Aliases for APOOL Gene
External Ids for APOOL Gene
Previous HGNC Symbols for APOOL Gene
Previous GeneCards Identifiers for APOOL Gene
This gene encodes a protein which contains an apolipoprotein O superfamily domain. This domain is found on proteins in circulating lipoprotein complexes. [provided by RefSeq, Sep 2011]
GeneCards Summary for APOOL Gene
UniProtKB/Swiss-Prot Summary for APOOL Gene
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:23704930), (PubMed:25764979).