Aliases for ARHGAP25 Gene
External Ids for ARHGAP25 Gene
Previous GeneCards Identifiers for ARHGAP25 Gene
ARHGAPs, such as ARHGAP25, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).[supplied by OMIM, Mar 2008]
GeneCards Summary for ARHGAP25 Gene
ARHGAP25 (Rho GTPase Activating Protein 25) is a Protein Coding gene. Among its related pathways are p75 NTR receptor-mediated signalling and Signaling by Rho GTPases. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is ARHGAP22.
UniProtKB/Swiss-Prot for ARHGAP25 Gene
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.