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Aliases for APTR Gene

Subcategory (RNA class) for APTR Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for APTR Gene

  • Alu-Mediated CDKN1A/P21 Transcriptional Regulator (Non-Protein Coding) 2 3 5
  • RSBN1L Antisense RNA 1 (Non-Protein Coding) 2 3
  • RSBN1L-AS1 3

External Ids for APTR Gene

Previous HGNC Symbols for APTR Gene

  • RSBN1L-AS1

Summaries for APTR Gene

GeneCards Summary for APTR Gene

APTR (Alu-Mediated CDKN1A/P21 Transcriptional Regulator (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for APTR Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for APTR Gene

Genomics for APTR Gene

GeneHancer (GH) Regulatory Elements for APTR Gene

Promoters and enhancers for APTR Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I077694 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 588.2 +0.3 256 5.4 HDGF PKNOX1 SMAD1 FOXA2 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 APTR RSBN1L SPDYE18 TMEM60 SPDYE17 PHTF2 FAM185BP PMS2P9 DTX2P1 PTPN12
GH07I077796 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE 25.2 -101.6 -101581 4.5 HDGF FOXA2 PKNOX1 CLOCK ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B TMEM60 PHTF2 RSBN1L SPDYE18 FAM185BP SPDYE17 APTR PMS2P9 LOC100422695 CCDC146
GH07I077535 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 23.8 +158.8 158843 5.4 HDGF HNRNPUL1 PKNOX1 CLOCK FOXA2 SMAD1 MLX ARNT ZFP64 ARID4B PTPN12 GC07M077535 RSBN1L FAM185BP PMS2P9 APTR DTX2P1 POMZP3 CCDC146 LOC105375363
GH07I077720 Enhancer 0.9 Ensembl ENCODE 51.5 -23.4 -23382 0.7 USF1 ZNF362 ZNF189 OSR2 ZSCAN21 ZNF335 ZFHX2 GLIS1 ZNF629 PRDM10 APTR RSBN1L PHTF2 TMEM60 PTPN12
GH07I077684 Enhancer 0.9 Ensembl ENCODE 41 +12.4 12388 1.9 CTCF MXI1 USF1 ZNF449 INSM2 MAX SIN3A YY1 GATA3 ZBTB48 APTR PTPN12 PHTF2 TMEM60 RSBN1L GC07P077654
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around APTR on UCSC Golden Path with GeneCards custom track

Genomic Locations for APTR Gene

Genomic Locations for APTR Gene
chr7:77,657,660-77,697,345
(GRCh38/hg38)
Size:
39,686 bases
Orientation:
Minus strand
chr7:77,286,977-77,326,662
(GRCh37/hg19)

Genomic View for APTR Gene

Genes around APTR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
APTR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for APTR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for APTR Gene

Proteins for APTR Gene

Post-translational modifications for APTR Gene

No Post-translational modifications

No data available for DME Specific Peptides for APTR Gene

Domains & Families for APTR Gene

Gene Families for APTR Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with APTR: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for APTR Gene

Function for APTR Gene

Phenotypes From GWAS Catalog for APTR Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for APTR Gene

Localization for APTR Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for APTR Gene

Pathways & Interactions for APTR Gene

No Data Available

Interacting Proteins for APTR Gene

Gene Ontology (GO) - Biological Process for APTR Gene

None

No data available for Pathways by source and SIGNOR curated interactions for APTR Gene

Drugs & Compounds for APTR Gene

No Compound Related Data Available

Transcripts for APTR Gene

mRNA/cDNA for APTR Gene

(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for APTR Gene

No ASD Table

Relevant External Links for APTR Gene

GeneLoc Exon Structure for
APTR
ECgene alternative splicing isoforms for
APTR

Expression for APTR Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for APTR Gene

NURSA nuclear receptor signaling pathways regulating expression of APTR Gene:

APTR
genes like me logo Genes that share expression patterns with APTR: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for APTR Gene

Orthologs for APTR Gene

Evolution for APTR Gene

ENSEMBL:
Gene Tree for APTR (if available)
TreeFam:
Gene Tree for APTR (if available)

No data available for Orthologs for APTR Gene

Paralogs for APTR Gene

No data available for Paralogs for APTR Gene

Variants for APTR Gene

Sequence variations from dbSNP and Humsavar for APTR Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000181461 -- 77,672,179(-) G/A genic_downstream_transcript_variant, intron_variant
rs1000339579 -- 77,675,818(-) C/G genic_downstream_transcript_variant, intron_variant
rs1000350679 -- 77,686,586(-) C/A intron_variant
rs1000405551 -- 77,688,260(-) G/C intron_variant
rs1000487980 -- 77,686,395(-) A/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for APTR Gene

Variant ID Type Subtype PubMed ID
esv2657737 CNV deletion 23128226
esv2661869 CNV deletion 23128226
esv2675970 CNV deletion 23128226
esv2734703 CNV deletion 23290073
esv3613804 CNV loss 21293372
esv3613805 CNV loss 21293372
esv3613806 CNV loss 21293372
nsv1114979 CNV deletion 24896259
nsv831039 CNV gain 17160897

Additional Variant Information for APTR Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
APTR

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for APTR Gene

Disorders for APTR Gene

Additional Disease Information for APTR

No disorders were found for APTR Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for APTR Gene

Publications for APTR Gene

  1. A new lncRNA, APTR, associates with and represses the CDKN1A/p21 promoter by recruiting polycomb proteins. (PMID: 24748121) Negishi M … Dutta A (PloS one 2014) 2 3 58
  2. APTR is a prognostic marker in cirrhotic patients with portal hypertension during TIPS procedure. (PMID: 29274906) Yu S … Zhou Q (Gene 2018) 3

Products for APTR Gene

Sources for APTR Gene

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