Aliases for ANKRD36C Gene
Aliases for ANKRD36C Gene
External Ids for ANKRD36C Gene
- HGNC: 32946
- Entrez Gene: 400986
- Ensembl: ENSG00000174501
- UniProtKB: Q5JPF3
Previous GeneCards Identifiers for ANKRD36C Gene
- GC02M096515
Summaries for ANKRD36C Gene
GeneCards Summary for ANKRD36C Gene
ANKRD36C (Ankyrin Repeat Domain 36C) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ion channel inhibitor activity. An important paralog of this gene is ANKRD36.
Additional gene information for ANKRD36C Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD36C Gene
Genomics for ANKRD36C Gene
GeneHancer (GH) Regulatory Elements for ANKRD36C Gene
Promoters and enhancers for ANKRD36C Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH02J095990 | Promoter/Enhancer | 1.9 | EPDnew Ensembl ENCODE | 650.7 | +0.3 | 259 | 2.9 | PKNOX1 ATF1 FOXA2 ARID4B SIN3A DMAP1 ZNF2 ZNF48 GLIS2 ZNF213 | ANKRD36C PIR48420 ADRA2B GPAT2 | |
| GH02J095855 | Promoter | 0.5 | EPDnew | 650.1 | +136.9 | 136905 | 0.1 | ANKRD36C GC02P095852 GC02P095853 PIR60512 GC02P095854 GC02P095850 GC02P095884 GC02M095672 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ANKRD36C on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for ANKRD36C Gene
Genomic Locations for ANKRD36C Gene
- chr2:95,827,619-95,992,320
- (GRCh38/hg38)
- Size:
- 164,702 bases
- Orientation:
- Minus strand
- chr2:96,514,587-96,657,980
- (GRCh37/hg19)
Genomic View for ANKRD36C Gene
Genes around ANKRD36C on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q11.1 by Entrez Gene
- 2q11.1 by HGNC
- 2q11.1 by Ensembl
ANKRD36C Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ANKRD36C Gene
Proteins for ANKRD36C Gene
-
Protein details for ANKRD36C Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5JPF3-AN36C_HUMAN
- Recommended name:
- Ankyrin repeat domain-containing protein 36C
- Protein Accession:
- Q5JPF3
- C9JZ08
- Q15694
- Q53S06
- Q658V2
Protein attributes for ANKRD36C Gene
- Size:
- 1778 amino acids
- Molecular mass:
- 199748 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAB02177.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AAB02177.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=AAY24080.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAH56324.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};
Protein Expression for ANKRD36C Gene
Post-translational modifications for ANKRD36C Gene
Other Protein References for ANKRD36C Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ANKRD36C
- Invitrogen Antibodies for ANKRD36C
- Search GeneTex for Antibodies for ANKRD36C
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for ANKRD36C
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- Novus Biologicals proteins for ANKRD36C
- Search GeneTex for Proteins for ANKRD36C
Assay Products
No data available for DME Specific Peptides for ANKRD36C Gene
Domains & Families for ANKRD36C Gene
Gene Families for ANKRD36C Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for ANKRD36C Gene
- InterPro:
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
Q5JPF3- Family:
-
- Belongs to the ANKRD36 family.
No data available for Suggested Antigen Peptide Sequences for ANKRD36C Gene
Function for ANKRD36C Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008200 | ion channel inhibitor activity | NAS | 8608414 |
Phenotypes for ANKRD36C Gene
- GenomeRNAi human phenotypes for ANKRD36C:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ANKRD36C
-
CRISPR Products
- Browse CRISPR knockouts for ANKRD36C
- genomics-online: gRNA clones - Search results for available ANKRD36C gene related products
- Applied Biological Materials CRISPR for ANKRD36C
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
Inhibitory RNA Products
- genomics-online: shRNA clones - Search results for available ANKRD36C gene related products
Clone Products
- VectorBuilder custom plasmid, inducible vectors for ANKRD36C
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ANKRD36C
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available ANKRD36C gene related products
- orf clones - Search results for available ANKRD36C gene related products
- Applied Biological Materials Clones for ANKRD36C
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ANKRD36C Gene
Localization for ANKRD36C Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 1 |
- Cytosol (2)
- Nucleus (2)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD36C Gene
Pathways & Interactions for ANKRD36C Gene
No Data Available
Interacting Proteins for ANKRD36C Gene
GPS-Prot Interaction Network for ANKRD36C
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0065009 | regulation of molecular function | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for ANKRD36C Gene
Transcripts for ANKRD36C Gene
mRNA/cDNA for ANKRD36C Gene
- (6) Additional mRNA sequences :
- (2) REFSEQ mRNAs :
- (8) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000295246 2272 bps (uc061lue.1)
- ENST00000456556 5428 bps (uc061lua.1)
- ENST00000488721 2740 bps (uc061lub.1)
- ENST00000528268 1907 bps (uc061luf.1)
- ENST00000531153 2811 bps (uc061luc.1)
Unigene Clusters for ANKRD36C Gene
CRISPR Products
- Browse CRISPR knockouts for ANKRD36C
- genomics-online: gRNA clones - Search results for available ANKRD36C gene related products
- Applied Biological Materials CRISPR for ANKRD36C
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
Inhibitory RNA Products
- genomics-online: shRNA clones - Search results for available ANKRD36C gene related products
Clone Products
- VectorBuilder custom plasmid, inducible vectors for ANKRD36C
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ANKRD36C
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available ANKRD36C gene related products
- orf clones - Search results for available ANKRD36C gene related products
- Applied Biological Materials Clones for ANKRD36C
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for ANKRD36C Gene
mRNA differential expression in normal tissues according to GTEx for ANKRD36C Gene
This gene is overexpressed in Minor Salivary Gland (x5.7).
This gene is overexpressed in Blymphocyte (19.6), CD8 Tcells (17.6), Monocytes (15.5), and Ovary (6.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ANKRD36C Gene
NURSA nuclear receptor signaling pathways regulating expression of ANKRD36C Gene:
ANKRD36CSOURCE GeneReport for Unigene cluster for ANKRD36C Gene:
Hs.646318Evidence on tissue expression from TISSUES for ANKRD36C Gene
- Stomach(4.4)
- Lymph node(4)
- Nervous system(2.8)
- Intestine(2.5)
Primer Products
- genomics-online: primer clones - Search results for available ANKRD36C gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKRD36C Gene
Orthologs for ANKRD36C Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ANKRD36 33 |
|
||
| ANKRD36C 34 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | -- 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany | |||
| -- 34 |
|
ManyToMany | |||
| -- 34 |
|
ManyToMany | |||
| -- 34 |
|
ManyToMany | |||
| -- 34 |
|
ManyToMany | |||
| -- 34 |
|
ManyToMany | |||
| -- 34 |
|
ManyToMany | |||
| mouse (Mus musculus) |
Mammalia | Gm15319 34 |
|
ManyToMany | |
| cow (Bos Taurus) |
Mammalia | -- 34 |
|
OneToMany | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
ManyToMany | |
| chicken (Gallus gallus) |
Aves | -- 34 |
|
OneToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
ManyToMany | |
| zebrafish (Danio rerio) |
Actinopterygii | ANKRD7 34 |
|
OneToMany |
- Species where no ortholog for ANKRD36C was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for ANKRD36C Gene
- ENSEMBL:
- Gene Tree for ANKRD36C (if available)
- TreeFam:
- Gene Tree for ANKRD36C (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ANKRD36C: view image
Paralogs for ANKRD36C Gene
Paralogs for ANKRD36C Gene
- ANKRD36 5
- ANKRD36B 5
- ANKRD26 5
- ANKRD62 5
- ANKRD30B 5
- ANKRD30A 5
- CCDC144A 5
- ENSG00000266302 5
- ANKRD20A8P 5
- ANKRD20A1 5
- ANKRD20A3 5
- ANKRD20A4 5
- ANKRD20A2 5
- ANKRD18A 5
- ANKRD18B 5
- POTEA 5
- POTEE 5
- POTEF 5
- POTEI 5
- POTEB3 5
- POTED 5
- POTEB 5
- LOC102723502 5
- LOC100288966 5
- POTEB2 5
- POTEC 5
- POTEM 5
- POTEH 5
- POTEG 5
- ANKRD30BL 5
- ANKRD7 5
(25) SIMAP similar genes for ANKRD36C Gene using alignment to 7 proteins:
- AN36C_HUMAN
- E9PJI0_HUMAN
- F8WEX4_HUMAN
- H0YDI7_HUMAN
- H7BXK8_HUMAN
- H7C425_HUMAN
- I1Z9D4_HUMAN
Pseudogenes.org Pseudogenes for ANKRD36C Gene
Variants for ANKRD36C Gene
| SNP ID | Clin | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000005662 | -- | 95,859,034(-) | G/A | intron_variant | |
| rs1000040965 | -- | 95,849,508(-) | G/C | downstream_transcript_variant | |
| rs1000108293 | -- | 95,950,066(-) | G/A | intron_variant | |
| rs1000141103 | -- | 95,858,701(-) | T/A | intron_variant | |
| rs1000218684 | -- | 95,957,193(-) | A/C | intron_variant |
Gene Damage Index Score:
9.73;
89.35% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ANKRD36C Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ANKRD36C
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ANKRD36C Gene
Disorders for ANKRD36C Gene
Additional Disease Information for ANKRD36C
No disorders were found for ANKRD36C Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD36C Gene
Publications for ANKRD36C Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- Inhibitors of renal epithelial phosphate transport in tumor-induced osteomalacia and uremia. (PMID: 8608414) Kumar R … Cai Q (Proceedings of the Association of American Physicians 1995) 3 4 58
- Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H … Mohammed S (Journal of proteome research 2013) 4 58
- The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 58
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 4 58
Products for ANKRD36C Gene
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- VectorBuilder custom plasmid, inducible vectors for ANKRD36C
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for ANKRD36C
- Search GeneTex for Proteins for ANKRD36C
- genomics-online: cdna clones - Search results for available ANKRD36C gene related products
- orf clones - Search results for available ANKRD36C gene related products
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Sources for ANKRD36C Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio