Aliases for APTR Gene

Subcategory (RNA class) for APTR Gene

lncRNA

Number of RNA Genes sources:

3 / 17

Aliases for APTR Gene

  • Alu-Mediated CDKN1A/P21 Transcriptional Regulator 2 3 5
  • APTR 2 5 165
  • Alu-Mediated CDKN1A/P21 Transcriptional Regulator (Non-Protein Coding) 2 3
  • RSBN1L Antisense RNA 1 (Non-Protein Coding) 2 3
  • NONHSAG048057.2 91
  • HSALNG0059132 164
  • RSBN1L-AS1 3

External Ids for APTR Gene

Previous HGNC Symbols for APTR Gene

  • RSBN1L-AS1

Previous GeneCards Identifiers for APTR Gene

  • GC07M077657

Summaries for APTR Gene

GeneCards Summary for APTR Gene

APTR (Alu-Mediated CDKN1A/P21 Transcriptional Regulator) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with APTR include Liver Cirrhosis and Glioma Susceptibility 1.

Rfam classification for APTR Gene

  • Metazoan signal recognition particle RNA

Additional gene information for APTR Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for APTR Gene

Genomics for APTR Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for APTR Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around APTR on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for APTR Gene

Genomic Locations for APTR Gene
chr7:77,477,984-77,697,345
(GRCh38/hg38)
Size:
219,362 bases
Orientation:
Minus strand
chr7:77,286,977-77,326,662
(GRCh37/hg19)
Size:
39,686 bases
Orientation:
Minus strand

Genomic View for APTR Gene

Genes around APTR on UCSC Golden Path with GeneCards custom track
APTR in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
APTR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for APTR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for APTR Gene

Proteins for APTR Gene

No data available for DME Specific Peptides for APTR Gene

Domains & Families for APTR Gene

Gene Families for APTR Gene

genes like me logo Genes that share domains with APTR: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for APTR Gene

Function for APTR Gene

Phenotypes From GWAS Catalog for APTR Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for APTR Gene

Localization for APTR Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for APTR gene
Compartment Confidence
extracellular 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for APTR Gene

Pathways & Interactions for APTR Gene

PathCards logo

SuperPathways for APTR Gene

No Data Available

Gene Ontology (GO) - Biological Process for APTR Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for APTR Gene

Drugs & Compounds for APTR Gene

No Compound Related Data Available

Transcripts for APTR Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for APTR Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000034963E_9606 lncRNA 2029 4

RefSeq: NR_134254,

Ensembl: ENST00000440088 (view in UCSC) ,

LNCipedia: APTR:9,

NONCODE: NONHSAT121668.2,

URS000075BCAA_9606 lncRNA 1978 3

HGNC: 44173,

RefSeq: NR_038361,

LNCipedia: APTR:1,

URS00004B5474_9606 lncRNA 902 3

Ensembl: ENST00000447009 (view in UCSC) ,

LNCipedia: APTR:11,

NONCODE: NONHSAT213643.1,

URS00002715A5_9606 lncRNA 609 3

Ensembl: ENST00000416650 (view in UCSC) ,

LNCipedia: APTR:10,

NONCODE: NONHSAT121675.2,

URS0000A76BE6_9606 lncRNA 2156 2

RefSeq: NR_134253,

LNCipedia: APTR:28,

APTR in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for APTR Gene

3 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for APTR Gene

No ASD Table

Relevant External Links for APTR Gene

GeneLoc Exon Structure for
APTR

Expression for APTR Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for APTR Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for APTR

genes like me logo Genes that share expression patterns with APTR: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for APTR Gene

Orthologs for APTR Gene

Evolution for APTR Gene

ENSEMBL:
Gene Tree for APTR (if available)
TreeFam:
Gene Tree for APTR (if available)

No data available for Orthologs for APTR Gene

Paralogs for APTR Gene

No data available for Paralogs for APTR Gene

Variants for APTR Gene

Additional dbSNP identifiers (rs#s) for APTR Gene

Structural Variations from Database of Genomic Variants (DGV) for APTR Gene

Variant ID Type Subtype PubMed ID
esv2657737 CNV deletion 23128226
esv2661869 CNV deletion 23128226
esv2675970 CNV deletion 23128226
esv2734703 CNV deletion 23290073
esv3613804 CNV loss 21293372
esv3613805 CNV loss 21293372
esv3613806 CNV loss 21293372
nsv1114979 CNV deletion 24896259
nsv831039 CNV gain 17160897

Additional Variant Information for APTR Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
APTR

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for APTR Gene

Disorders for APTR Gene

MalaCards: The human disease database

(3) MalaCards diseases for APTR Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
liver cirrhosis
  • cirrhosis
glioma susceptibility 1
  • glm1
high molecular weight kininogen deficiency
  • hmwk deficiency
- elite association - COSMIC cancer census association via MalaCards
Search APTR in MalaCards View complete list of genes associated with diseases

Additional Disease Information for APTR

genes like me logo Genes that share disorders with APTR: view

No data available for UniProtKB/Swiss-Prot and Genatlas for APTR Gene

Publications for APTR Gene

  1. A new lncRNA, APTR, associates with and represses the CDKN1A/p21 promoter by recruiting polycomb proteins. (PMID: 24748121) Negishi M … Dutta A (PloS one 2014) 2 3
  2. Long noncoding RNA APTR contributes to osteosarcoma progression through repression of miR-132-3p and upregulation of yes-associated protein 1. (PMID: 30317613) Guan H … Li Y (Journal of cellular physiology 2019) 3
  3. APTR is a prognostic marker in cirrhotic patients with portal hypertension during TIPS procedure. (PMID: 29274906) Yu S … Zhou Q (Gene 2018) 3

Products for APTR Gene

Sources for APTR Gene