Aliases for ANKRD20A4 Gene

Aliases for ANKRD20A4 Gene

  • Ankyrin Repeat Domain 20 Family Member A4 2 3 5
  • Ankyrin Repeat Domain-Containing Protein 20A4 3 4
  • Ankyrin Repeat Domain 20 Family, Member A4 2

External Ids for ANKRD20A4 Gene

Previous GeneCards Identifiers for ANKRD20A4 Gene

  • GC09U900751
  • GC09P068672
  • GC09P069381
  • GC09M039336

Summaries for ANKRD20A4 Gene

GeneCards Summary for ANKRD20A4 Gene

ANKRD20A4 (Ankyrin Repeat Domain 20 Family Member A4) is a Protein Coding gene. An important paralog of this gene is ANKRD20A2.

Additional gene information for ANKRD20A4 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ANKRD20A4 Gene

Genomics for ANKRD20A4 Gene

GeneHancer (GH) Regulatory Elements for ANKRD20A4 Gene

Promoters and enhancers for ANKRD20A4 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J064369 Promoter 1.2 EPDnew Ensembl 750.6 -0.2 -193 2.4 CTCF CTBP1 ZBTB8A TRIM22 ZNF143 LARP7 SP2 ZNF561 ZSCAN29 ZBTB20 AB372696-003 ANKRD20A4 ANKRD20A4-ANKRD20A20P-001 NONHSAG052292.2-004 lnc-FOXD4L5-12 piR-42891-004
GH09J064411 Enhancer 0.2 Ensembl 0.3 +42.5 42507 0.2 ANKRD20A20P piR-59853-003 piR-61304-003 ANKRD20A4 ANKRD20A4-ANKRD20A20P-001
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ANKRD20A4 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ANKRD20A4 gene promoter:
  • CUTL1
  • Evi-1
  • POU2F1
  • POU2F1a
  • POU2F1b
  • POU2F1c
  • TBP
  • TGIF
  • YY1

Genomic Locations for ANKRD20A4 Gene

Genomic Locations for ANKRD20A4 Gene
43,749 bases
Plus strand
43,749 bases
Plus strand

Genomic View for ANKRD20A4 Gene

Genes around ANKRD20A4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD20A4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD20A4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD20A4 Gene

Proteins for ANKRD20A4 Gene

  • Protein details for ANKRD20A4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein 20A4
    Protein Accession:

    Protein attributes for ANKRD20A4 Gene

    823 amino acids
    Molecular mass:
    94149 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD20A4 Gene

Post-translational modifications for ANKRD20A4 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD20A4 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD20A4 Gene

Domains & Families for ANKRD20A4 Gene

Gene Families for ANKRD20A4 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ANKRD20A4 Gene

Suggested Antigen Peptide Sequences for ANKRD20A4 Gene

GenScript: Design optimal peptide antigens:
  • Ankyrin repeat domain-containing protein 20A4 (A20A4_HUMAN)
genes like me logo Genes that share domains with ANKRD20A4: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ANKRD20A4 Gene

Function for ANKRD20A4 Gene

Animal Model Products

CRISPR Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ANKRD20A4 Gene

Localization for ANKRD20A4 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ANKRD20A4 gene
Compartment Confidence
nucleus 2
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ANKRD20A4 Gene

Pathways & Interactions for ANKRD20A4 Gene

PathCards logo

SuperPathways for ANKRD20A4 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD20A4 Gene


No data available for Pathways by source and SIGNOR curated interactions for ANKRD20A4 Gene

Drugs & Compounds for ANKRD20A4 Gene

No Compound Related Data Available

Transcripts for ANKRD20A4 Gene

mRNA/cDNA for ANKRD20A4 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD20A4 Gene

No ASD Table

Relevant External Links for ANKRD20A4 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKRD20A4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ANKRD20A4 Gene

mRNA differential expression in normal tissues according to GTEx for ANKRD20A4 Gene

This gene is overexpressed in Testis (x4.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ANKRD20A4 Gene

NURSA nuclear receptor signaling pathways regulating expression of ANKRD20A4 Gene:


SOURCE GeneReport for Unigene cluster for ANKRD20A4 Gene:

genes like me logo Genes that share expression patterns with ANKRD20A4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKRD20A4 Gene

Orthologs for ANKRD20A4 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD20A4 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC738297 32
  • 98.5 (n)
-- 33
  • 97 (a)
(Canis familiaris)
Mammalia -- 33
  • 42 (a)
-- 33
  • 41 (a)
-- 33
  • 39 (a)
-- 33
  • 29 (a)
-- 33
  • 16 (a)
-- 33
  • 16 (a)
-- 33
  • 15 (a)
-- 33
  • 14 (a)
(Mus musculus)
Mammalia Gm1758 33
  • 36 (a)
(Bos Taurus)
Mammalia -- 33
  • 33 (a)
(Ornithorhynchus anatinus)
Mammalia -- 33
  • 11 (a)
(Gallus gallus)
Aves -- 33
  • 18 (a)
(Anolis carolinensis)
Reptilia -- 33
  • 41 (a)
(Danio rerio)
Actinopterygii ANKRD7 33
  • 9 (a)
Species where no ortholog for ANKRD20A4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD20A4 Gene

Gene Tree for ANKRD20A4 (if available)
Gene Tree for ANKRD20A4 (if available)

Paralogs for ANKRD20A4 Gene

(19) SIMAP similar genes for ANKRD20A4 Gene using alignment to 1 proteins:

  • A20A4_HUMAN
genes like me logo Genes that share paralogs with ANKRD20A4: view

Variants for ANKRD20A4 Gene

Sequence variations from dbSNP and Humsavar for ANKRD20A4 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000915685 -- 64,391,666(+) A/G intron_variant
rs1001066736 -- 64,413,103(+) AATAAATAAA/AATAAA downstream_transcript_variant
rs1001077805 -- 64,412,206(+) A/G/T 3_prime_UTR_variant
rs1001345240 -- 64,390,766(+) G/A/C coding_sequence_variant, missense_variant
rs1001575260 -- 64,409,712(+) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD20A4 Gene

Variant ID Type Subtype PubMed ID
dgv4353e59 CNV duplication 20981092
dgv7653n100 CNV gain 25217958
dgv7654n100 CNV gain 25217958
esv3345323 CNV duplication 20981092
esv3354240 CNV duplication 20981092
esv3365575 CNV duplication 20981092
esv3367902 CNV duplication 20981092
esv3385387 CNV duplication 20981092
esv3390584 CNV duplication 20981092
esv3415864 CNV duplication 20981092
esv3420472 CNV duplication 20981092
esv3430467 CNV duplication 20981092
esv3431814 CNV duplication 20981092
esv3446655 CNV duplication 20981092
nsv1115809 CNV duplication 24896259
nsv1129003 CNV duplication 24896259
nsv1132728 CNV duplication 24896259
nsv1141631 CNV duplication 24896259
nsv1146991 CNV duplication 26484159
nsv1151388 CNV duplication 26484159
nsv1152173 CNV duplication 26484159
nsv951747 CNV duplication 24416366
nsv969570 CNV duplication 23825009
nsv969572 CNV duplication 23825009
nsv969573 CNV duplication 23825009
nsv969667 CNV duplication 23825009
nsv969668 CNV duplication 23825009
nsv969670 CNV duplication 23825009
nsv969671 CNV duplication 23825009
nsv973263 CNV duplication 23825009
nsv973266 CNV duplication 23825009
nsv973267 CNV duplication 23825009
nsv973268 CNV duplication 23825009
nsv973344 CNV duplication 23825009
nsv973346 CNV duplication 23825009
nsv973347 CNV duplication 23825009
nsv973614 CNV duplication 23825009
nsv973615 CNV duplication 23825009
nsv973616 CNV duplication 23825009
nsv973617 CNV duplication 23825009
nsv973618 CNV duplication 23825009
nsv973619 CNV duplication 23825009
nsv973709 CNV duplication 23825009
nsv973711 CNV duplication 23825009
nsv973712 CNV duplication 23825009
nsv982243 CNV duplication 23825009
nsv982292 CNV duplication 23825009
nsv982422 CNV duplication 23825009
nsv982424 CNV duplication 23825009
nsv982425 CNV duplication 23825009
nsv982508 CNV duplication 23825009
nsv982510 CNV duplication 23825009
nsv982511 CNV duplication 23825009
nsv982513 CNV duplication 23825009

Variation tolerance for ANKRD20A4 Gene

Gene Damage Index Score: 3.66; 56.93% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ANKRD20A4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD20A4 Gene

Disorders for ANKRD20A4 Gene

Additional Disease Information for ANKRD20A4

No disorders were found for ANKRD20A4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD20A4 Gene

Publications for ANKRD20A4 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4 56

Products for ANKRD20A4 Gene

Sources for ANKRD20A4 Gene