Aliases for AQP6 Gene
External Ids for AQP6 Gene
Previous HGNC Symbols for AQP6 Gene
Previous GeneCards Identifiers for AQP6 Gene
The protein encoded by this gene is an aquaporin protein, which functions as a water channel in cells. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This protein is specific for the kidney. This gene and related family members AQP0, AQP2, and AQP5 reside in a cluster on chromosome 12q13. [provided by RefSeq, Jul 2008]
GeneCards Summary for AQP6 Gene
AQP6 (Aquaporin 6) is a Protein Coding gene. Diseases associated with AQP6 include Acoustic Neuroma and Inner Ear Disease. Among its related pathways are Aquaporin-mediated transport and Nanog in Mammalian ESC Pluripotency. Gene Ontology (GO) annotations related to this gene include transporter activity and glycerol channel activity. An important paralog of this gene is AQP2.
UniProtKB/Swiss-Prot Summary for AQP6 Gene
Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism.
Aquaporins (AQPs) are integral membrane proteins that facilitate the transport of water across biological membranes along an osmotic gradient. There have been 13 AQP isoforms (AQP0-AQP12) identified in humans and rodents to date.