Aliases for ANO7 Gene
External Ids for ANO7 Gene
Previous HGNC Symbols for ANO7 Gene
Previous GeneCards Identifiers for ANO7 Gene
This prostate-specific gene encodes a cytoplasmic protein, as well as a polytopic membrane protein which may serve as a target in prostate cancer diagnosis and immunotherapy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2011]
GeneCards Summary for ANO7 Gene
ANO7 (Anoctamin 7) is a Protein Coding gene. Diseases associated with ANO7 include Prostate Cancer and Spinocerebellar Ataxia, Autosomal Recessive 10. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Ion channel transport. Gene Ontology (GO) annotations related to this gene include intracellular calcium activated chloride channel activity and phospholipid scramblase activity. An important paralog of this gene is ANO4.
UniProtKB/Swiss-Prot Summary for ANO7 Gene
Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity (PubMed:22075693). May play a role in cell-cell interactions (PubMed:17308099).