Aliases for ANKRD12 Gene
External Ids for ANKRD12 Gene
Previous GeneCards Identifiers for ANKRD12 Gene
This gene encodes a member of the ankyrin repeats-containing cofactor family. These proteins may inhibit the transcriptional activity of nuclear receptors through the recruitment of histone deacetylases. The encoded protein interacts with p160 coactivators and also represses transcription mediated by the coactivator alteration/deficiency in activation 3 (ADA3). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
GeneCards Summary for ANKRD12 Gene
ANKRD12 (Ankyrin Repeat Domain 12) is a Protein Coding gene. An important paralog of this gene is ANKRD11.
UniProtKB/Swiss-Prot for ANKRD12 Gene
May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation.