Aliases for ANKRD16 Gene
External Ids for ANKRD16 Gene
Previous GeneCards Identifiers for ANKRD16 Gene
GeneCards Summary for ANKRD16 Gene
ANKRD16 (Ankyrin Repeat Domain 16) is a Protein Coding gene. An important paralog of this gene is ASB1.
UniProtKB/Swiss-Prot Summary for ANKRD16 Gene
Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides.