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Aliases for ANKRD9 Gene

Aliases for ANKRD9 Gene

  • Ankyrin Repeat Domain 9 2 3 5

External Ids for ANKRD9 Gene

Previous GeneCards Identifiers for ANKRD9 Gene

  • GC14M096788
  • GC14M100964
  • GC14M100965
  • GC14M100966
  • GC14M102042
  • GC14M102973
  • GC14M083150

Summaries for ANKRD9 Gene

GeneCards Summary for ANKRD9 Gene

ANKRD9 (Ankyrin Repeat Domain 9) is a Protein Coding gene.

Additional gene information for ANKRD9 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD9 Gene

Genomics for ANKRD9 Gene

GeneHancer (GH) Regulatory Elements for ANKRD9 Gene

Promoters and enhancers for ANKRD9 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I102507 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 574 -0.1 -59 4.9 PKNOX1 ATF1 FOXA2 ZNF133 ARID4B SIN3A DMAP1 ZNF48 SLC30A9 ZNF121 ANKRD9 LOC105370679 RCOR1 CINP TECPR2 ZNF839 AMN
GH14I102522 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 15.8 -16.2 -16195 6 MLX YBX1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC GLIS1 RCOR2 RCOR1 WDR20 TECPR2 MOK ANKRD9 ZNF839 CDC42BPB TRAF3 RNU6-244P DYNC1H1
GH14I102530 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 17.9 -21.8 -21811 2.5 HDAC1 NFXL1 RFX5 HSF1 ZSCAN5C ZNF143 RCOR1 ATF7 ZHX1 SMARCA5 ANKRD9 RCOR1 TRAF3 MIR4309 LOC105370680
GH14I102503 Enhancer 1.3 Ensembl ENCODE dbSUPER 18.6 +5.0 5026 2.4 HDAC1 ARNT KLF17 ZBTB40 TCF12 ZNF766 GLIS2 GATA2 CREM PAF1 ANKRD9 RCOR1 TECPR2 CINP ZNF839 RNU6-244P
GH14I102516 Enhancer 1.4 Ensembl ENCODE dbSUPER 16.9 -7.4 -7386 2 HDGF ARID4B SIN3A DMAP1 ZNF48 ZNF213 ZNF143 SP3 YY2 REST LOC105370680 ANKRD9 RCOR1 TECPR2 LOC105370679
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ANKRD9 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ANKRD9 gene promoter:

Genomic Locations for ANKRD9 Gene

Genomic Locations for ANKRD9 Gene
chr14:102,501,760-102,509,799
(GRCh38/hg38)
Size:
8,040 bases
Orientation:
Minus strand
chr14:102,973,179-102,976,136
(GRCh37/hg19)

Genomic View for ANKRD9 Gene

Genes around ANKRD9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD9 Gene

Proteins for ANKRD9 Gene

  • Protein details for ANKRD9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96BM1-ANKR9_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 9
    Protein Accession:
    Q96BM1
    Secondary Accessions:
    • A8K753

    Protein attributes for ANKRD9 Gene

    Size:
    317 amino acids
    Molecular mass:
    34295 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD9 Gene

Post-translational modifications for ANKRD9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ANKRD9 Gene

Domains & Families for ANKRD9 Gene

Gene Families for ANKRD9 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ANKRD9 Gene

Suggested Antigen Peptide Sequences for ANKRD9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ANKRD9: view

No data available for UniProtKB/Swiss-Prot for ANKRD9 Gene

Function for ANKRD9 Gene

Phenotypes From GWAS Catalog for ANKRD9 Gene

genes like me logo Genes that share phenotypes with ANKRD9: view

Animal Models for ANKRD9 Gene

MGI Knock Outs for ANKRD9:

Animal Model Products

  • Taconic Biosciences Mouse Models for ANKRD9

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ANKRD9 Gene

Localization for ANKRD9 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ANKRD9 gene
Compartment Confidence
cytosol 5
nucleus 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for ANKRD9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005829 cytosol TAS --
genes like me logo Genes that share ontologies with ANKRD9: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for ANKRD9 Gene

Pathways & Interactions for ANKRD9 Gene

SuperPathways for ANKRD9 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043687 post-translational protein modification TAS --
genes like me logo Genes that share ontologies with ANKRD9: view

No data available for Pathways by source and SIGNOR curated interactions for ANKRD9 Gene

Drugs & Compounds for ANKRD9 Gene

No Compound Related Data Available

Transcripts for ANKRD9 Gene

Unigene Clusters for ANKRD9 Gene

Ankyrin repeat domain 9:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD9 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b
SP1: - -
SP2: - -
SP3: - - - -
SP4:
SP5: -
SP6:

Relevant External Links for ANKRD9 Gene

GeneLoc Exon Structure for
ANKRD9
ECgene alternative splicing isoforms for
ANKRD9

Expression for ANKRD9 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ANKRD9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ANKRD9 Gene

This gene is overexpressed in Muscle - Skeletal (x6.1) and Heart - Left Ventricle (x4.5).

Protein differential expression in normal tissues from HIPED for ANKRD9 Gene

This gene is overexpressed in Liver, secretome (41.5) and Breast (27.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ANKRD9 Gene



Protein tissue co-expression partners for ANKRD9 Gene

NURSA nuclear receptor signaling pathways regulating expression of ANKRD9 Gene:

ANKRD9

SOURCE GeneReport for Unigene cluster for ANKRD9 Gene:

Hs.432945

Evidence on tissue expression from TISSUES for ANKRD9 Gene

  • Muscle(4.4)
  • Intestine(4.1)
  • Stomach(2.8)
genes like me logo Genes that share expression patterns with ANKRD9: view

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKRD9 Gene

Orthologs for ANKRD9 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKRD9 33 34
  • 99.16 (n)
cow
(Bos Taurus)
Mammalia ANKRD9 33 34
  • 89.7 (n)
dog
(Canis familiaris)
Mammalia ANKRD9 33 34
  • 89.35 (n)
rat
(Rattus norvegicus)
Mammalia Ankrd9 33
  • 82.17 (n)
mouse
(Mus musculus)
Mammalia Ankrd9 33 16 34
  • 79.64 (n)
oppossum
(Monodelphis domestica)
Mammalia ANKRD9 34
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ANKRD9 34
  • 70 (a)
OneToOne
chicken
(Gallus gallus)
Aves ANKRD9 33 34
  • 69.93 (n)
lizard
(Anolis carolinensis)
Reptilia ANKRD9 34
  • 63 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd9 33
  • 60.36 (n)
zebrafish
(Danio rerio)
Actinopterygii ankrd9 33 34
  • 56.77 (n)
Species where no ortholog for ANKRD9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD9 Gene

ENSEMBL:
Gene Tree for ANKRD9 (if available)
TreeFam:
Gene Tree for ANKRD9 (if available)

Paralogs for ANKRD9 Gene

No data available for Paralogs for ANKRD9 Gene

Variants for ANKRD9 Gene

Sequence variations from dbSNP and Humsavar for ANKRD9 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1000045356 -- 102,508,644(-) TT/TTT 5_prime_UTR_variant, intron_variant
rs1000084441 -- 102,503,433(-) G/A downstream_transcript_variant
rs1000199947 -- 102,511,028(-) T/G upstream_transcript_variant
rs1000266126 -- 102,506,138(-) C/T 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1000428938 -- 102,511,676(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD9 Gene

Variant ID Type Subtype PubMed ID
dgv263n27 CNV gain 19166990
esv3635555 CNV gain 21293372
nsv1049544 CNV gain 25217958
nsv1069821 CNV deletion 25765185
nsv1118293 CNV deletion 24896259
nsv1126377 CNV deletion 24896259
nsv1160203 CNV deletion 26073780
nsv470671 CNV gain 18288195
nsv522878 CNV loss 19592680
nsv565948 CNV gain 21841781
nsv832880 CNV loss 17160897
nsv952254 CNV deletion 24416366

Variation tolerance for ANKRD9 Gene

Gene Damage Index Score: 0.45; 9.86% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ANKRD9 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ANKRD9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD9 Gene

Disorders for ANKRD9 Gene

Additional Disease Information for ANKRD9

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for ANKRD9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD9 Gene

Publications for ANKRD9 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  2. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R … Weissenbach J (Nature 2003) 3 4 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  5. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. (PMID: 24952745) Arking DE … Newton-Cheh C (Nature genetics 2014) 3 58

Products for ANKRD9 Gene

Sources for ANKRD9 Gene

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