Aliases for ANXA8 Gene
External Ids for ANXA8 Gene
Previous HGNC Symbols for ANXA8 Gene
Previous GeneCards Identifiers for ANXA8 Gene
This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. [provided by RefSeq, Jul 2008]
GeneCards Summary for ANXA8 Gene
ANXA8 (Annexin A8) is a Protein Coding gene. Diseases associated with ANXA8 include Acute Promyelocytic Leukemia. Gene Ontology (GO) annotations related to this gene include calcium ion binding and calcium-dependent phospholipid binding. An important paralog of this gene is ANXA8L1.
UniProtKB/Swiss-Prot for ANXA8 Gene
This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.