Aliases for ARHGAP31 Gene
Aliases for ARHGAP31 Gene
External Ids for ARHGAP31 Gene
- HGNC: 29216
- Entrez Gene: 57514
- Ensembl: ENSG00000031081
- OMIM: 610911
- UniProtKB: Q2M1Z3
Previous GeneCards Identifiers for ARHGAP31 Gene
- GC03P119013
- GC03P116388
Summaries for ARHGAP31 Gene
-
This gene encodes a GTPase-activating protein (GAP). A variety of cellular processes are regulated by Rho GTPases which cycle between an inactive form bound to GDP and an active form bound to GTP. This cycling between inactive and active forms is regulated by guanine nucleotide exchange factors and GAPs. The encoded protein is a GAP shown to regulate two GTPases involved in protein trafficking and cell growth. [provided by RefSeq, Jul 2008]
GeneCards Summary for ARHGAP31 Gene
ARHGAP31 (Rho GTPase Activating Protein 31) is a Protein Coding gene. Diseases associated with ARHGAP31 include Adams-Oliver Syndrome 1 and Adams-Oliver Syndrome. Among its related pathways are G-protein signaling_Regulation of CDC42 activity and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include GTPase activator activity and SH3 domain binding. An important paralog of this gene is ARHGAP32.
UniProtKB/Swiss-Prot for ARHGAP31 Gene
-
Functions as a GTPase-activating protein (GAP) for RAC1 and CDC42. Required for cell spreading, polarized lamellipodia formation and cell migration.
Additional gene information for ARHGAP31 Gene
- Monarch Initiative
- Search for ARHGAP31 at DataMed
- Search for ARHGAP31 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARHGAP31 Gene
Genomics for ARHGAP31 Gene
GeneHancer (GH) Regulatory Elements for ARHGAP31 Gene
Promoters and enhancers for ARHGAP31 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ARHGAP31 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for ARHGAP31 Gene
Genomic Locations for ARHGAP31 Gene
- chr3:119,294,289-119,420,714
- (GRCh38/hg38)
- Size:
- 126,426 bases
- Orientation:
- Plus strand
- chr3:119,013,220-119,139,561
- (GRCh37/hg19)
Genomic View for ARHGAP31 Gene
Genes around ARHGAP31 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3q13.32 by Ensembl
- 3q13.32-q13.33 by Entrez Gene
- 3q13.32-q13.33 by HGNC
ARHGAP31 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ARHGAP31 Gene
Proteins for ARHGAP31 Gene
-
Protein details for ARHGAP31 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q2M1Z3-RHG31_HUMAN
- Recommended name:
- Rho GTPase-activating protein 31
- Protein Accession:
- Q2M1Z3
- Q9ULL6
Protein attributes for ARHGAP31 Gene
- Size:
- 1444 amino acids
- Molecular mass:
- 156985 Da
- Quaternary structure:
-
- Interacts with ITSN1, which inhibits GAP activity. Interacts with PARVA (By similarity). Interacts with GTP-loaded RHOU.
- SequenceCaution:
-
- Sequence=BAA86518.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for ARHGAP31 Gene
Post-translational modifications for ARHGAP31 Gene
- Phosphorylation on Thr-789 reduces GAP activity.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for ARHGAP31 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ARHGAP31
- Invitrogen Antibodies for ARHGAP31
- Search GeneTex for Antibodies for ARHGAP31
-
Santa Cruz Biotechnology (SCBT) Antibodies for ARHGAP31
Protein Products
-
OriGene Purified Proteins for ARHGAP31
- Search Origene for MassSpec and Protein Over-expression Lysates for ARHGAP31
- Origene Custom Protein Services for ARHGAP31
- Search GeneTex for Proteins for ARHGAP31
Assay Products
No data available for DME Specific Peptides for ARHGAP31 Gene
Domains & Families for ARHGAP31 Gene
Gene Families for ARHGAP31 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Predicted intracellular proteins
Protein Domains for ARHGAP31 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ARHGAP31 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for ARHGAP31 Gene
Function for ARHGAP31 Gene
Molecular function for ARHGAP31 Gene
- UniProtKB/Swiss-Prot Function:
- Functions as a GTPase-activating protein (GAP) for RAC1 and CDC42. Required for cell spreading, polarized lamellipodia formation and cell migration.
Phenotypes From GWAS Catalog for ARHGAP31 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | TAS | -- |
| GO:0017124 | SH3 domain binding | IEA | -- |
Phenotypes for ARHGAP31 Gene
- GenomeRNAi human phenotypes for ARHGAP31:
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for ARHGAP31 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ARHGAP31 gene
- Search ViGene Biosciences for ARHGAP31
CRISPR Products
-
OriGene CRISPR knockouts for ARHGAP31
- genomics-online: gRNA clones - Search results for 129 available ARHGAP31 gene related products
- Overview of 129 available ARHGAP31 gene related products
- Applied Biological Materials CRISPR for ARHGAP31
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ARHGAP31
- GenScript: Design CRISPR guide RNA sequences for ARHGAP31
miRNA for ARHGAP31 Gene
- miRTarBase miRNAs that target ARHGAP31
-
- hsa-mir-6770-3p (MIRT494692)
- hsa-mir-6825-5p (MIRT494693)
- hsa-mir-4730 (MIRT494694)
- hsa-mir-6883-5p (MIRT494695)
- hsa-mir-6785-5p (MIRT494696)
- hsa-mir-4728-5p (MIRT494697)
- hsa-mir-7106-5p (MIRT494698)
- hsa-mir-149-3p (MIRT494699)
- hsa-mir-8085 (MIRT494700)
- hsa-mir-6731-5p (MIRT494701)
- hsa-mir-663a (MIRT494702)
- hsa-mir-6787-5p (MIRT494703)
- hsa-mir-1908-5p (MIRT494704)
- hsa-mir-6797-5p (MIRT494705)
- hsa-mir-1249-5p (MIRT494706)
- hsa-mir-765 (MIRT494707)
- hsa-mir-4706 (MIRT494708)
- hsa-mir-4749-5p (MIRT494709)
- hsa-mir-6133 (MIRT494710)
- hsa-mir-6130 (MIRT494711)
- hsa-mir-6129 (MIRT494712)
- hsa-mir-6127 (MIRT494713)
- hsa-mir-4510 (MIRT494714)
- hsa-mir-4419a (MIRT494715)
- hsa-mir-4784 (MIRT494716)
- hsa-mir-3150b-3p (MIRT494717)
- hsa-mir-6889-5p (MIRT494718)
- hsa-mir-6777-5p (MIRT494719)
- hsa-mir-4756-5p (MIRT494720)
- hsa-mir-4739 (MIRT494721)
- hsa-mir-1321 (MIRT494722)
- hsa-mir-6873-5p (MIRT494723)
- hsa-mir-6760-5p (MIRT494724)
- hsa-mir-3680-3p (MIRT660535)
- hsa-mir-576-5p (MIRT660536)
- hsa-mir-33b-5p (MIRT660537)
- hsa-mir-33a-5p (MIRT660538)
- hsa-mir-4735-5p (MIRT660539)
- hsa-mir-133a-5p (MIRT790106)
- hsa-mir-138-5p (MIRT790112)
- hsa-mir-3189-5p (MIRT790262)
- hsa-mir-3692-5p (MIRT790341)
- hsa-mir-4758-3p (MIRT790616)
- hsa-mir-544a (MIRT790730)
- hsa-mir-548q (MIRT790749)
- hsa-mir-5699-5p (MIRT790784)
- hsa-mir-6071 (MIRT790805)
- hsa-mir-6131 (MIRT790827)
- hsa-mir-6738-3p (MIRT790908)
- hsa-mir-6828-3p (MIRT791002)
- hsa-mir-93-3p (MIRT791163)
miRNA Products
- Search ViGene Biosciences for ARHGAP31
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- genomics-online: shRNA clones - Search results for 129 available ARHGAP31 gene related products
- Overview of 129 available ARHGAP31 gene related products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for ARHGAP31
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for ARHGAP31
-
ViGene Biosciences adenoviral particle packaged cDNA for ARHGAP31 gene
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ViGene Biosciences lentiviral particle packaged cDNA for ARHGAP31 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ARHGAP31 gene
No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ARHGAP31 Gene
Localization for ARHGAP31 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ARHGAP31 Gene
- Cell projection, lamellipodium. Cell junction, focal adhesion.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| nucleus | 3 |
| cytoskeleton | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | TAS | -- |
| GO:0005925 | focal adhesion | IEA | -- |
| GO:0030027 | lamellipodium | IBA | -- |
| GO:0030054 | cell junction | IEA | -- |
| GO:0042995 | cell projection | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for ARHGAP31 Gene
Pathways & Interactions for ARHGAP31 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cytoskeletal Signaling | ||
| 2 | p75 NTR receptor-mediated signalling |
.36
|
|
| 3 | Signaling by GPCR | ||
| 4 | Signaling by Rho GTPases | ||
| 5 | G-protein signaling_Regulation of CDC42 activity | ||
Pathways by source for ARHGAP31 Gene
3 Reactome pathways for ARHGAP31 Gene
1 GeneGo (Thomson Reuters) pathway for ARHGAP31 Gene
1 Cell Signaling Technology pathway for ARHGAP31 Gene
Interacting Proteins for ARHGAP31 Gene
Selected Interacting proteins:
Q2M1Z3-RHG31_HUMAN
ENSP00000264245
for ARHGAP31 Gene via
IID
STRING
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007264 | small GTPase mediated signal transduction | IBA,IEA | -- |
| GO:0043547 | positive regulation of GTPase activity | IEA | -- |
| GO:0051056 | regulation of small GTPase mediated signal transduction | TAS | -- |
No data available for SIGNOR curated interactions for ARHGAP31 Gene
Transcripts for ARHGAP31 Gene
mRNA/cDNA for ARHGAP31 Gene
- (3) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (90) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ARHGAP31 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ARHGAP31
- genomics-online: gRNA clones - Search results for 129 available ARHGAP31 gene related products
- Overview of 129 available ARHGAP31 gene related products
- Applied Biological Materials CRISPR for ARHGAP31
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ARHGAP31
- GenScript: Design CRISPR guide RNA sequences for ARHGAP31
miRNA Products
- Search ViGene Biosciences for ARHGAP31
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for ARHGAP31
- Browse OriGene Inhibitory RNA Products For ARHGAP31
- genomics-online: shRNA clones - Search results for 129 available ARHGAP31 gene related products
- Overview of 129 available ARHGAP31 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ARHGAP31 gene
Clone Products
-
OriGene ORF clones in human for ARHGAP31
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for ARHGAP31
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ARHGAP31
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for ARHGAP31
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for ARHGAP31 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Surface Ectoderm (Integumentary System)
- Surface Ectoderm Cells Surface Ectoderm
- Surface Ectoderm
- Endothelium (Cardiovascular System)
-
Ectoderm (Gastrulation Derivatives)
- Surface Ectoderm Cells Surface Ectoderm
-
Epidermis (Integumentary System)
- Surface Ectoderm Cells Surface Ectoderm
- NULL (Uncategorized)
-
Lung (Respiratory System)
This gene is overexpressed in Esophagus (22.2), Pancreas (15.9), and CD8 Tcells (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ARHGAP31 Gene
NURSA nuclear receptor signaling pathways regulating expression of ARHGAP31 Gene:
ARHGAP31SOURCE GeneReport for Unigene cluster for ARHGAP31 Gene:
Hs.668218Evidence on tissue expression from TISSUES for ARHGAP31 Gene
- Nervous system(4.5)
- Liver(4.2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for ARHGAP31 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- endocrine
- integumentary
- nervous
- reproductive
- respiratory
- skeletal muscle
- skeleton
- urinary
Regions:
Head and neck:
- brain
- cerebellum
- cerebrospinal fluid
- chin
- cranial nerve
- ear
- eye
- eyelid
- face
- forehead
- head
- jaw
- lip
- mandible
- maxilla
- meninges
- mouth
- nose
- outer ear
- scalp
- skull
Thorax:
- aorta
- breast
- chest wall
- heart
- heart valve
- lung
- rib
- rib cage
- sternum
Abdomen:
- abdominal wall
Pelvis:
- placenta
- uterus
Limb:
- ankle
- digit
- finger
- foot
- hand
- lower limb
- nail
- toe
- upper limb
General:
- blood
- blood vessel
- hair
- peripheral nervous system
- skin
Primer Products
-
OriGene qPCR primer pairs for ARHGAP31
- genomics-online: primer clones - Search results for 129 available ARHGAP31 gene related products
- Overview of 129 available ARHGAP31 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ARHGAP31 Gene
Orthologs for ARHGAP31 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ARHGAP31 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | ARHGAP31 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | ARHGAP31 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Arhgap31 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Arhgap31 33 16 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ARHGAP31 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ARHGAP31 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | ARHGAP31 34 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | arhgap31 34 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | CdGAPr 34 |
|
OneToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | RGD1 34 |
|
OneToMany |
- Species where no ortholog for ARHGAP31 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for ARHGAP31 Gene
Paralogs for ARHGAP31 Gene
(20) SIMAP similar genes for ARHGAP31 Gene using alignment to 2 proteins:
Variants for ARHGAP31 Gene
| SNP ID | Clin | Chr 03 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs10049221 | likely-benign, Adams-Oliver syndrome | 119,382,285(+) | A/G | intron_variant | |
| rs1024165125 | uncertain-significance, Adams-Oliver syndrome | 119,294,462(+) | C/G | 5_prime_UTR_variant | |
| rs1045215834 | uncertain-significance, Adams-Oliver syndrome | 119,418,374(+) | G/A | 3_prime_UTR_variant, genic_downstream_transcript_variant | |
| rs113918185 | likely-benign, Adams-Oliver syndrome | 119,417,483(+) | C/T | 3_prime_UTR_variant | |
| rs11391882 | benign, Adams-Oliver syndrome | 119,417,250(+) | /C | 3_prime_UTR_variant |
Residual Variation Intolerance Score:
44.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.23;
52.49% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ARHGAP31 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARHGAP31 Gene
Disorders for ARHGAP31 Gene
(4) MalaCards diseases for ARHGAP31 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| adams-oliver syndrome 1 |
|
|
| adams-oliver syndrome |
|
|
| oliver syndrome |
|
|
| aplasia cutis congenita |
|
|
Search ARHGAP31 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
RHG31_HUMAN- Adams-Oliver syndrome 1 (AOS1) [MIM:100300]: A disorder characterized by the congenital absence of skin (aplasia cutis congenita) in combination with transverse limb defects. Aplasia cutis congenita can be located anywhere on the body, but in the vast majority of the cases, it is present on the posterior parietal region where it is often associated with an underlying defect of the parietal bones. Limb abnormalities are typically limb truncation defects affecting the distal phalanges or entire digits (true ectrodactyly). Only rarely, metatarsals/metacarpals or more proximal limb structures are also affected. Apart from transverse limb defects, syndactyly, most commonly of second and third toes, can also be observed. The clinical features are highly variable and can also include cardiovascular malformations, brain abnormalities and vascular defects such as cutis marmorata and dilated scalp veins. {ECO:0000269 PubMed:21565291}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for ARHGAP31
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for ARHGAP31 Gene
Publications for ARHGAP31 Gene
- The human orthologue of CdGAP is a phosphoprotein and a GTPase-activating protein for Cdc42 and Rac1 but not RhoA. (PMID: 16519628) Tcherkezian J … Lamarche-Vane N (Biology of the cell 2006) 2 3 4 22 58
- Gain-of-function mutations of ARHGAP31, a Cdc42/Rac1 GTPase regulator, cause syndromic cutis aplasia and limb anomalies. (PMID: 21565291) Southgate L … Trembath RC (American journal of human genetics 2011) 3 4 58
- Multiple common variants for celiac disease influencing immune gene expression. (PMID: 20190752) Dubois PC … van Heel DA (Nature genetics 2010) 3 44 58
- GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2. (PMID: 12819203) Zhao C … Feng GS (The Journal of biological chemistry 2003) 2 3 58
- Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10574462) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1999) 3 4 58
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- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for ARHGAP31
- VectorBuilder custom plasmid, inducible vectors for ARHGAP31
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ARHGAP31
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 131 available SAE1 Antibodies ranked by validation data
- Compare Top SAE1 Antibodies
- antibodies-online: Search results for available SAE1 related products ranked by validation data
- antibodies-online: Search results for available SAE1 related products ranked by validation data
- Search GeneTex for Antibodies for ARHGAP31
- Search GeneTex for Proteins for ARHGAP31
- ViGene Biosciences adenoviral particle packaged cDNA for ARHGAP31 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ARHGAP31 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ARHGAP31 gene
- Search ViGene Biosciences for ARHGAP31
- Santa Cruz Biotechnology (SCBT) Antibodies for ARHGAP31
- Search Santa Cruz Biotechnology (SCBT) for ARHGAP31 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ARHGAP31
- Horizon Cell Lines for ARHGAP31
- genomics-online: cdna clones - Search results for 129 available SAE1 gene related products
- Overview of 129 available SAE1 gene related products
- orf clones - Search results for 129 available SAE1 gene related products
- Overview of 129 available SAE1 gene related products
- genomics-online: gRNA clones - Search results for 129 available SAE1 gene related products
- Overview of 129 available SAE1 gene related products
- genomics-online: primer clones - Search results for 129 available SAE1 gene related products
- Overview of 129 available SAE1 gene related products
- genomics-online: shRNA clones - Search results for 129 available SAE1 gene related products
- Overview of 129 available SAE1 gene related products
Sources for ARHGAP31 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems