Aliases for ARHGAP5 Gene
External Ids for ARHGAP5 Gene
Previous HGNC Symbols for ARHGAP5 Gene
Previous GeneCards Identifiers for ARHGAP5 Gene
Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for ARHGAP5 Gene
ARHGAP5 (Rho GTPase Activating Protein 5) is a Protein Coding gene. Diseases associated with ARHGAP5 include Capillary Disease. Among its related pathways are G-protein signaling RAC1 in cellular process and G-protein signaling_Regulation of CDC42 activity. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activator activity. An important paralog of this gene is ARHGAP35.
UniProtKB/Swiss-Prot for ARHGAP5 Gene
GTPase-activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of RASA1/p120GAP.