Aliases for ARL4A Gene
External Ids for ARL4A Gene
Previous HGNC Symbols for ARL4A Gene
Previous GeneCards Identifiers for ARL4A Gene
ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for ARL4A Gene
ARL4A (ADP Ribosylation Factor Like GTPase 4A) is a Protein Coding gene. Among its related pathways are Mesodermal Commitment Pathway. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is ARL4C.
UniProtKB/Swiss-Prot Summary for ARL4A Gene
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form.