Aliases for ARHGAP11B Gene
External Ids for ARHGAP11B Gene
Previous HGNC Symbols for ARHGAP11B Gene
Previous GeneCards Identifiers for ARHGAP11B Gene
GeneCards Summary for ARHGAP11B Gene
ARHGAP11B (Rho GTPase Activating Protein 11B) is a Protein Coding gene. Diseases associated with ARHGAP11B include Chromosome 15Q13.3 Deletion Syndrome and Pyromania. Among its related pathways are Signaling by GPCR and p75 NTR receptor-mediated signalling. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is ARHGAP11A.
UniProtKB/Swiss-Prot Summary for ARHGAP11B Gene
Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex (PubMed:25721503). Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis (PubMed:25721503). Does not possess GTPase activator activity (PubMed:25721503).