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Aliases for ARFGAP2 Gene
Aliases for ARFGAP2 Gene
External Ids for ARFGAP2 Gene
- HGNC: 13504
- Entrez Gene: 84364
- Ensembl: ENSG00000149182
- OMIM: 606908
- UniProtKB: Q8N6H7
Previous HGNC Symbols for ARFGAP2 Gene
- ZNF289
Previous GeneCards Identifiers for ARFGAP2 Gene
- GC11M047143
- GC11M046884
- GC11M047185
- GC11M047280
- GC11M047937
- GC11M055803
- GC11M056025
- GC11M056167
- GC11M059684
- GC11M050790
- GC11M051585
- GC11M052247
- GC11M052907
- GC11M053575
- GC11M054241
- GC11M054907
- GC11M055606
Summaries for ARFGAP2 Gene
GeneCards Summary for ARFGAP2 Gene
ARFGAP2 (ADP Ribosylation Factor GTPase Activating Protein 2) is a Protein Coding gene. Diseases associated with ARFGAP2 include Autoimmune Lymphoproliferative Syndrome. Among its related pathways are Transport to the Golgi and subsequent modification and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is ARFGAP3.
UniProtKB/Swiss-Prot Summary for ARFGAP2 Gene
-
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.
Additional gene information for ARFGAP2 Gene
- HGNC(13504)
- Entrez Gene(84364)
- Ensembl(ENSG00000149182)
- OMIM(606908)
- UniProtKB(Q8N6H7)
- Open Targets Platform(ENSG00000149182)
- Search for ARFGAP2 at DataMed
- Search for ARFGAP2 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ARFGAP2 Gene
Genomics for ARFGAP2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ARFGAP2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ARFGAP2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ARFGAP2
- Top Transcription factor binding sites by QIAGEN in the ARFGAP2 gene promoter:
-
- AhR
- AREB6
- Arnt
- GR
- GR-alpha
- GR-beta
- NF-1
- NF-1/L
- RP58
- STAT1beta
Genomic Locations for ARFGAP2 Gene
Genomic Locations for ARFGAP2 Gene
- chr11:47,164,298-47,177,125
- (GRCh38/hg38)
- Size:
- 12,828 bases
- Orientation:
- Minus strand
- chr11:47,185,848-47,198,676
- (GRCh37/hg19)
- Size:
- 12,829 bases
- Orientation:
- Minus strand
Genomic View for ARFGAP2 Gene
Genes around ARFGAP2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11p11.2 by HGNC
- 11p11.2 by Entrez Gene
- 11p11.2 by Ensembl
ARFGAP2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ARFGAP2 Gene
Proteins for ARFGAP2 Gene
-
Protein details for ARFGAP2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N6H7-ARFG2_HUMAN
- Recommended name:
- ADP-ribosylation factor GTPase-activating protein 2
- Protein Accession:
- Q8N6H7
- B4DX29
- B7Z9M7
- D3DQQ9
- Q3LIF2
- Q8N3I1
- Q96SX7
Protein attributes for ARFGAP2 Gene
- Size:
- 521 amino acids
- Molecular mass:
- 56720 Da
- Quaternary structure:
-
- Interacts with the coatomer complex. Interacts with the C-terminal appendage domain of COPG1.
- Miscellaneous:
-
- Vero cells overexpressing truncated ARFGAP2 show accumulation of cholera toxin A subunit in the Golgi complex rather than the endoplasmic reticulum.
Protein Expression for ARFGAP2 Gene
Post-translational modifications for ARFGAP2 Gene
Other Protein References for ARFGAP2 Gene
- ENSEMBL proteins:
-
- ENSP00000434442
- ENSP00000433210
- ENSP00000434022
- ENSP00000437305
- ENSP00000434433
- ENSP00000437194
- ENSP00000432978
- ENSP00000434487
- ENSP00000431939
- ENSP00000434809
- ENSP00000431684
- ENSP00000437070
- ENSP00000431238
- ENSP00000435488
- ENSP00000431847
- ENSP00000433108
- ENSP00000400226
- ENSP00000486339
- ENSP00000486229
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ARFGAP2
- Invitrogen Antibodies for ARFGAP2 (AFLGC-Arfgap2)
-
Biorbyt antibodies for ARFGAP2
-
Custom Antibody ServicesProSci Antibodies for ARFGAP2
-
Santa Cruz Biotechnology (SCBT) Antibodies for ARFGAP2
Protein Products
-
OriGene Purified Proteins for ARFGAP2
- Search Origene for MassSpec and Protein Over-expression Lysates for ARFGAP2
- Origene Custom Protein Services for ARFGAP2
- antibodies-online: Show 4 available arfgap2 Proteins ranked by validation data
- Compare Top arfgap2 Proteins
-
Quality Products:
Assay Products
No data available for DME Specific Peptides for ARFGAP2 Gene
Domains & Families for ARFGAP2 Gene
Gene Families for ARFGAP2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for ARFGAP2 Gene
- InterPro:
- Blocks:
-
- HIV Rev interacting protein signature
- ProtoNet:
Suggested Antigen Peptide Sequences for ARFGAP2 Gene
- GenScript: Design optimal peptide antigens:
-
- Zinc finger protein 289 (ARFG2_HUMAN)
- cDNA FLJ53674, highly similar to Homo sapiens zinc finger protein 289, ID1 regulated (ZNF289), mRNA (B4DX29_HUMAN)
- cDNA FLJ58830, highly similar to Homo sapiens zinc finger protein 289, ID1 regulated (ZNF289), mRNA (B4E327_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ARFGAP2 Gene
Function for ARFGAP2 Gene
Molecular function for ARFGAP2 Gene
- UniProtKB/Swiss-Prot Function:
- GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.
Phenotypes From GWAS Catalog for ARFGAP2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IEA,IBA | 21873635 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for ARFGAP2 Gene
- GenomeRNAi human phenotypes for ARFGAP2:
-
- no effect
- Decreased viability
- Decreased epidermal growth factor (EGF) endocytosis, decreased transferrin (TF) endocytosis
- Increased viability
- Strongly decreased NFAT1-GFP nuclear translocation
- Decreased homologous recombination repair frequency
- Increased cell number in G2M, increased number of polyploid cells
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ARFGAP2 - Select products 50% OFF >
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-
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-
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miRNA for ARFGAP2 Gene
- miRTarBase miRNAs that target ARFGAP2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ARFGAP2
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Clone Products
- Applied Biological Materials (abm): Clones for ARFGAP2 - Select products 50% OFF >
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- Sino Biological Human cDNA Clone for ARFGAP2
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Cell Line Products
-
Horizon Cell Lines for ARFGAP2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ARFGAP2 Gene
Localization for ARFGAP2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ARFGAP2 Gene
- Cytoplasm. Golgi apparatus membrane. Peripheral membrane protein. Cytoplasmic side. Note=Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| golgi apparatus | 5 |
| plasma membrane | 4 |
| nucleus | 4 |
| extracellular | 1 |
| cytoskeleton | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
- Golgi apparatus (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005794 | Golgi apparatus | IDA | -- |
| GO:0005829 | cytosol | IDA,TAS | -- |
| GO:0005886 | plasma membrane | IDA | -- |
Pathways & Interactions for ARFGAP2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Transport to the Golgi and subsequent modification | ||
| 2 | Golgi-to-ER retrograde transport | ||
| 3 | Vesicle-mediated transport | ||
| 4 | Metabolism of proteins | ||
| 5 | Endocytosis | ||
Pathways by source for ARFGAP2 Gene
1 KEGG pathway for ARFGAP2 Gene
Interacting Proteins for ARFGAP2 Gene
GPS-Prot Interaction Network for ARFGAP2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006888 | ER to Golgi vesicle-mediated transport | TAS | -- |
| GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER | TAS | -- |
| GO:0015031 | protein transport | IEA | -- |
| GO:0016192 | vesicle-mediated transport | IEA | -- |
| GO:0043547 | positive regulation of GTPase activity | IEA | -- |
No data available for SIGNOR curated interactions for ARFGAP2 Gene
Drugs & Compounds for ARFGAP2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Guanosine triphosphate | Experimental | Pharma | 0 |
Transcripts for ARFGAP2 Gene
mRNA/cDNA for ARFGAP2 Gene
- 2 REFSEQ mRNAs :
- 13 NCBI additional mRNA sequence :
- 30 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000524782 2773 nts (view in UCSC)
- ENST00000395449 1772 nts (view in UCSC)
- ENST00000533243 1558 nts (view in UCSC)
- ENST00000527776 709 nts (view in UCSC)
- ENST00000526342 474 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ARFGAP2 - Select products 50% OFF >
- * ARFGAP2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ARFGAP2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ARFGAP2
-
Santa Cruz Biotechnology (SCBT) CRISPR for ARFGAP2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ARFGAP2
- Browse OriGene Inhibitory RNA Products For ARFGAP2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ARFGAP2
Clone Products
- Applied Biological Materials (abm): Clones for ARFGAP2 - Select products 50% OFF >
- * ARFGAP2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ARFGAP2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ARFGAP2
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||
| SP7: |
Relevant External Links for ARFGAP2 Gene
- GeneLoc Exon Structure for
- ARFGAP2
Expression for ARFGAP2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Peripheral blood mononuclear cells (17.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ARFGAP2 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ARFGAP2
SOURCE GeneReport for Unigene cluster for ARFGAP2 Gene:
Hs.436204Evidence on tissue expression from TISSUES for ARFGAP2 Gene
- Nervous system(5)
- Eye(4.5)
- Liver(4.4)
- Lung(3.4)
- Intestine(3.2)
- Kidney(2.9)
- Skin(2.9)
- Pancreas(2)
Primer Products
-
OriGene qPCR primer pairs for ARFGAP2
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ARFGAP2 Gene
Orthologs for ARFGAP2 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ARFGAP2 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | ARFGAP2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | ARFGAP2 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Arfgap2 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | ARFGAP2 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Arfgap2 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | ARFGAP2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | ARFGAP2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| -- 31 |
|
OneToMany | |||
| -- 31 |
|
OneToMany | |||
| -- 31 |
|
OneToMany | |||
| -- 31 |
|
OneToMany | |||
| -- 31 |
|
OneToMany | |||
| -- 31 |
|
OneToMany | |||
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | arfgap2 30 |
|
||
| Str.6000 30 |
|
||||
| Zebrafish (Danio rerio) |
Actinopterygii | arfgap2 30 31 |
|
OneToOne | |
| wufa11e07 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | ArfGAP3 30 31 |
|
OneToMany | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP005609 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | F07F6.4 30 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | GLO3 31 |
|
OneToMany | |
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | RPA 30 |
|
||
| Barley (Hordeum vulgare) |
Liliopsida | Hv.5106 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
ManyToMany | |
| -- 31 |
|
ManyToMany |
- Species where no ortholog for ARFGAP2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for ARFGAP2 Gene
- ENSEMBL:
- Gene Tree for ARFGAP2 (if available)
- TreeFam:
- Gene Tree for ARFGAP2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ARFGAP2: view image
Paralogs for ARFGAP2 Gene
Paralogs for ARFGAP2 Gene
(8) SIMAP similar genes for ARFGAP2 Gene using alignment to 19 proteins:
- ARFG2_HUMAN
- B4DX29_HUMAN
- B7Z9M7_HUMAN
- E9PIY6_HUMAN
- E9PJT7_HUMAN
- E9PK28_HUMAN
- E9PM18_HUMAN
- E9PM63_HUMAN
- E9PMR9_HUMAN
- E9PMU9_HUMAN
- E9PN48_HUMAN
- E9PNY8_HUMAN
- E9PQP3_HUMAN
- G5E9L0_HUMAN
- H0YCA3_HUMAN
- H0YCL1_HUMAN
- H0YDN9_HUMAN
- H0YDX1_HUMAN
- H0YF45_HUMAN
Variants for ARFGAP2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ARFGAP2 Gene
| SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs11542793 | - | p.Pro143Arg | |||
| rs34662994 | - | p.Arg339His | |||
| rs35950498 | - | p.Arg406Trp | |||
| rs3740691 | - | p.Ser411Asn |
Residual Variation Intolerance Score:
59.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
11.35;
92.68% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ARFGAP2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ARFGAP2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ARFGAP2 Gene
Disorders for ARFGAP2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| autoimmune lymphoproliferative syndrome |
|
|
Search ARFGAP2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ARFGAP2
No data available for UniProtKB/Swiss-Prot and Genatlas for ARFGAP2 Gene
Publications for ARFGAP2 Gene
- Gamma-COP appendage domain - structure and function. (PMID: 14690497) Watson PJ … Owen DJ (Traffic (Copenhagen, Denmark) 2004) 2 3 4
- Two human ARFGAPs associated with COP-I-coated vesicles. (PMID: 17760859) Frigerio G … Duden R (Traffic (Copenhagen, Denmark) 2007) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma. (PMID: 12880961) Ohira M … Nakagawara A (Cancer letters 2003) 3 4
ExternalLinks
Products for ARFGAP2 Gene
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- OriGene qPCR primer pairs for ARFGAP2
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- Sino Biological Human cDNA Clone for ARFGAP2
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- High-throughput Antibody Production Service
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- Novus Biologicals proteins and lysates for ARFGAP2
- Browse Antibodies
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- Invitrogen Antibodies for ARFGAP2 (AFLGC-Arfgap2)
- VectorBuilder Custom and pre-made DNA vectors for ARFGAP2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for ARFGAP2 (ie. lentivirus, AAV, adenovirus)
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- antibodies-online: Show 27 available arfgap2 Antibodies ranked by validation data
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- Quality Products:
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- Biorbyt antibodies for ARFGAP2
Sources for ARFGAP2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB