC1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ARMC1 gene promoter:

Genomic Locations for ARMC1 Gene

Genomic Locations for ARMC1 Gene
chr8:65,602,456-65,634,217
(GRCh38/hg38)
Size:
31,762 bases
Orientation:
Minus strand
chr8:66,514,691-66,546,452
(GRCh37/hg19)

Genomic View for ARMC1 Gene

Genes around ARMC1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARMC1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARMC1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARMC1 Gene

Proteins for ARMC1 Gene

  • Protein details for ARMC1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NVT9-ARMC1_HUMAN
    Recommended name:
    Armadillo repeat-containing protein 1
    Protein Accession:
    Q9NVT9
    Secondary Accessions:
    • B4E2W7
    • Q9H018
    • Q9H820

    Protein attributes for ARMC1 Gene

    Size:
    282 amino acids
    Molecular mass:
    31281 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ARMC1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ARMC1 Gene

Post-translational modifications for ARMC1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ARMC1 Gene

Domains & Families for ARMC1 Gene

Gene Families for ARMC1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ARMC1 Gene

Suggested Antigen Peptide Sequences for ARMC1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ARMC1: view

No data available for UniProtKB/Swiss-Prot for ARMC1 Gene

Function for ARMC1 Gene

Phenotypes From GWAS Catalog for ARMC1 Gene

Gene Ontology (GO) - Molecular Function for ARMC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ARMC1: view
genes like me logo Genes that share phenotypes with ARMC1: view

Animal Model Products

miRNA for ARMC1 Gene

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ARMC1 Gene

Localization for ARMC1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ARMC1 gene
Compartment Confidence
nucleus 4
mitochondrion 3
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ARMC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
GO:0005737 cytoplasm IBA --
GO:0005739 mitochondrion IEA --
genes like me logo Genes that share ontologies with ARMC1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ARMC1 Gene

Pathways & Interactions for ARMC1 Gene

SuperPathways for ARMC1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ARMC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030001 metal ion transport IEA --
genes like me logo Genes that share ontologies with ARMC1: view

No data available for Pathways by source and SIGNOR curated interactions for ARMC1 Gene

Drugs & Compounds for ARMC1 Gene

No Compound Related Data Available

Transcripts for ARMC1 Gene

mRNA/cDNA for ARMC1 Gene

Unigene Clusters for ARMC1 Gene

Armadillo repeat containing 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ARMC1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8
SP1: - -
SP2: -
SP3: - - -
SP4: -
SP5: - - -

Relevant External Links for ARMC1 Gene

GeneLoc Exon Structure for
ARMC1
ECgene alternative splicing isoforms for
ARMC1

Expression for ARMC1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ARMC1 Gene

Protein differential expression in normal tissues from HIPED for ARMC1 Gene

This gene is overexpressed in Skin (7.2) and Bone marrow stromal cell (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ARMC1 Gene



Protein tissue co-expression partners for ARMC1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ARMC1 Gene:

ARMC1

SOURCE GeneReport for Unigene cluster for ARMC1 Gene:

Hs.269542

Evidence on tissue expression from TISSUES for ARMC1 Gene

  • Lymph node(4.2)
  • Stomach(4.2)
  • Nervous system(3.8)
genes like me logo Genes that share expression patterns with ARMC1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ARMC1 Gene

Orthologs for ARMC1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ARMC1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ARMC1 34 33
  • 99.88 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ARMC1 34
  • 96 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ARMC1 34
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ARMC1 34 33
  • 92.91 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Armc1 33
  • 91.47 (n)
cow
(Bos Taurus)
Mammalia ARMC1 34 33
  • 90.9 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Armc1 16 34 33
  • 90.07 (n)
chicken
(Gallus gallus)
Aves ARMC1 34 33
  • 83.51 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ARMC1 34
  • 92 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia armc1 33
  • 77.45 (n)
Str.20051 33
African clawed frog
(Xenopus laevis)
Amphibia LOC398519 33
zebrafish
(Danio rerio)
Actinopterygii armc1 34 33
  • 71.29 (n)
OneToOne
sbcb398 33
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8431 34
  • 34 (a)
OneToOne
Species where no ortholog for ARMC1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ARMC1 Gene

ENSEMBL:
Gene Tree for ARMC1 (if available)
TreeFam:
Gene Tree for ARMC1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ARMC1: view image

Paralogs for ARMC1 Gene

Pseudogenes.org Pseudogenes for ARMC1 Gene

genes like me logo Genes that share paralogs with ARMC1: view

No data available for Paralogs for ARMC1 Gene

Variants for ARMC1 Gene

Sequence variations from dbSNP and Humsavar for ARMC1 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1000137589 -- 65,616,252(-) C/T intron_variant
rs1000170801 -- 65,616,361(-) C/T intron_variant
rs1000184683 -- 65,602,110(-) T/G downstream_transcript_variant
rs1000222022 -- 65,627,468(-) G/A intron_variant
rs1000378783 -- 65,623,901(-) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ARMC1 Gene

Variant ID Type Subtype PubMed ID
esv2761434 CNV gain 21179565
nsv398101 CNV deletion 16902084
nsv398351 CNV deletion 16902084

Variation tolerance for ARMC1 Gene

Residual Variation Intolerance Score: 53.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.68; 14.48% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ARMC1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ARMC1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARMC1 Gene

Disorders for ARMC1 Gene

Additional Disease Information for ARMC1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for ARMC1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARMC1 Gene

Publications for ARMC1 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
  2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson SL … O'Brien SJ (PloS one 2010) 3 44 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58

Products for ARMC1 Gene

Sources for ARMC1 Gene

Content
Loading form....