Aliases for ANKUB1 Gene

Aliases for ANKUB1 Gene

  • Ankyrin Repeat And Ubiquitin Domain Containing 1 2 3 5
  • Protein ANKUB1 3 4
  • C3orf16 3 4
  • Ankyrin Repeat And Ubiquitin Domain-Containing 1 4
  • Chromosome 3 Open Reading Frame 16 2

External Ids for ANKUB1 Gene

Previous HGNC Symbols for ANKUB1 Gene

  • C3orf16

Previous GeneCards Identifiers for ANKUB1 Gene

  • GC03M149479

Summaries for ANKUB1 Gene

GeneCards Summary for ANKUB1 Gene

ANKUB1 (Ankyrin Repeat And Ubiquitin Domain Containing 1) is a Protein Coding gene. An important paralog of this gene is ZFAND4.

Additional gene information for ANKUB1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ANKUB1 Gene

Genomics for ANKUB1 Gene

GeneHancer (GH) Regulatory Elements for ANKUB1 Gene

Promoters and enhancers for ANKUB1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ANKUB1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ANKUB1 Gene

Genomic Locations for ANKUB1 Gene
207,738 bases
Minus strand
207,286 bases
Minus strand

Genomic View for ANKUB1 Gene

Genes around ANKUB1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKUB1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKUB1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKUB1 Gene

Proteins for ANKUB1 Gene

  • Protein details for ANKUB1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein ANKUB1
    Protein Accession:
    Secondary Accessions:
    • B4E2N8
    • E9PHT4

    Protein attributes for ANKUB1 Gene

    502 amino acids
    Molecular mass:
    56600 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ANKUB1 Gene


neXtProt entry for ANKUB1 Gene

Post-translational modifications for ANKUB1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ANKUB1 Gene

Domains & Families for ANKUB1 Gene

Gene Families for ANKUB1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ANKUB1 Gene

Suggested Antigen Peptide Sequences for ANKUB1 Gene

GenScript: Design optimal peptide antigens:
  • Ankyrin repeat and ubiquitin domain-containing 1 (ANKUB_HUMAN)
  • cDNA FLJ59820 (B4E2N8_HUMAN)
genes like me logo Genes that share domains with ANKUB1: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ANKUB1 Gene

Function for ANKUB1 Gene

Phenotypes From GWAS Catalog for ANKUB1 Gene

Phenotypes for ANKUB1 Gene

genes like me logo Genes that share phenotypes with ANKUB1: view

Animal Models for ANKUB1 Gene

MGI Knock Outs for ANKUB1:
  • Ankub1 Ankub1<tm1.1(KOMP)Vlcg>

Animal Model Products

CRISPR Products

miRNA for ANKUB1 Gene

miRTarBase miRNAs that target ANKUB1

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ANKUB1 Gene

Localization for ANKUB1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ANKUB1 gene
Compartment Confidence
peroxisome 1
nucleus 1
cytosol 1
extracellular 0
golgi apparatus 0

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ANKUB1 Gene

Pathways & Interactions for ANKUB1 Gene

PathCards logo

SuperPathways for ANKUB1 Gene

No Data Available

Interacting Proteins for ANKUB1 Gene

Selected Interacting proteins: A6NFN9-ANKUB_HUMAN for ANKUB1 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for ANKUB1 Gene


No data available for Pathways by source and SIGNOR curated interactions for ANKUB1 Gene

Drugs & Compounds for ANKUB1 Gene

No Compound Related Data Available

Transcripts for ANKUB1 Gene

mRNA/cDNA for ANKUB1 Gene

(3) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(9) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKUB1 Gene

No ASD Table

Relevant External Links for ANKUB1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKUB1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ANKUB1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ANKUB1 Gene

This gene is overexpressed in Cervix - Endocervix (x10.3), Testis (x10.0), and Lung (x4.4).

NURSA nuclear receptor signaling pathways regulating expression of ANKUB1 Gene:


SOURCE GeneReport for Unigene cluster for ANKUB1 Gene:

genes like me logo Genes that share expression patterns with ANKUB1: view

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKUB1 Gene

Orthologs for ANKUB1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKUB1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ANKUB1 33 32
  • 99.45 (n)
(Canis familiaris)
Mammalia ANKUB1 32
  • 88.77 (n)
(Bos Taurus)
Mammalia ANKUB1 33 32
  • 87.48 (n)
(Mus musculus)
Mammalia Gm410 33 32
  • 86.32 (n)
Ankub1 17
(Rattus norvegicus)
Mammalia Ankub1 32
  • 82.1 (n)
(Ornithorhynchus anatinus)
Mammalia ANKUB1 33
  • 73 (a)
(Monodelphis domestica)
Mammalia ANKUB1 33
  • 60 (a)
(Anolis carolinensis)
Reptilia ANKUB1 33
  • 57 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ankub1 32
  • 59.85 (n)
Str.19383 32
Species where no ortholog for ANKUB1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ANKUB1 Gene

Gene Tree for ANKUB1 (if available)
Gene Tree for ANKUB1 (if available)
Evolutionary constrained regions (ECRs) for ANKUB1: view image

Paralogs for ANKUB1 Gene

Paralogs for ANKUB1 Gene

genes like me logo Genes that share paralogs with ANKUB1: view

Variants for ANKUB1 Gene

Sequence variations from dbSNP and Humsavar for ANKUB1 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1000165825 -- 149,765,497(-) C/T genic_downstream_transcript_variant, intron_variant
rs1000179838 -- 149,761,212(-) C/T 3_prime_UTR_variant, downstream_transcript_variant, genic_downstream_transcript_variant
rs1000413547 -- 149,794,081(-) C/G upstream_transcript_variant
rs1000493144 -- 149,766,970(-) G/C 3_prime_UTR_variant, intron_variant
rs1000529793 -- 149,771,214(-) T/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ANKUB1 Gene

Variant ID Type Subtype PubMed ID
esv1145264 CNV insertion 17803354
esv34142 CNV loss 18971310
esv3598148 CNV loss 21293372
nsv829754 CNV gain 17160897

Variation tolerance for ANKUB1 Gene

Gene Damage Index Score: 4.99; 68.33% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ANKUB1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKUB1 Gene

Disorders for ANKUB1 Gene

Additional Disease Information for ANKUB1

No disorders were found for ANKUB1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKUB1 Gene

Publications for ANKUB1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 56
  2. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3 56
  3. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny DM … Gibbs RA (Nature 2006) 4 56
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 56
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo MF … Soares MB (Genome research 1996) 3 56

Products for ANKUB1 Gene

Sources for ANKUB1 Gene