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Aliases for AQP7P3 Gene

Aliases for AQP7P3 Gene

  • Aquaporin 7 Pseudogene 3 2 3 5
  • Aquaporin Pseudogene AQPap-3 3
  • AQPap-3 3

External Ids for AQP7P3 Gene

Previous GeneCards Identifiers for AQP7P3 Gene

  • GC09M045777
  • GC09P042847
  • GC09P042858

Summaries for AQP7P3 Gene

GeneCards Summary for AQP7P3 Gene

AQP7P3 (Aquaporin 7 Pseudogene 3) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include transporter activity.

Additional gene information for AQP7P3 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AQP7P3 Gene

Genomics for AQP7P3 Gene

GeneHancer (GH) Regulatory Elements for AQP7P3 Gene

Promoters and enhancers for AQP7P3 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J065872 Enhancer 0.2 Ensembl 0.7 -3.7 -3673 2.6 LOC101928195 AQP7P3 BMS1P13
GH09J065868 Enhancer 0.2 Ensembl 0.4 -8.5 -8473 1.4 AQP7P3 LOC101928195 BMS1P13
GH09J065864 Enhancer 0.2 Ensembl 0.4 -12.4 -12373 2 AQP7P3 LOC101928195 BMS1P13
GH09J065888 Enhancer 0.2 Ensembl 0.4 +11.1 11126 0.6 AQP7P3 LOC101928195 ENSG00000273668
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around AQP7P3 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the AQP7P3 gene promoter:
  • RORalpha1
  • RSRFC4
  • Oct-B1
  • oct-B2
  • oct-B3
  • POU2F1
  • POU2F1a
  • POU2F2C
  • POU2F2B
  • POU2F2 (Oct-2.1)

Genomic Locations for AQP7P3 Gene

Genomic Locations for AQP7P3 Gene
chr9:65,877,574-65,912,560
(GRCh38/hg38)
Size:
34,987 bases
Orientation:
Plus strand
chr9:42,858,072-42,893,138
(GRCh37/hg19)
Size:
35,067 bases
Orientation:
Plus strand

Genomic View for AQP7P3 Gene

Genes around AQP7P3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AQP7P3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AQP7P3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AQP7P3 Gene

Proteins for AQP7P3 Gene

  • Protein details for AQP7P3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NL99-AQP73_HUMAN
    Recommended name:
    Putative aquaporin-7-like protein 3
    Protein Accession:
    A6NL99

    Protein attributes for AQP7P3 Gene

    Size:
    342 amino acids
    Molecular mass:
    37357 Da
    Quaternary structure:
    No Data Available

neXtProt entry for AQP7P3 Gene

Post-translational modifications for AQP7P3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for AQP7P3 Gene

Domains & Families for AQP7P3 Gene

Protein Domains for AQP7P3 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for AQP7P3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NL99

UniProtKB/Swiss-Prot:

AQP73_HUMAN :
  • Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro/Ala-Ala/Ser (NPA).
  • Belongs to the MIP/aquaporin (TC 1.A.8) family.
Domain:
  • Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro/Ala-Ala/Ser (NPA).
Family:
  • Belongs to the MIP/aquaporin (TC 1.A.8) family.
genes like me logo Genes that share domains with AQP7P3: view

No data available for Gene Families for AQP7P3 Gene

Function for AQP7P3 Gene

Gene Ontology (GO) - Molecular Function for AQP7P3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015204 urea transmembrane transporter activity IBA --
GO:0015267 channel activity IEA --
genes like me logo Genes that share ontologies with AQP7P3: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for AQP7P3 Gene

Localization for AQP7P3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for AQP7P3 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for AQP7P3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with AQP7P3: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for AQP7P3 Gene

Pathways & Interactions for AQP7P3 Gene

SuperPathways for AQP7P3 Gene

No Data Available

Interacting Proteins for AQP7P3 Gene

Gene Ontology (GO) - Biological Process for AQP7P3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with AQP7P3: view

No data available for Pathways by source and SIGNOR curated interactions for AQP7P3 Gene

Drugs & Compounds for AQP7P3 Gene

No Compound Related Data Available

Transcripts for AQP7P3 Gene

mRNA/cDNA for AQP7P3 Gene

(2) Additional mRNA sequences :
(32) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for AQP7P3 Gene

Aquaporin 7 pseudogene 3:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for AQP7P3 Gene

No ASD Table

Relevant External Links for AQP7P3 Gene

GeneLoc Exon Structure for
AQP7P3
ECgene alternative splicing isoforms for
AQP7P3

Expression for AQP7P3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for AQP7P3 Gene

mRNA differential expression in normal tissues according to GTEx for AQP7P3 Gene

This gene is overexpressed in Adipose - Visceral (Omentum) (x11.8), Adipose - Subcutaneous (x8.7), and Breast - Mammary Tissue (x6.2).

NURSA nuclear receptor signaling pathways regulating expression of AQP7P3 Gene:

AQP7P3

SOURCE GeneReport for Unigene cluster for AQP7P3 Gene:

Hs.743215
genes like me logo Genes that share expression patterns with AQP7P3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AQP7P3 Gene

Orthologs for AQP7P3 Gene

Evolution for AQP7P3 Gene

ENSEMBL:
Gene Tree for AQP7P3 (if available)
TreeFam:
Gene Tree for AQP7P3 (if available)

No data available for Orthologs for AQP7P3 Gene

Paralogs for AQP7P3 Gene

(5) SIMAP similar genes for AQP7P3 Gene using alignment to 1 proteins:

  • AQP73_HUMAN
genes like me logo Genes that share paralogs with AQP7P3: view

No data available for Paralogs for AQP7P3 Gene

Variants for AQP7P3 Gene

Sequence variations from dbSNP and Humsavar for AQP7P3 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000110569 -- 65,897,874(+) C/T intron_variant
rs1000546136 -- 65,897,408(+) A/C intron_variant
rs1001004273 -- 65,895,792(+) C/G intron_variant
rs1001150872 -- 65,891,643(+) A/G intron_variant
rs1001514017 -- 65,893,391(+) A/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for AQP7P3 Gene

Variant ID Type Subtype PubMed ID
nsv982283 CNV duplication 23825009
nsv982282 CNV duplication 23825009
nsv972703 CNV duplication 23825009
nsv972381 CNV duplication 23825009
nsv968682 CNV duplication 23825009
nsv951196 CNV duplication 24416366
nsv8497 CNV gain+loss 18304495
nsv8488 CNV loss 18304495
nsv1153561 CNV duplication 26484159
nsv1141609 CNV duplication 24896259
nsv1139979 CNV duplication 24896259
nsv1119298 CNV duplication 24896259
nsv1115822 CNV duplication 24896259
nsv1077545 CNV duplication 25765185
nsv1077544 CNV duplication 25765185
esv3450991 CNV duplication 20981092
esv3432950 CNV duplication 20981092
esv3411153 CNV duplication 20981092
esv3392083 CNV duplication 20981092
esv3391973 CNV duplication 20981092
esv3387875 CNV duplication 20981092
esv3350808 CNV duplication 20981092
esv3330487 CNV duplication 20981092
esv3329673 CNV duplication 20981092
esv3328216 CNV duplication 20981092
dgv94n68 CNV loss 17160897
dgv93n68 CNV loss 17160897
dgv4399e59 CNV duplication 20981092
dgv4398e59 CNV duplication 20981092
dgv4397e59 CNV duplication 20981092

Additional Variant Information for AQP7P3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
AQP7P3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for AQP7P3 Gene

Disorders for AQP7P3 Gene

Additional Disease Information for AQP7P3

No disorders were found for AQP7P3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AQP7P3 Gene

Publications for AQP7P3 Gene

  1. Human aquaporin adipose (AQPap) gene. Genomic structure, promoter analysis and functional mutation. (PMID: 11952783) Kondo H … Matsuzawa Y (European journal of biochemistry 2002) 2 3 58
  2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M … Moll S (Journal of proteomics 2013) 3 58
  3. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for AQP7P3 Gene

Sources for AQP7P3 Gene

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