Aliases for ANP32E Gene
External Ids for ANP32E Gene
Previous GeneCards Identifiers for ANP32E Gene
GeneCards Summary for ANP32E Gene
ANP32E (Acidic Nuclear Phosphoprotein 32 Family Member E) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include histone binding and phosphatase inhibitor activity. An important paralog of this gene is ANP32A.
UniProtKB/Swiss-Prot Summary for ANP32E Gene
Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AFZ from the nucleosome: removes H2A.Z/H2AFZ from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AFZ in the nucleosome. May stabilize the evicted H2A.Z/H2AFZ-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state (PubMed:24463511). Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis.