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Aliases for ANKRD34C Gene

Aliases for ANKRD34C Gene

  • Ankyrin Repeat Domain 34C 2 3 5
  • Ankyrin Repeat Domain-Containing Protein 34C 3

External Ids for ANKRD34C Gene

Previous GeneCards Identifiers for ANKRD34C Gene

  • GC15P077372
  • GC15P079585
  • GC15P056333

Summaries for ANKRD34C Gene

GeneCards Summary for ANKRD34C Gene

ANKRD34C (Ankyrin Repeat Domain 34C) is a Protein Coding gene. An important paralog of this gene is ANKRD34A.

Additional gene information for ANKRD34C Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD34C Gene

Genomics for ANKRD34C Gene

GeneHancer (GH) Regulatory Elements for ANKRD34C Gene

Promoters and enhancers for ANKRD34C Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J079314 Enhancer 0.7 ENCODE 10.9 +32.2 32210 0.2 NCOA3 PKNOX1 CLOCK ESRRA NFIB NEUROD1 SIN3A MTA3 CTBP1 GATA3 ANKRD34C TMED3 GC15P079414
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ANKRD34C on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ANKRD34C gene promoter:

Genomic Locations for ANKRD34C Gene

Genomic Locations for ANKRD34C Gene
15,436 bases
Plus strand

Genomic View for ANKRD34C Gene

Genes around ANKRD34C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD34C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD34C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD34C Gene

Proteins for ANKRD34C Gene

  • Protein details for ANKRD34C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein 34C
    Protein Accession:
    Secondary Accessions:
    • H3BNM1

    Protein attributes for ANKRD34C Gene

    535 amino acids
    Molecular mass:
    58256 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD34C Gene

Post-translational modifications for ANKRD34C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD34C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD34C Gene

Domains & Families for ANKRD34C Gene

Gene Families for ANKRD34C Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ANKRD34C Gene

Suggested Antigen Peptide Sequences for ANKRD34C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the ANKRD34 family.
  • Belongs to the ANKRD34 family.
genes like me logo Genes that share domains with ANKRD34C: view

Function for ANKRD34C Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ANKRD34C Gene

Localization for ANKRD34C Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ANKRD34C gene
Compartment Confidence
nucleus 3
mitochondrion 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD34C Gene

Pathways & Interactions for ANKRD34C Gene

SuperPathways for ANKRD34C Gene

No Data Available

Interacting Proteins for ANKRD34C Gene

Gene Ontology (GO) - Biological Process for ANKRD34C Gene


No data available for Pathways by source and SIGNOR curated interactions for ANKRD34C Gene

Drugs & Compounds for ANKRD34C Gene

No Compound Related Data Available

Transcripts for ANKRD34C Gene

mRNA/cDNA for ANKRD34C Gene

(3) Selected AceView cDNA sequences:
(3) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKRD34C Gene

Ankyrin repeat domain 34C:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD34C Gene

No ASD Table

Relevant External Links for ANKRD34C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKRD34C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ANKRD34C Gene

mRNA differential expression in normal tissues according to GTEx for ANKRD34C Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x8.1), Brain - Hypothalamus (x7.3), Brain - Frontal Cortex (BA9) (x6.3), Brain - Cerebellum (x5.8), Brain - Cortex (x4.5), and Brain - Anterior cingulate cortex (BA24) (x4.5).

Protein differential expression in normal tissues from HIPED for ANKRD34C Gene

This gene is overexpressed in Peripheral blood mononuclear cells (61.2) and Retina (7.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ANKRD34C Gene

Protein tissue co-expression partners for ANKRD34C Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ANKRD34C Gene:


SOURCE GeneReport for Unigene cluster for ANKRD34C Gene:

genes like me logo Genes that share expression patterns with ANKRD34C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKRD34C Gene

Orthologs for ANKRD34C Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD34C Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ANKRD34C 34 33
  • 99.5 (n)
(Rattus norvegicus)
Mammalia Ankrd34c 33
  • 86.68 (n)
(Mus musculus)
Mammalia Ankrd34c 16 34 33
  • 86.43 (n)
(Canis familiaris)
Mammalia ANKRD34C 34 33
  • 85.14 (n)
(Bos Taurus)
Mammalia ANKRD34C 34 33
  • 84.52 (n)
(Monodelphis domestica)
Mammalia ANKRD34C 34
  • 80 (a)
(Gallus gallus)
Aves ANKRD34C 34 33
  • 65.09 (n)
(Danio rerio)
Actinopterygii ANKRD34C 34
  • 64 (a)
LOC566743 33
  • 63.93 (n)
Species where no ortholog for ANKRD34C was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD34C Gene

Gene Tree for ANKRD34C (if available)
Gene Tree for ANKRD34C (if available)
Evolutionary constrained regions (ECRs) for ANKRD34C: view image

Paralogs for ANKRD34C Gene

Paralogs for ANKRD34C Gene

(2) SIMAP similar genes for ANKRD34C Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ANKRD34C: view

Variants for ANKRD34C Gene

Sequence variations from dbSNP and Humsavar for ANKRD34C Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000373787 -- 79,297,862(+) G/A 3_prime_UTR_variant
rs1000421750 -- 79,285,278(+) C/T intron_variant
rs1000430460 -- 79,290,754(+) C/T intron_variant
rs1000649793 -- 79,298,192(+) T/G 3_prime_UTR_variant
rs1000844575 -- 79,280,936(+) G/A upstream_transcript_variant

Variation tolerance for ANKRD34C Gene

Gene Damage Index Score: 1.71; 32.59% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ANKRD34C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ANKRD34C Gene

Disorders for ANKRD34C Gene

Additional Disease Information for ANKRD34C

No disorders were found for ANKRD34C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD34C Gene

Publications for ANKRD34C Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58

Products for ANKRD34C Gene

Sources for ANKRD34C Gene

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