Aliases for ANXA8 Gene
External Ids for ANXA8 Gene
Previous HGNC Symbols for ANXA8 Gene
Previous GeneCards Identifiers for ANXA8 Gene
This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. [provided by RefSeq, Jul 2008]
GeneCards Summary for ANXA8 Gene
ANXA8 (Annexin A8) is a Protein Coding gene. Diseases associated with ANXA8 include Penis Squamous Cell Carcinoma and Hypothyroidism, Congenital, Nongoitrous, 6. Gene Ontology (GO) annotations related to this gene include calcium ion binding and calcium-dependent phospholipid binding. An important paralog of this gene is ANXA8L1.
UniProtKB/Swiss-Prot Summary for ANXA8 Gene
This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.