Aliases for ANKMY1 Gene

Aliases for ANKMY1 Gene

  • Ankyrin Repeat And MYND Domain Containing 1 2 3 5
  • ZMYND13 2 3 4
  • Ankyrin Repeat And MYND Domain-Containing Protein 1 3 4
  • Zinc Finger MYND Domain-Containing Protein 13 3 4
  • Testis-Specific Ankyrin-Like Protein 1 3 4
  • FLJ20499 2
  • ANKMY1 5
  • TSAL1 4

External Ids for ANKMY1 Gene

Previous GeneCards Identifiers for ANKMY1 Gene

  • GC02M241438
  • GC02M241739
  • GC02M241138
  • GC02M233174

Summaries for ANKMY1 Gene

GeneCards Summary for ANKMY1 Gene

ANKMY1 (Ankyrin Repeat And MYND Domain Containing 1) is a Protein Coding gene. Diseases associated with ANKMY1 include Venous Hemangioma and Sleeping Sickness.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ANKMY1 Gene

Genomics for ANKMY1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ANKMY1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ANKMY1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ANKMY1

Top Transcription factor binding sites by QIAGEN in the ANKMY1 gene promoter:
  • COUP
  • COUP-TF1
  • STAT3

Genomic Locations for ANKMY1 Gene

Latest Assembly
100,578 bases
Minus strand

Previous Assembly
(GRCh37/hg19 by Entrez Gene)
81,689 bases
Minus strand

(GRCh37/hg19 by Ensembl)
89,788 bases
Minus strand

Genomic View for ANKMY1 Gene

Genes around ANKMY1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKMY1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKMY1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKMY1 Gene

Proteins for ANKMY1 Gene

  • Protein details for ANKMY1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat and MYND domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • B2RB78
    • Q4ZFV3
    • Q8IYX5
    • Q8NDK5
    • Q9H0V8
    • Q9NX10

    Protein attributes for ANKMY1 Gene

    941 amino acids
    Molecular mass:
    105516 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ANKMY1 Gene


neXtProt entry for ANKMY1 Gene

Post-translational modifications for ANKMY1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ANKMY1 Gene

Domains & Families for ANKMY1 Gene

Gene Families for ANKMY1 Gene

Protein Domains for ANKMY1 Gene

  • Zn-finger, MYND type

Suggested Antigen Peptide Sequences for ANKMY1 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger MYND domain-containing protein 13 (ANKY1_HUMAN)
  • ANKMY1 protein (Q6GPI0_HUMAN)
genes like me logo Genes that share domains with ANKMY1: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ANKMY1 Gene

Function for ANKMY1 Gene

Phenotypes From GWAS Catalog for ANKMY1 Gene

Gene Ontology (GO) - Molecular Function for ANKMY1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ANKMY1: view
genes like me logo Genes that share phenotypes with ANKMY1: view

miRNA for ANKMY1 Gene

miRTarBase miRNAs that target ANKMY1

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ANKMY1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKMY1 Gene

Localization for ANKMY1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ANKMY1 gene
Compartment Confidence
nucleus 3
cytosol 3
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nuclear bodies (2)
  • Nucleoplasm (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKMY1 Gene

Pathways & Interactions for ANKMY1 Gene

PathCards logo

SuperPathways for ANKMY1 Gene

No Data Available

Interacting Proteins for ANKMY1 Gene

STRING Interaction Network Preview (showing top 1 STRING interactants - click image to see details)
STRING Interaction Network
Selected Interacting proteins: ENSP00000385887 Q9P2S6-ANKY1_HUMAN for ANKMY1 Gene via STRING IID

Gene Ontology (GO) - Biological Process for ANKMY1 Gene


No data available for Pathways by source and SIGNOR curated interactions for ANKMY1 Gene

Drugs & Compounds for ANKMY1 Gene

No Compound Related Data Available

Transcripts for ANKMY1 Gene

mRNA/cDNA for ANKMY1 Gene

20 NCBI additional mRNA sequence :
24 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ANKMY1

Alternative Splicing Database (ASD) splice patterns (SP) for ANKMY1 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19
SP1: - - - -
SP2: - - - - - - -
SP3: - - - - - - -
SP4: - - - -
SP5: - -

Relevant External Links for ANKMY1 Gene

GeneLoc Exon Structure for

Expression for ANKMY1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ANKMY1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

  • Testis (Reproductive System)

mRNA differential expression in normal tissues according to GTEx for ANKMY1 Gene

This gene is overexpressed in Testis (x6.2).

Protein differential expression in normal tissues from HIPED for ANKMY1 Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ANKMY1 Gene

Protein tissue co-expression partners for ANKMY1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ANKMY1

SOURCE GeneReport for Unigene cluster for ANKMY1 Gene:


Evidence on tissue expression from TISSUES for ANKMY1 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with ANKMY1: view

Primer products for research

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKMY1 Gene

Orthologs for ANKMY1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKMY1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ANKMY1 30 31
  • 97.88 (n)
(Canis familiaris)
Mammalia ANKMY1 30 31
  • 77.62 (n)
(Mus musculus)
Mammalia Ankmy1 30 17 31
  • 73.58 (n)
(Rattus norvegicus)
Mammalia Ankmy1 30
  • 71.96 (n)
(Bos Taurus)
Mammalia ANKMY1 31
  • 69 (a)
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 65 (a)
-- 31
  • 56 (a)
-- 31
  • 48 (a)
-- 31
  • 26 (a)
(Monodelphis domestica)
Mammalia ANKMY1 31
  • 44 (a)
(Gallus gallus)
Aves ANKMY1 30 31
  • 58.56 (n)
(Anolis carolinensis)
Reptilia ANKMY1 31
  • 41 (a)
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia ankmy1 30
  • 56.46 (n)
(Danio rerio)
Actinopterygii ankmy1 30 31
  • 49.5 (n)
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 37 (a)
Species where no ortholog for ANKMY1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for ANKMY1 Gene

Gene Tree for ANKMY1 (if available)
Gene Tree for ANKMY1 (if available)
Evolutionary constrained regions (ECRs) for ANKMY1: view image

Paralogs for ANKMY1 Gene

(3) SIMAP similar genes for ANKMY1 Gene using alignment to 14 proteins:

  • C9J176_HUMAN
  • C9J5V7_HUMAN
  • C9JZ56_HUMAN
  • F5H558_HUMAN
  • H7C254_HUMAN
  • J3KQ07_HUMAN
  • J3KQ21_HUMAN
genes like me logo Genes that share paralogs with ANKMY1: view

No data available for Paralogs for ANKMY1 Gene

Variants for ANKMY1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ANKMY1 Gene

SNP ID Clinical significance and condition Chr 02 pos Variation AA Info Type
rs140796181 Benign: not provided 240,500,539(-) G/A
NM_001282771.3(ANKMY1):c.2553C>T (p.Ala851=)
rs145705338 Benign: not provided 240,524,238(-) G/A
NM_001282771.3(ANKMY1):c.1479C>T (p.Arg493=)
rs150525285 Benign: not provided 240,529,333(-) G/T
NM_001282771.3(ANKMY1):c.657C>A (p.Ala219=)
rs72998048 Likely Benign: not provided 240,529,188(-) G/T
NM_001282771.3(ANKMY1):c.802C>A (p.His268Asn)
rs74001686 Benign: not provided 240,529,355(-) C/G
NM_001282771.3(ANKMY1):c.635G>C (p.Ser212Thr)

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for ANKMY1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for ANKMY1 Gene

Variant ID Type Subtype PubMed ID
esv1184193 CNV insertion 17803354
esv2721934 CNV deletion 23290073
esv2759119 CNV gain 17122850
esv3561297 CNV deletion 23714750
esv3575343 CNV gain 25503493
esv3594801 CNV gain 21293372
esv3594802 CNV gain 21293372
esv3594803 CNV loss 21293372
esv5720 OTHER inversion 19470904
nsv1001262 CNV gain 25217958
nsv10226 CNV gain 18304495
nsv1160908 CNV duplication 26073780
nsv3239 CNV insertion 18451855
nsv438384 CNV loss 16468122
nsv508899 CNV insertion 20534489
nsv515975 CNV gain 19592680
nsv819352 CNV loss 19587683
nsv821937 CNV gain 20364138
nsv834586 CNV loss 17160897
nsv955289 CNV deletion 24416366
nsv955290 CNV deletion 24416366
nsv956688 CNV deletion 24416366
nsv997288 CNV gain 25217958
nsv999050 CNV gain 25217958

Variation tolerance for ANKMY1 Gene

Residual Variation Intolerance Score: 93.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.55; 72.11% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ANKMY1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKMY1 Gene

Disorders for ANKMY1 Gene

MalaCards: The human disease database

(3) MalaCards diseases for ANKMY1 Gene - From: COP

Disorder Aliases PubMed IDs
venous hemangioma
sleeping sickness
  • african sleeping sickness
rapp-hodgkin syndrome
  • rhs
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for ANKMY1

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with ANKMY1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ANKMY1 Gene

Publications for ANKMY1 Gene

  1. New gene functions in megakaryopoiesis and platelet formation. (PMID: 22139419) Gieger C … Soranzo N (Nature 2011) 3 41
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  5. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. (PMID: 28611215) Fei T … Brown M (Proceedings of the National Academy of Sciences of the United States of America 2017) 3

Products for ANKMY1 Gene

Sources for ANKMY1 Gene