Aliases for ANKK1 Gene
External Ids for ANKK1 Gene
Previous GeneCards Identifiers for ANKK1 Gene
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009]
GeneCards Summary for ANKK1 Gene
ANKK1 (Ankyrin Repeat And Kinase Domain Containing 1) is a Protein Coding gene. Diseases associated with ANKK1 include Impulse Control Disorder and Alexithymia. Among its related pathways are Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is RIPK4.