Aliases for ARHGAP19 Gene
External Ids for ARHGAP19 Gene
Previous GeneCards Identifiers for ARHGAP19 Gene
Members of the ARHGAP family, such as ARHGAP19, encode negative regulators of Rho GTPases (see RHOA; MIM 165390), which are involved in cell migration, proliferation, and differentiation, actin remodeling, and G1 cell cycle progression (Lv et al., 2007 [PubMed 17454002]).[supplied by OMIM, Mar 2008]
GeneCards Summary for ARHGAP19 Gene
ARHGAP19 (Rho GTPase Activating Protein 19) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and p75 NTR receptor-mediated signalling. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is ARHGAP19-SLIT1.
UniProtKB/Swiss-Prot Summary for ARHGAP19 Gene
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.