Aliases for ARHGEF10L Gene
External Ids for ARHGEF10L Gene
Previous GeneCards Identifiers for ARHGEF10L Gene
This gene belongs to the RhoGEF subfamily of RhoGTPases. Members of this subfamily are activated by specific guanine nucleotide exchange factors (GEFs) and are involved in signal transduction. The encoded protein shows cytosolic distribution. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2016]
GeneCards Summary for ARHGEF10L Gene
ARHGEF10L (Rho Guanine Nucleotide Exchange Factor 10 Like) is a Protein Coding gene. Among its related pathways are p75 NTR receptor-mediated signalling and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is ARHGEF10.
UniProtKB/Swiss-Prot for ARHGEF10L Gene
Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC.