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ARL5C (ADP Ribosylation Factor Like GTPase 5C) is a Protein Coding gene. Diseases associated with ARL5C include Usher Syndrome, Type If and Renal Cell Carcinoma, Papillary, 1. Gene Ontology (GO) annotations related to this gene include GTP binding. An important paralog of this gene is ARL5B.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000166 | nucleotide binding | IEA | -- |
GO:0005525 | GTP binding | IEA,IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005737 | cytoplasm | IBA | 21873635 |
GO:0005802 | trans-Golgi network | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006886 | intracellular protein transport | IBA | 21873635 |
GO:0016192 | vesicle-mediated transport | IBA | 21873635 |
GO:1903292 | protein localization to Golgi membrane | IBA | 21873635 |
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Guanosine triphosphate | Experimental | Pharma | 0 |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | ARL5C 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | ARL5C 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | LOC787781 30 |
|
||
ARL5C 31 |
|
OneToOne | |||
Mouse (Mus musculus) |
Mammalia | Arl5c 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Arl5c 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
ManyToMany | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
ManyToMany | |
Lizard (Anolis carolinensis) |
Reptilia | ARL5C 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | arl5b 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | arl5c 30 31 |
|
OneToOne | |
Fruit Fly (Drosophila melanogaster) |
Insecta | CG7197 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | arl-5 30 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.10998 31 |
|
ManyToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2671727 | CNV | deletion | 23128226 |
esv3640539 | CNV | loss | 21293372 |
esv3893011 | CNV | loss | 25118596 |
nsv1146669 | OTHER | inversion | 26484159 |
nsv833440 | CNV | loss | 17160897 |
nsv833441 | CNV | loss | 17160897 |
Disorder | Aliases | PubMed IDs |
---|---|---|
usher syndrome, type if |
|
|
renal cell carcinoma, papillary, 1 |
|
|