Aliases for ANGPTL1 Gene
External Ids for ANGPTL1 Gene
Previous HGNC Symbols for ANGPTL1 Gene
Previous GeneCards Identifiers for ANGPTL1 Gene
Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues. This protein was found to be a secretory protein that does not act as an endothelial cell mitogen in vitro. [provided by RefSeq, Jul 2008]
GeneCards Summary for ANGPTL1 Gene
ANGPTL1 (Angiopoietin Like 1) is a Protein Coding gene. Diseases associated with ANGPTL1 include Hyperlipoproteinemia, Type I. Among its related pathways are Immune response IL-23 signaling pathway and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include signaling receptor binding. An important paralog of this gene is ANGPTL2.