Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the ARGFX homeobox gene family. [provided by RefSeq, Jul 2008] See more...

Aliases for ARGFXP2 Gene

Aliases for ARGFXP2 Gene

  • Arginine-Fifty Homeobox Pseudogene 2 2 3 5
  • Arginine-Fifty Homeobox Pseudogene 1 3

External Ids for ARGFXP2 Gene

Previous GeneCards Identifiers for ARGFXP2 Gene

  • GC17U900558
  • GC17M027501
  • GC17M030477

Summaries for ARGFXP2 Gene

Entrez Gene Summary for ARGFXP2 Gene

  • Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the ARGFX homeobox gene family. [provided by RefSeq, Jul 2008]

GeneCards Summary for ARGFXP2 Gene

ARGFXP2 (Arginine-Fifty Homeobox Pseudogene 2) is a Pseudogene.

Additional gene information for ARGFXP2 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ARGFXP2 Gene

Genomics for ARGFXP2 Gene

GeneHancer (GH) Regulatory Elements for ARGFXP2 Gene

Promoters and enhancers for ARGFXP2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J032151 Enhancer 0.6 ENCODE 750.6 -0.9 -874 1.8 FOXA1 SP1 RXRA FOXA2 JUND YY1 ZBTB33 RAD21 HNF4A HNF4G ARGFXP2 lnc-C17orf75-11 piR-43105-274 EVI2A RHOT1 piR-35955
GH17J032144 Enhancer 0.5 ENCODE 0.4 +7.0 6996 0.2 ZNF121 BCOR CEBPB ZNF335 HDGF ZMYM3 ENSG00000214708 LOC105371730 RHOT1 ARGFXP2 lnc-C17orf75-11
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ARGFXP2 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ARGFXP2 gene promoter:
  • AhR
  • Arnt
  • Evi-1
  • HTF
  • Ik-2
  • POU2F1
  • POU2F1a
  • SRF
  • SRF (504 AA)
  • STAT1beta

Genomic Locations for ARGFXP2 Gene

Genomic Locations for ARGFXP2 Gene
chr17:32,150,357-32,151,571
(GRCh38/hg38)
Size:
1,215 bases
Orientation:
Minus strand
chr17:30,477,376-30,478,590
(GRCh37/hg19)
Size:
1,215 bases
Orientation:
Minus strand

Genomic View for ARGFXP2 Gene

Genes around ARGFXP2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARGFXP2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARGFXP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARGFXP2 Gene

Proteins for ARGFXP2 Gene

Post-translational modifications for ARGFXP2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ARGFXP2 Gene

Domains & Families for ARGFXP2 Gene

Gene Families for ARGFXP2 Gene

genes like me logo Genes that share domains with ARGFXP2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ARGFXP2 Gene

Function for ARGFXP2 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ARGFXP2 Gene

Localization for ARGFXP2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ARGFXP2 Gene

Pathways & Interactions for ARGFXP2 Gene

PathCards logo

SuperPathways for ARGFXP2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ARGFXP2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ARGFXP2 Gene

Drugs & Compounds for ARGFXP2 Gene

No Compound Related Data Available

Transcripts for ARGFXP2 Gene

mRNA/cDNA for ARGFXP2 Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for ARGFXP2 Gene

No ASD Table

Relevant External Links for ARGFXP2 Gene

GeneLoc Exon Structure for
ARGFXP2
ECgene alternative splicing isoforms for
ARGFXP2

Expression for ARGFXP2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ARGFXP2 Gene

NURSA nuclear receptor signaling pathways regulating expression of ARGFXP2 Gene:

ARGFXP2

SOURCE GeneReport for Unigene cluster for ARGFXP2 Gene:

Hs.631752
genes like me logo Genes that share expression patterns with ARGFXP2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ARGFXP2 Gene

Orthologs for ARGFXP2 Gene

Evolution for ARGFXP2 Gene

ENSEMBL:
Gene Tree for ARGFXP2 (if available)
TreeFam:
Gene Tree for ARGFXP2 (if available)

No data available for Orthologs for ARGFXP2 Gene

Paralogs for ARGFXP2 Gene

No data available for Paralogs for ARGFXP2 Gene

Variants for ARGFXP2 Gene

Sequence variations from dbSNP and Humsavar for ARGFXP2 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000831690 -- 32,151,991(-) A/C/G upstream_transcript_variant
rs1000883909 -- 32,151,710(-) A/G upstream_transcript_variant
rs1001206600 -- 32,152,389(-) A/G upstream_transcript_variant
rs1001829489 -- 32,152,838(-) C/T upstream_transcript_variant
rs1002658717 -- 32,152,399(-) A/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ARGFXP2 Gene

Variant ID Type Subtype PubMed ID
esv2669243 CNV deletion 23128226
esv2758684 CNV gain 17122850
esv3640377 CNV gain 21293372
esv3640378 CNV loss 21293372
nsv1057055 CNV gain 25217958
nsv1066680 CNV gain 25217958
nsv978412 CNV duplication 23825009

Additional Variant Information for ARGFXP2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ARGFXP2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ARGFXP2 Gene

Disorders for ARGFXP2 Gene

Additional Disease Information for ARGFXP2

No disorders were found for ARGFXP2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARGFXP2 Gene

Publications for ARGFXP2 Gene

  1. Annotation, nomenclature and evolution of four novel homeobox genes expressed in the human germ line. (PMID: 17005330) Booth HA … Holland PW (Gene 2007) 3 56

Products for ARGFXP2 Gene

Sources for ARGFXP2 Gene