Aliases for APPBP2 Gene
External Ids for APPBP2 Gene
Previous GeneCards Identifiers for APPBP2 Gene
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
GeneCards Summary for APPBP2 Gene
APPBP2 (Amyloid Beta Precursor Protein Binding Protein 2) is a Protein Coding gene. Among its related pathways are Regulation of Androgen receptor activity. Gene Ontology (GO) annotations related to this gene include microtubule motor activity. An important paralog of this gene is KLC2.
UniProtKB/Swiss-Prot Summary for APPBP2 Gene
May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.