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Aliases for ANKRD39 Gene

Aliases for ANKRD39 Gene

  • Ankyrin Repeat Domain 39 2 3 5

External Ids for ANKRD39 Gene

Previous GeneCards Identifiers for ANKRD39 Gene

  • GC02M096936
  • GC02M096865
  • GC02M097502
  • GC02M091473

Summaries for ANKRD39 Gene

GeneCards Summary for ANKRD39 Gene

ANKRD39 (Ankyrin Repeat Domain 39) is a Protein Coding gene. An important paralog of this gene is GABPB2.

Additional gene information for ANKRD39 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD39 Gene

Genomics for ANKRD39 Gene

GeneHancer (GH) Regulatory Elements for ANKRD39 Gene

Promoters and enhancers for ANKRD39 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I096856 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 550.8 -0.4 -420 3.7 HDGF HNRNPUL1 PKNOX1 ZFP64 ARID4B NEUROD1 SIN3A DMAP1 ZNF2 YY1 ANKRD39 ANKRD23 SNRNP200 KANSL3 STARD7-AS1 ANKRD36 SEMA4C LMAN2L GC02P096839
GH02I096905 Enhancer 1.1 Ensembl ENCODE dbSUPER 13 -49.1 -49125 2.5 KLF1 USF1 NFIB SIN3A ZIC2 ZFHX2 GLIS2 SCRT2 EGR2 SP3 FAM178B SEMA4C ANKRD39 ANKRD23 SNRNP200 LOC101927053
GH02I096908 Enhancer 0.2 dbSUPER 13 -51.8 -51798 1.8 SEMA4C ANKRD23 ANKRD39 FAM178B CNNM3 SNRNP200 LOC100506076 LOC101927053
GH02I096866 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 0.4 -10.8 -10791 5.3 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A DMAP1 ZBTB7B YY1 SLC30A9 SEMA4C ANKRD36 FAM178B LMAN2L SNRNP200 GPAT2P2 C2orf92 ANKRD36B ANKRD39 GC02P096839
GH02I096861 Enhancer 0.9 Ensembl 0.8 -4.1 -4119 0.8 FOXA2 MLX ARID4B DMAP1 ETS1 YY1 SLC30A9 ATF7 PAF1 RXRA CNNM3 ANKRD39 SEMA4C GC02P096839
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ANKRD39 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ANKRD39 gene promoter:

Genomic Locations for ANKRD39 Gene

Genomic Locations for ANKRD39 Gene
21,485 bases
Minus strand

Genomic View for ANKRD39 Gene

Genes around ANKRD39 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD39 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD39 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD39 Gene

Proteins for ANKRD39 Gene

  • Protein details for ANKRD39 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein 39
    Protein Accession:
    Secondary Accessions:
    • Q59FU2
    • Q8N5X5
    • Q9P0S5

    Protein attributes for ANKRD39 Gene

    183 amino acids
    Molecular mass:
    19651 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAF36120.1; Type=Frameshift; Positions=172; Evidence={ECO:0000305}; Sequence=BAD92604.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ANKRD39 Gene

Post-translational modifications for ANKRD39 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD39 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD39 Gene

Domains & Families for ANKRD39 Gene

Gene Families for ANKRD39 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ANKRD39 Gene

Suggested Antigen Peptide Sequences for ANKRD39 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the ANKRD39 family.
  • Belongs to the ANKRD39 family.
genes like me logo Genes that share domains with ANKRD39: view

Function for ANKRD39 Gene

Gene Ontology (GO) - Molecular Function for ANKRD39 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with ANKRD39: view
genes like me logo Genes that share phenotypes with ANKRD39: view

Animal Model Products

miRNA for ANKRD39 Gene

miRTarBase miRNAs that target ANKRD39

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKRD39 Gene

Localization for ANKRD39 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ANKRD39 gene
Compartment Confidence
cytosol 4
nucleus 3
extracellular 2
plasma membrane 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ANKRD39 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with ANKRD39: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ANKRD39 Gene

Pathways & Interactions for ANKRD39 Gene

SuperPathways for ANKRD39 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD39 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ANKRD39: view

No data available for Pathways by source and SIGNOR curated interactions for ANKRD39 Gene

Drugs & Compounds for ANKRD39 Gene

No Compound Related Data Available

Transcripts for ANKRD39 Gene

mRNA/cDNA for ANKRD39 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(177) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKRD39 Gene

Ankyrin repeat domain 39:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD39 Gene

No ASD Table

Relevant External Links for ANKRD39 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKRD39 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ANKRD39 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ANKRD39 Gene

NURSA nuclear receptor signaling pathways regulating expression of ANKRD39 Gene:


SOURCE GeneReport for Unigene cluster for ANKRD39 Gene:

genes like me logo Genes that share expression patterns with ANKRD39: view

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKRD39 Gene

Orthologs for ANKRD39 Gene

This gene was present in the common ancestor of animals.

Orthologs for ANKRD39 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ANKRD39 33 34
  • 99.82 (n)
(Bos Taurus)
Mammalia ANKRD39 33 34
  • 88.52 (n)
(Canis familiaris)
Mammalia ANKRD39 33 34
  • 87.07 (n)
(Mus musculus)
Mammalia Ankrd39 33 16 34
  • 87.07 (n)
(Rattus norvegicus)
Mammalia Ankrd39 33
  • 86.34 (n)
(Ornithorhynchus anatinus)
Mammalia ANKRD39 34
  • 57 (a)
(Anolis carolinensis)
Reptilia ANKRD39 34
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd39 33
  • 58.81 (n)
Str.15021 33
(Danio rerio)
Actinopterygii ankrd39 33 34
  • 58.28 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG44001 33
  • 55.35 (n)
CG31919 34
  • 23 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009205 33
  • 50.57 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 43 (a)
Species where no ortholog for ANKRD39 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD39 Gene

Gene Tree for ANKRD39 (if available)
Gene Tree for ANKRD39 (if available)

Paralogs for ANKRD39 Gene

Paralogs for ANKRD39 Gene

(9) SIMAP similar genes for ANKRD39 Gene using alignment to 1 proteins: Pseudogenes for ANKRD39 Gene

genes like me logo Genes that share paralogs with ANKRD39: view

Variants for ANKRD39 Gene

Sequence variations from dbSNP and Humsavar for ANKRD39 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000220260 -- 96,850,828(-) T/TT intron_variant
rs1000236293 -- 96,857,066(-) G/C intron_variant
rs1000300197 -- 96,854,041(-) C/T intron_variant
rs1000570784 -- 96,850,492(-) T/C intron_variant
rs1000649302 -- 96,854,327(-) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD39 Gene

Variant ID Type Subtype PubMed ID
dgv607e201 CNV deletion 23290073
esv3425717 CNV duplication 20981092
esv3591694 CNV loss 21293372
esv5003 OTHER complex 18987735
nsv1135873 CNV deletion 24896259
nsv526313 CNV loss 19592680

Variation tolerance for ANKRD39 Gene

Residual Variation Intolerance Score: 65.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.66; 14.06% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ANKRD39 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD39 Gene

Disorders for ANKRD39 Gene

Additional Disease Information for ANKRD39

No disorders were found for ANKRD39 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD39 Gene

Publications for ANKRD39 Gene

  1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang QH … Chen Z (Genome research 2000) 2 3 4 58
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 3 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  5. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PMID: 23824909) Chen Y … Ge F (Molecular & cellular proteomics : MCP 2013) 3 58

Products for ANKRD39 Gene

Sources for ANKRD39 Gene

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