Aliases for ANXA11 Gene
External Ids for ANXA11 Gene
Previous HGNC Symbols for ANXA11 Gene
Previous GeneCards Identifiers for ANXA11 Gene
This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Several transcript variants encoding two different isoforms have been identified. [provided by RefSeq, Dec 2015]
GeneCards Summary for ANXA11 Gene
ANXA11 (Annexin A11) is a Protein Coding gene. Diseases associated with ANXA11 include Amyotrophic Lateral Sclerosis 23 and Amyotrophic Lateral Sclerosis 1. Gene Ontology (GO) annotations related to this gene include calcium-dependent protein binding. An important paralog of this gene is ANXA7.
UniProtKB/Swiss-Prot Summary for ANXA11 Gene
Binds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation and completion of the terminal phase of cytokinesis.