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Aliases for ANKMY1 Gene

Aliases for ANKMY1 Gene

  • Ankyrin Repeat And MYND Domain Containing 1 2 3 5
  • Zinc Finger MYND Domain-Containing Protein 13 3 4
  • Testis-Specific Ankyrin-Like Protein 1 3 4
  • ZMYND13 3 4
  • Ankyrin Repeat And MYND Domain-Containing Protein 1 3
  • TSAL1 4

External Ids for ANKMY1 Gene

Previous GeneCards Identifiers for ANKMY1 Gene

  • GC02M241438
  • GC02M241739
  • GC02M241138
  • GC02M233174

Summaries for ANKMY1 Gene

GeneCards Summary for ANKMY1 Gene

ANKMY1 (Ankyrin Repeat And MYND Domain Containing 1) is a Protein Coding gene.

Additional gene information for ANKMY1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKMY1 Gene

Genomics for ANKMY1 Gene

GeneHancer (GH) Regulatory Elements for ANKMY1 Gene

Promoters and enhancers for ANKMY1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I240556 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE 557.6 +11.5 11541 1.7 CTCF PKNOX1 MAX ARID4B BACH1 SIN3A BMI1 IRF4 RAD21 POLR2A ANKMY1 PIR41651 DUSP28 PIR62560
GH02I241543 Enhancer 1.2 Ensembl ENCODE 36.4 -977.0 -976992 4.4 HDGF PKNOX1 ZNF133 ARID4B YBX1 ZNF2 ZNF48 ETS1 ZNF121 ZNF766 ENSG00000223374 MTERF4 ATG4B ANKMY1 ING5 CAPN10 FARP2 SNED1 D2HGDH DTYMK
GH02I240558 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 17.6 +7.9 7888 4.8 HDGF CLOCK FOXA2 SMAD1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 DUSP28 ANKMY1 RNPEPL1
GH02I241313 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 16.4 -746.8 -746844 4.9 CLOCK ZFP64 FEZF1 DMAP1 IRF4 YY1 E2F8 ZNF143 SP3 NFYC SEPT2 HDLBP FARP2 ANKMY1 ANO7 ENSG00000223374 LINC01238 D2HGDH LINC01237 ING5
GH02I241148 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 15.8 -581.2 -581190 3.3 HDGF PKNOX1 FOXA2 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF213 E2F8 PASK PPP1R7 ANKMY1 ENSG00000223374 GC02P241182
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ANKMY1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ANKMY1 gene promoter:

Genomic Locations for ANKMY1 Gene

Genomic Locations for ANKMY1 Gene
chr2:240,479,422-240,569,209
(GRCh38/hg38)
Size:
89,788 bases
Orientation:
Minus strand
chr2:241,418,839-241,508,626
(GRCh37/hg19)

Genomic View for ANKMY1 Gene

Genes around ANKMY1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKMY1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKMY1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKMY1 Gene

Proteins for ANKMY1 Gene

  • Protein details for ANKMY1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9P2S6-ANKY1_HUMAN
    Recommended name:
    Ankyrin repeat and MYND domain-containing protein 1
    Protein Accession:
    Q9P2S6
    Secondary Accessions:
    • B2RB78
    • Q4ZFV3
    • Q8IYX5
    • Q8NDK5
    • Q9H0V8
    • Q9NX10

    Protein attributes for ANKMY1 Gene

    Size:
    941 amino acids
    Molecular mass:
    105516 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ANKMY1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ANKMY1 Gene

Post-translational modifications for ANKMY1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ANKMY1 Gene

Domains & Families for ANKMY1 Gene

Gene Families for ANKMY1 Gene

Suggested Antigen Peptide Sequences for ANKMY1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ANKMY1: view

No data available for UniProtKB/Swiss-Prot for ANKMY1 Gene

Function for ANKMY1 Gene

Phenotypes From GWAS Catalog for ANKMY1 Gene

Gene Ontology (GO) - Molecular Function for ANKMY1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ANKMY1: view
genes like me logo Genes that share phenotypes with ANKMY1: view

Animal Model Products

miRNA for ANKMY1 Gene

miRTarBase miRNAs that target ANKMY1

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKMY1 Gene

Localization for ANKMY1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ANKMY1 gene
Compartment Confidence
nucleus 3
cytosol 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nuclear bodies (2)
  • Nucleus (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKMY1 Gene

Pathways & Interactions for ANKMY1 Gene

SuperPathways for ANKMY1 Gene

No Data Available

Interacting Proteins for ANKMY1 Gene

Gene Ontology (GO) - Biological Process for ANKMY1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ANKMY1 Gene

Drugs & Compounds for ANKMY1 Gene

No Compound Related Data Available

Transcripts for ANKMY1 Gene

mRNA/cDNA for ANKMY1 Gene

(42) REFSEQ mRNAs :
(15) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(24) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKMY1 Gene

Ankyrin repeat and MYND domain containing 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKMY1 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19
SP1: - - - -
SP2: - - - - - - -
SP3: - - - - - - -
SP4: - - - -
SP5: - -
SP6:

Relevant External Links for ANKMY1 Gene

GeneLoc Exon Structure for
ANKMY1
ECgene alternative splicing isoforms for
ANKMY1

Expression for ANKMY1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ANKMY1 Gene

mRNA differential expression in normal tissues according to GTEx for ANKMY1 Gene

This gene is overexpressed in Testis (x6.2).

Protein differential expression in normal tissues from HIPED for ANKMY1 Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ANKMY1 Gene



Protein tissue co-expression partners for ANKMY1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ANKMY1 Gene:

ANKMY1

SOURCE GeneReport for Unigene cluster for ANKMY1 Gene:

Hs.656615

Evidence on tissue expression from TISSUES for ANKMY1 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with ANKMY1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKMY1 Gene

Orthologs for ANKMY1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKMY1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKMY1 33 34
  • 97.88 (n)
dog
(Canis familiaris)
Mammalia ANKMY1 33 34
  • 77.62 (n)
mouse
(Mus musculus)
Mammalia Ankmy1 33 16 34
  • 73.58 (n)
rat
(Rattus norvegicus)
Mammalia Ankmy1 33
  • 71.96 (n)
cow
(Bos Taurus)
Mammalia ANKMY1 34
  • 69 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 65 (a)
OneToMany
-- 34
  • 56 (a)
OneToMany
-- 34
  • 48 (a)
OneToMany
-- 34
  • 26 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia ANKMY1 34
  • 44 (a)
OneToOne
chicken
(Gallus gallus)
Aves ANKMY1 34 33
  • 58.56 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ANKMY1 34
  • 41 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ankmy1 33
  • 56.46 (n)
zebrafish
(Danio rerio)
Actinopterygii ankmy1 33 34
  • 49.5 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 37 (a)
OneToOne
Species where no ortholog for ANKMY1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKMY1 Gene

ENSEMBL:
Gene Tree for ANKMY1 (if available)
TreeFam:
Gene Tree for ANKMY1 (if available)

Paralogs for ANKMY1 Gene

genes like me logo Genes that share paralogs with ANKMY1: view

No data available for Paralogs for ANKMY1 Gene

Variants for ANKMY1 Gene

Sequence variations from dbSNP and Humsavar for ANKMY1 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000003999 -- 240,491,813(-) A/C genic_downstream_transcript_variant, intron_variant
rs1000007892 -- 240,470,942(-) G/A/T genic_downstream_transcript_variant, intron_variant
rs1000030916 -- 240,550,692(-) G/A intron_variant
rs1000046757 -- 240,529,412(-) T/C 5_prime_UTR_variant, coding_sequence_variant, intron_variant, missense_variant, non_coding_transcript_variant
rs1000074620 -- 240,487,696(-) T/C genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ANKMY1 Gene

Variant ID Type Subtype PubMed ID
esv1184193 CNV insertion 17803354
esv2721934 CNV deletion 23290073
esv2759119 CNV gain 17122850
esv3561297 CNV deletion 23714750
esv3575343 CNV gain 25503493
esv3594801 CNV gain 21293372
esv3594802 CNV gain 21293372
esv3594803 CNV loss 21293372
esv5720 OTHER inversion 19470904
nsv1001262 CNV gain 25217958
nsv10226 CNV gain 18304495
nsv1160908 CNV duplication 26073780
nsv3239 CNV insertion 18451855
nsv438384 CNV loss 16468122
nsv508899 CNV insertion 20534489
nsv515975 CNV gain 19592680
nsv819352 CNV loss 19587683
nsv821937 CNV gain 20364138
nsv834586 CNV loss 17160897
nsv955289 CNV deletion 24416366
nsv955290 CNV deletion 24416366
nsv956688 CNV deletion 24416366
nsv997288 CNV gain 25217958
nsv999050 CNV gain 25217958

Variation tolerance for ANKMY1 Gene

Residual Variation Intolerance Score: 93.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.55; 72.11% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ANKMY1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ANKMY1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKMY1 Gene

Disorders for ANKMY1 Gene

Additional Disease Information for ANKMY1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for ANKMY1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKMY1 Gene

Publications for ANKMY1 Gene

  1. New gene functions in megakaryopoiesis and platelet formation. (PMID: 22139419) Gieger C … Soranzo N (Nature 2011) 3 44 58
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  5. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. (PMID: 26871637) Yang X … Vidal M (Cell 2016) 3 58

Products for ANKMY1 Gene

Sources for ANKMY1 Gene

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