Aliases for ARHGAP33 Gene
External Ids for ARHGAP33 Gene
Previous HGNC Symbols for ARHGAP33 Gene
Previous GeneCards Identifiers for ARHGAP33 Gene
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Alternative splice variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]
GeneCards Summary for ARHGAP33 Gene
ARHGAP33 (Rho GTPase Activating Protein 33) is a Protein Coding gene. Diseases associated with ARHGAP33 include Noma. Among its related pathways are Signaling by GPCR and p75 NTR receptor-mediated signalling. Gene Ontology (GO) annotations related to this gene include GTPase activator activity and phosphatidylinositol binding. An important paralog of this gene is ARHGAP32.
UniProtKB/Swiss-Prot Summary for ARHGAP33 Gene
May be involved in several stages of intracellular trafficking. Could play an important role in the regulation of glucose transport by insulin. May act as a downstream effector of RHOQ/TC10 in the regulation of insulin-stimulated glucose transport (By similarity).