Free for academic non-profit institutions. Other users need a Commercial license
ARL8A (ADP Ribosylation Factor Like GTPase 8A) is a Protein Coding gene. Diseases associated with ARL8A include Drug-Induced Lupus Erythematosus. Among its related pathways are Innate Immune System. Gene Ontology (GO) annotations related to this gene include GTP binding and obsolete signal transducer activity. An important paralog of this gene is ARL8B.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000166 | nucleotide binding | IEA | -- |
GO:0003924 | GTPase activity | NAS | 15331635 |
GO:0005515 | protein binding | IPI | 24955142 |
GO:0005525 | GTP binding | IEA,IDA | 15331635 |
GO:0043014 | alpha-tubulin binding | ISS | 15331635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005737 | cytoplasm | IEA,IDA | 15331635 |
GO:0005764 | lysosome | IEA | -- |
GO:0005765 | lysosomal membrane | IBA | 21873635 |
GO:0005768 | endosome | IEA | -- |
GO:0005774 | vacuolar membrane | IBA | 21873635 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Innate Immune System |
.61
|
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007049 | cell cycle | IEA | -- |
GO:0007059 | chromosome segregation | ISS | 14871887 |
GO:0008089 | anterograde axonal transport | IEA | -- |
GO:0015031 | protein transport | IEA | -- |
GO:0043312 | neutrophil degranulation | TAS | -- |
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
ManyToMany | |
Chimpanzee (Pan troglodytes) |
Mammalia | ARL8A 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Arl8a 30 |
|
||
Cow (Bos Taurus) |
Mammalia | ARL8A 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Arl8a 30 17 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | ARL8A 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | -- 31 |
|
ManyToMany | |
ARL8A 30 |
|
||||
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | arl8a 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | arl8a 30 31 |
|
ManyToMany | |
Fruit Fly (Drosophila melanogaster) |
Insecta | Gie 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | arl-8 30 31 |
|
OneToMany | |
Thale Cress (Arabidopsis thaliana) |
eudicotyledons | ARLA1D 30 |
|
||
Rice (Oryza sativa) |
Liliopsida | Os03g0200800 30 |
|
||
Wheat (Triticum aestivum) |
Liliopsida | Ta.3262 30 |
|
||
Bread mold (Neurospora crassa) |
Ascomycetes | NCU08618 30 |
|
Disorder | Aliases | PubMed IDs |
---|---|---|
drug-induced lupus erythematosus |
|
|