Aliases for ARHGEF19 Gene
External Ids for ARHGEF19 Gene
Previous GeneCards Identifiers for ARHGEF19 Gene
Guanine nucleotide exchange factors (GEFs) such as ARHGEF19 accelerate the GTPase activity of Rho GTPases (see RHOA, MIM 165390).[supplied by OMIM, Dec 2008]
GeneCards Summary for ARHGEF19 Gene
ARHGEF19 (Rho Guanine Nucleotide Exchange Factor 19) is a Protein Coding gene. Diseases associated with ARHGEF19 include Osteopathia Striata With Cranial Sclerosis. Among its related pathways are Signaling by GPCR and p75 NTR receptor-mediated signalling. Gene Ontology (GO) annotations related to this gene include GTPase activator activity and Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is ARHGEF5.
UniProtKB/Swiss-Prot Summary for ARHGEF19 Gene
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase.